Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0013362 (dysarthria)
 3,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
THG1L 12.0
C19orf2 11.5
PR domain containing 8 11.5
SANDO 11.3
KIAA0226 11.0
diacylglycerol kinase kappa 10.7
STM7 10.5
Troyer syndrome 10.5
PAPOLG 10.5
Hallervorden-Spatz syndrome 10.3
puratrophin-1 10.3
anoctamin 10 10.2
ANKFY1 10.2
SCA5 10.1
PANK2 10.1
PRDM8 10.0
SPG20 9.9
KIAA1840 9.9
junctional adhesion molecule 2 9.9
ZNF407 9.9
C19orf12 9.8
ARSACS 9.8
FAM36A 9.7
AARS2 9.7
glutaryl CoA dehydrogenase 9.7
LRP12 9.7
phosphodiesterase 8B 9.7
spartin 9.7
PKAN 9.6
CSRP1 9.6
G protein-regulated inducer of neurite outgrowth 1 9.6
UBQLN4 9.6
CMTX5 9.6
ZFYVE26 9.5
SCA11 9.5
RCAN2 9.5
KIAA1202 9.5
SPG15 9.4
KCNC3 9.4
SLC25A32 9.3
TSFM 9.3
EIF2AK1 9.3
SCA8 9.3
SAX2 9.2
ADCK3 9.1
Prolyl endopeptidase-like 9.1
CACH 9.0
SCA10 9.0
UBTF 9.0
TRNT1 9.0
SURF-1 9.0
ANO10 9.0
spinocerebellar ataxia type 2 8.9
SLC44A1 8.9
pantothenate kinase 8.9
VPS13A 8.8
FRDA 8.8
PREPL 8.8
AFG3L2 8.8
RNASEH1 8.8
EA2 8.8
GTPase regulator associated with focal adhesion kinase 8.8
GRAF 8.7
polyadenylate binding protein 8.7
SPG3 8.7
SCA2 8.7
SACS 8.7
SCA12 8.7
APTX 8.6
fatty acid 2-hydroxylase 8.6
FARS2 8.6
CACNB4 8.6
SSF1 8.5
ribonuclease H1 8.5
Phosphomannomutase 8.5
POLG 8.5
Caytaxin 8.5
CPA4 8.5
SCA1 8.4
SCA17 8.4
SCA3 8.4
SCA7 8.4
EIF2B2 8.3
MYOT 8.3
KIF1C 8.3
DNA polymerase gamma 8.3
choline transporter-like protein 1 8.3
SPG11 8.3
EIF2S1 8.2
EIF2B 8.2
calmodulin-like skin protein 8.2
SPG2 8.2
LMN 8.2
EPM2A 8.2
FHM2 8.2
SPTBN2 8.2
KMT2B 8.2
frataxin 8.1
Mixed lineage kinase 8.1
CNN1 8.1
TWINKLE 8.1
InsP3R1 8.0
JAM2 8.0
Spinocerebellar ataxia type 7 8.0
CACNA1A 8.0
Kell blood group 8.0
Aristaless-related homeobox 8.0
SLC19A3 8.0
PPM1B 8.0
MTO1 7.9
SPG10 7.9
NOP56 7.9
FGF14 7.9
ATP1A3 7.9
McLeod syndrome 7.9
ARHGAP26 7.8
JAM3 7.8
oligophrenin-1 7.8
C10orf2 7.7
Synphilin-1 7.7
PTGIS 7.7
pristanoyl-CoA oxidase 7.7
MT-ND5 7.7
RFXANK 7.7
GIPC1 7.6
IL13RA2 7.5
fatty acid hydroxylase 7.5
FZR1 7.5
dentatorubral-pallidoluysian atrophy 7.5
ACTG2 7.5
NPC2 7.5
SYNE1 7.5
BCKDHB 7.5
Hexosaminidase 7.5
SCA6 7.4
TBC1D24 7.4
DRPLA 7.4
PolB 7.4
SIL1 7.4
PRPS1 7.4
thymidine kinase 2 7.4
EIF2AK2 7.3
HLA-B51 7.3
MRPP2 7.3
PPP2R2B 7.3
LRFI 7.3
CRMP5 7.3
Na+,K+ ATPase 7.3
SPG7 7.3
alsin 7.3
Down syndrome candidate region 1 7.3
NSA 7.3
HDJ-2 7.2
ARRB2 7.2
PLA2G6 7.2
CADASIL 7.2
SLC20A2 7.2
AIFM1 7.2
SLC1A3 7.2
ataxin-1 7.2
more...
