Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0013362 (dysarthria)
 3,768 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Due to proliferation of the fatty tissue in the neck and depending on the degree of compression of the pharynx, larynx, vessels, nerve trunks the patients show, respiratory disorders, swallowing disturbances, dysarthria, stenocardia, neck and occipital pain, scalenus syndrome, cervicobrachialgia, posterior cervical sympathetic syndrome, disorders of the cerebral and spinal blood circulation. Involvement of both the central and peripheral nervous system are observed in Madelung's disease.
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PMID:[Nervous system involvement in Madelung's syndrome]. 144 91

Benign symmetric lipomatosis (Madelung disease) is a rare disorder of unknown etiology characterized by diffuse growth of unencapsulated lipomas predominantly in the head, neck and shoulder region. Involvement of the tongue has been previously described in only five cases. A 49-year-old man with alcoholic liver cirrhosis presented with an 11-year history of benign symmetric lipomatosis complaining of increasing dysphagia, dysarthria and hoarseness. Clinical intraoral examination revealed asymmetric, globular, firm, circumscribed masses on both borders of the tongue. During surgery, the masses seemed encapsulated from surrounding muscles and could easily be extirpated. However, "satellite fat cells" became obvious, which might give rise to the development of new lipomas.
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PMID:Encapsulated lipomas of the tongue in benign symmetric lipomatosis. 1919 64