Disease
Fitzsimmons syndrome 13.0
Dysarthria-clumsy hand syndrome 13.0
Spina bifida with hydrocephalus 13.0
Motor speech disorder 13.0
palatoplegia 12.5
Ataxic dysarthria 12.3
childhood cerebellar astrocytoma 12.0
Facial lymphedema 12.0
Familial visceral neuropathy 12.0
SCA25 11.7
SAX1 11.7
Dysprosody 11.7
Dysfluency 11.7
SCA20 11.7
Hypokinetic dysarthria 11.6
SCA23 11.6
Neuro-Behcet disease 11.5
SPOAN 11.5
Peripheral sensorimotor neuropathy 11.5
SCA4 11.5
SANDO 11.3
Apraxia of speech 11.2
Progressing stroke 11.0
SCA18 11.0
Progressive cerebellar ataxia 11.0
SCA26 11.0
Bulbar weakness 11.0
CAMOS 11.0
Worster-Drought syndrome 11.0
Paraneoplastic cerebellar degeneration 10.9
Hypoglossal nerve palsy 10.9
Olivary hypertrophy 10.7
glossoplegia 10.7
SCA13 10.7
Central alveolar hypoventilation syndrome 10.7
torsion spasm 10.7
SCA5 10.7
Migraine variants 10.7
Behr syndrome 10.6
anarthria 10.5
moria 10.5
adult GM1 gangliosidosis 10.5
Verbal dyspraxia 10.5
Macular dystrophy 10.5
SCA28 10.4
Speech impairment 10.3
stage IIIA breast cancer 10.2
Paraneoplastic retinopathy 10.2
Basilar migraine 10.2
Lattice corneal dystrophy 10.2
MS-like syndrome 10.2
Brainstem encephalitis 10.2
SPG20 10.2
pseudobulbar palsy 10.1
speech disorder 10.1
Vertical gaze palsy 10.0
Cheiro-oral syndrome 10.0
Microcystic meningioma 10.0
Migrainous infarction 10.0
Aneurysm of the vein of Galen 10.0
aphemia 10.0
SCA16 10.0
SCA14 10.0
DFN2 9.9
SCA11 9.9
Hallervorden-Spatz disease 9.8
Partington syndrome 9.8
Gaze-evoked nystagmus 9.8
Episodic ataxia 9.8
dysbasia 9.8
swelling of the pituitary gland 9.7
SCA19 9.7
CMTX5 9.7
Secretory meningioma 9.7
organic delusional syndrome 9.6
alalia 9.6
Striatonigral degeneration 9.6
SCA27 9.6
XXYY syndrome 9.5
FRDA 9.5
hereditary ataxia 9.5
SCA8 9.5
SPG15 9.5
Hoffmann's syndrome 9.5
Mitochondrial neurogastrointestinal encephalopathy 9.5
abulia 9.4
Subclavian artery aneurysm 9.3
focal chorioretinitis 9.3
Central pontine myelinolysis 9.3
organic personality syndrome 9.3
cerebellar syndrome 9.3
mutism 9.3
progressive bulbar palsy 9.2
Cardiac embolism 9.2
SACS 9.2
Progressive dementia 9.2
articulation disorder 9.2
Diffuse astrocytoma 9.1
SCA15 9.1
Marchiafava-Bignami disease 9.1
Pulmonary arteriovenous fistula 9.1
Lacunar infarction 9.1
Trigeminal neuropathy 9.0
Tonsillar herniation 9.0
Idiopathic thrombocytopenia 9.0
Roussy-Levy 9.0
Foville syndrome 9.0
primary lateral sclerosis 9.0
dysphasia 9.0
agrammatism 9.0
peripheral retinal degeneration 9.0
Persistent vegetative state 9.0
Dialysis dementia 8.9
hemiparesis 8.9
Allan-Herndon-Dudley syndrome 8.9
Gillespie syndrome 8.8
Severe hypothyroidism 8.8
Cerebral aspergillosis 8.8
apraxia 8.8
Alpers 8.7
basal ganglia disease 8.7
hypernasality 8.7
delayed speech 8.7
SCA12 8.7
SCA2 8.7
Cranial nerves 8.7
Cranial nerves 8.7
hyponasality 8.6
Spinocerebellar ataxia 8.5
SCA6 8.5
Opsoclonus myoclonus 8.5
Cerebral hyperperfusion syndrome 8.5
Neuroaxonal dystrophy 8.5
recurrent cholecystitis 8.5
olivopontocerebellar atrophy 8.4
choreoathetosis 8.4
dysphagia 8.4
disorders of copper metabolism 8.4
unknown primary cancer 8.4
SCA1 8.4
motor aphasia 8.4
SCA7 8.4
SCA17 8.3
Akinetic mutism 8.3
Corticobasal degeneration 8.3
EPM2B 8.3
Pelizaeus-Merzbacher 8.3
Primary progressive multiple sclerosis 8.3
alcoholic encephalopathy 8.3
Dercum's disease 8.3
Wound botulism 8.3
SPG11 8.3
Fahr's disease 8.3
Friedreich's ataxia 8.2
alcoholic cerebellar degeneration 8.2
PNKD 8.2
SPG2 8.2
quadriparesis 8.2
Chronic progressive external ophthalmoplegia 8.2
Machado-Joseph disease 8.2
more...
Symptom
Scanning speech 13.0
Gait deviation 13.0
dysarthria 13.0
Limb ataxia 11.5
Frozen gait 11.5
Facial grimacing 11.5
left carotid bruit 11.0
Truncal ataxia 10.7
Paroxysmal dystonia 10.7
localized weakness 10.7
Sensory ataxia 10.5
poor balance and coordination 10.5
Premature loss of teeth 10.5
Retropulsion 10.3
Ophthalmoparesis 10.2
quadrant anopsia 10.2
External ophthalmoplegia 10.2
Vertigo/dizziness 10.2
Ataxic 10.2
Transient neurological symptoms 10.0
hemiparesthesia 10.0
facial droop 10.0
ataxic gait 9.8
Tandem gait 9.7
clumsiness 9.5
dyslalia 9.5
Pyramidal signs 9.5
hemihypesthesia 9.4
Kayser-Fleischer ring 9.4
intention tremor 9.3
amimia 9.1
arm weakness 9.1
cerebellar ataxia 9.1
disturbed speech 9.0
disturbance of sensation 8.9
Flaccid paralysis 8.9
ataxia 8.9
staggering gait 8.5
drooling 8.4
Aphasic 8.3
astasia 8.1
Neurologic symptoms 8.1
athetosis 8.0
Spastic paraparesis 8.0
ophthalmoplegia 8.0
Lasegue's sign 8.0
Palatal myoclonus 8.0
abnormal gait 7.9
consciousness disturbance 7.9
fasciculation 7.9
bradykinesia 7.9
dystonia 7.9
incoordination 7.8
chorea 7.7
hemiplegia 7.7
asterixis 7.7
hypalgesia 7.6
Spastic 7.6
Kernig's sign 7.4
myoclonus 7.3
spasticity 7.3
Visual disturbances 7.2
paresis 7.2
vertigo 7.2
dysesthesia 7.2
clonus 7.1
aphonia 7.1
Bell's phenomenon 7.1
paraparesis 7.0
blurred vision 7.0
tremor 7.0
weakness 6.8
neck stiffness 6.8
corpulence 6.8
numbness 6.8
voice change 6.8
personality change 6.7
Parkinsonian tremor 6.6
delayed language development 6.6
paresthesia 6.6
hypotonia 6.6
gumma 6.5
loss of taste 6.5
hoarseness 6.4
muscle cramps 6.4
giddiness 6.4
giddiness 6.4
Cervical dystonia 6.4
Psychiatric symptoms 6.3
monoplegia 6.3
Visual symptoms 6.2
glossodynia 6.2
meningism 6.2
forgetfulness 6.2
loss of balance 6.2
blepharospasm 6.2
hypertonia 6.2
dizziness 6.2
lightheadedness 6.0
Involuntary Movement 6.0
loss of equilibrium 5.9
visual hallucination 5.9
tonic-clonic seizure 5.8
neurological disability 5.8
motor symptom 5.8
torticollis 5.7
scaly skin 5.6
hyperesthesia 5.6
Flare 5.6
muscle rigidity 5.6
jaw pain 5.5
prostration 5.5
aphagia 5.4
sleepiness 5.4
Opposition 5.4
tonic seizure 5.3
lethargy 5.3
memory loss 5.3
abnormal breathing 5.3
asthenia 5.3
inanition 5.2
headache 5.2
pallor 5.2
metamorphopsia 5.1
neck pain 5.1
syncopal episodes 5.1
dry skin 5.1
periorbital edema 5.1
apathy 5.0
auditory hallucination 5.0
photophobia 5.0
Decreased activity 5.0
sinus pressure 5.0
non-productive cough 4.9
urinary frequency 4.9
tinnitus 4.9
excessive sweating 4.9
twitching 4.9
stridor 4.9
anosmia 4.8
tingling 4.7
snoring 4.7
thirsty 4.7
Physical findings 4.7
nausea 4.7
hypersomnia 4.6
catatonia 4.5
vomiting 4.5
muscle stiffness 4.4
spasm 4.4
seizures 4.3
livedo 4.3
hepatosplenomegaly 4.3
orthopnea 4.2
Halo 4.2
blackout 4.2
DNA marker 4.2
Respiratory symptoms 4.2
facial pain 4.2
otalgia 4.1
more...
Drug
Lomerizine hydrochloride 12.0
Hirtonin 12.0
Bromisoval 11.0
Akineton 9.0
Cogentin 9.0
Cogentin 8.9
Artane 8.5
Miglustat 8.4
Artane 8.0
Tetrax 7.8
Zotepine 7.7
DBS 6.8
Paliperidone 6.3
Sinemet 6.3
CVA 6.2
Sinemet 6.1
Xeloda 5.8
Diamox 5.7
GVG 5.7
Metrizamide 5.4
Bactrim 5.4
Irinotecan 5.4
Gastro 5.2
CTA 5.2
Iopamidol 5.1
Zmax 5.0
Sinemet 5.0
CPM 4.8
IPD 4.8
EDR 4.7
Acyclovir 4.6
Piracetam 4.6
Caspofungin 4.6
Riboflavin 4.4
Pregabalin 4.3
CSF 4.2
AmBisome 4.0
Piperacillin 4.0
Meropenem 3.8
Digitalis 3.8
Meropenem 3.7
Fluconazole 3.7
Phenytoin 3.7
Frontal 3.6
Campath 3.5
Campath 3.5
DM1 3.4
Tacrolimus 3.3
Amiloride 3.2
Methylprednisolone 3.2
Parkin 3.2
Parkin 3.2
Prednisone 3.1
MDS 2.9
Infliximab 2.9
Infliximab 2.9
TMS 2.9
Azithromycin 2.8
Spectrum 2.6
Prednisolone 2.5
Vitamin E 2.4
Award 2.3
TTC 2.2
CPT-11 2.2
Portal 2.0
Propofol 2.0
ENT 2.0
vitamin E 1.9
Herceptin 1.9
Imatinib 1.8
Spectrum 1.7
HCG 1.7
Ringer's solution 1.6
Rituximab 1.6
CTX 1.6
ADM 1.4
Taxol 1.4
Atropine 1.4
CTX 1.3
G-CSF 0.7
CTX 0.6
THF 0.1
lysine -0.2
NADH -0.4
Nephron -0.5
lactose -1.0
ampicillin -1.0
Nephron -1.1
ROS -1.2
caffeine -1.4
Leaf -1.4
Cardiovasc -1.8
Dial -1.9
Dermatol -2.6
Enzyme
3-hydroxy-2-methylbutyryl-CoA dehydrogenase 11.5
pantothenate kinase 8.8
m-AAA protease 7.5
C1 esterase 7.0
deoxyguanosine kinase 6.9
phosphomannomutase 6.2
TSR 5.5
Lod 5.4
ceruloplasmin 5.4
thymidine phosphorylase 5.4
arylsulfatase A 4.8
CPM 4.7
phenylalanyl-tRNA synthetase 4.6
PME 4.5
alpha-L-iduronidase 4.5
biotinidase 4.4
succinyl-CoA synthetase 4.4
hexosaminidase 4.2
glucosylceramide synthase 4.1
tissue plasminogen activator 4.0
CYP27A1 4.0
CCS 3.8
thyroid peroxidase 3.8
PDH 3.6
GCA 3.6
methylenetetrahydrofolate reductase 3.6
methylenetetrahydrofolate reductase 3.6
NADH dehydrogenase 3.6
Alternating 3.4
acyl-CoA dehydrogenase 3.4
aconitase 3.3
acyl-CoA oxidase 3.1
SCS 3.1
creatine kinase 3.0
complex I 2.9
arylsulfatase 2.8
hypoxanthine-guanine phosphoribosyltransferase 2.7
BMT 2.7
sialidase 2.6
acyl-CoA dehydrogenase 2.6
glucocerebrosidase 2.5
sulfatase 2.4
PAL 2.4
PTA 2.3
alpha-galactosidase 2.3
aldolase 2.3
succinic dehydrogenase 2.3
glycerol-3-phosphate dehydrogenase 2.3
urokinase-type plasminogen activator 2.2
glycerol-3-phosphate dehydrogenase 2.2
beta-galactosidase 2.2
pyruvate dehydrogenase 2.2
PAM 2.2
DNA polymerase 2.2
botulinum neurotoxin 2.2
diaphorase 2.1
phosphoglycerate kinase 2.0
cytochrome oxidase 1.9
thromboplastin 1.7
APC 1.6
succinate dehydrogenase 1.6
AST 1.5
HSD 1.3
pyruvate dehydrogenase 1.3
pyruvate dehydrogenase 1.3
enolase 1.2
carbonic anhydrase 1.2
cathepsin B 1.0
glutamate dehydrogenase 1.0
glutamate dehydrogenase 0.9
neuraminidase 0.8
transglutaminase 0.8
kinesin 0.7
adenosine deaminase 0.7
adenosine deaminase 0.7
phosphorylase 0.6
acetylcholinesterase 0.6
ACE 0.5
cholinesterase 0.4
ribonuclease 0.4
ribonuclease 0.4
phospholipase A2 0.2
aspartate aminotransferase 0.2
ATPase 0.0
calcineurin -0.0
alanine aminotransferase -0.1
transcriptase -0.2
lactate dehydrogenase -0.2
renin -0.5
acid phosphatase -0.6
superoxide dismutase -0.8
ERK -0.9
RNase -1.0
RNA polymerase -1.0
RNase -1.1
MEK -1.1
catalase -1.1
endonuclease -1.1
lipase -1.1
phosphodiesterase -1.2
glutathione peroxidase -1.4
alkaline phosphatase -1.5
proteasome -1.8
thrombin -2.0
protein kinase -2.3
mitogen-activated protein kinase -2.5
peroxidase -3.0
Compound
2-methyl-3-hydroxybutyryl-CoA 10.0
N-acetylleucine 9.9
N-acetylleucine 9.9
N-acetylleucine 9.6
N-acetylleucine 9.2
Trimeprazine 9.0
Pantothenate 8.0
Trihexyphenidyl 7.1
Valacyclovir 6.9
DBS 6.8
Pyridostigmine 6.6
TETA 6.6
Riluzole 6.4
Tetrabenazine 6.2
MCNU 6.0
Clonazepam 5.8
A 71 5.7
IMP 5.7
Capecitabine 5.6
GeO2 5.6
Filipin 5.4
A 42 5.3
PDQ 5.3
DCI 5.2
Trazodone 5.1
Levetiracetam 5.1
FAP 5.1
FAP 5.1
Botulinum toxin type A 5.0
MHS 4.9
Acetazolamide 4.9
GM2 4.9
IPD 4.9
Mexiletine 4.8
Topiramate 4.8
Succinylcholine 4.7
Edaravone 4.7
PSP 4.7
Meperidine 4.6
Acyclovir 4.6
Lip 4.6
SSD 4.4
EAA 4.4
TBC 4.4
coenzyme Q10 4.4
Riboflavin 4.4
o,p'-DDD 4.4
HMM 4.3
Cystine 4.3
Morin 4.3
HCP 4.3
MSG 4.2
His 4.2
Zolpidem 4.2
ANCA 4.2
Bismuth 4.2
Piperacillin 4.1
DPA 4.1
DPA 4.1
DPA 4.1
DPA 4.1
DPA 4.1
L-DOPA 4.1
Azathioprine 4.1
CAA 4.0
Creatine 4.0
Coenzyme Q10 3.8
Levofloxacin 3.8
Baclofen 3.8
Ursodeoxycholic acid 3.8
MCA 3.8
Thiamine 3.8
MCA 3.8
CCS 3.8
Heroin 3.7
Amitriptyline 3.7
N-acetylaspartate 3.7
Parks 3.7
Cystine 3.6
Metoclopramide 3.6
Methotrexate 3.6
DDVP 3.6
ANA 3.6
ANA 3.6
MTX 3.5
RELA 3.5
Voriconazole 3.5
COX 3.4
tetradecyl 3.4
tetradecyl 3.4
SAH 3.4
5-HTP 3.4
DPH 3.3
Biotin 3.3
Methylprednisolone 3.3
5-HTP 3.3
Norton 3.3
DTPA 3.3
DIC 3.3
Olanzapine 3.2
Nodular 3.2
Ceftriaxone 3.2
PDH 3.1
MEP 3.1
XPA 3.1
T 1 3.1
XPA 3.1
Valproic acid 3.0
Mendel 3.0
Bromocriptine 3.0
MEP 2.9
Sialic acid 2.9
Isoproterenol 2.9
DMD 2.9
Coronal 2.9
Lithium 2.9
Midazolam 2.8
GPT 2.8
GM1 2.8
FTA 2.8
CoQ 2.8
Homocysteine 2.7
Homocysteine 2.7
TBI 2.7
Ubiquitin 2.7
TTS 2.6
Thymidine 2.6
NIDA 2.6
TTP 2.6
delta-aminolevulinic acid 2.6
CBDCA 2.6
CBDCA 2.6
Neuronal 2.6
Uric acid 2.6
Maps 2.6
Guanine 2.5
LIN 2.5
Losartan 2.5
Prednisolone 2.5
Adenine 2.5
FMN 2.5
GD3 2.5
Thyroxine 2.5
AHA 2.5
A 3 2.5
PAS 2.4
betaine 2.4
5-hydroxytryptophan 2.4
Prednisone 2.4
PLP 2.4
TAP 2.4
Valproic acid 2.3
folinic acid 2.3
2-nonenal 2.3
Dopa 2.3
T11 2.2
6-12 2.2
Choline 2.2
BNP 2.2
copper 2.2
more...