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Pivot Concepts:
Gene/Protein
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Drug
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Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
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Query: UMLS:C0013362 (
dysarthria
)
3,768
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A positive relationship between rhythm perception and improved understanding of a naturally dysrhythmic speech signal, ataxic
dysarthria
, has been previously reported [Borrie, Lansford, and
Barrett
. (2017). J. Speech Lang. Hear. Res. 60, 3110-3117]. The current follow-on investigation suggests that this relationship depends on the nature of the dysrhythmia. When the corrupted rhythm cues are relatively predictable, affording some learnable acoustic regularity, the relationship is replicated. However, this relationship is nonexistent, along with any intelligibility improvements, when the corrupted rhythm cues are unpredictable. Findings highlight a key role for rhythm perception and distributional regularities in adaptation to dysrhythmic speech.
...
PMID:Understanding dysrhythmic speech: When rhythm does not matter and learning does not happen. 2985 10
Purpose Despite the import of conversational entrainment to successful spoken dialogue, the systematic characterization of this behavioral syncing phenomenon represents a critical gap in the field of speech pathology. The goal of this study was to acoustically characterize conversational entrainment in the context of
dysarthria
using a multidimensional approach previously validated in healthy populations (healthy conversations; Borrie,
Barrett
, Willi, & Berisha, 2019). Method A large corpus of goal-oriented conversations between participants with
dysarthria
and healthy participants (disordered conversations) was elicited using a "spot the difference" task. Expert clinical assessment of entrainment and a measure of conversational success (communicative efficiency) was obtained for each of the audio-recorded conversations. Conversational entrainment of acoustic features representing rhythmic, articulatory, and phonatory dimensions of speech was identified using cross-recurrence quantification analysis with clinically informed model parameters and validated with a sham condition involving conversational participants who did not converse with one another. The relationship between conversational entrainment and communicative efficiency was examined. Results Acoustic evidence of entrainment was observed in phonatory, but not rhythmic and articulatory, behavior, a finding that differs from healthy conversations in which entrainment was observed in all speech signal dimensions. This result, that disordered conversations showed less acoustic entrainment than healthy conversations, is corroborated by clinical assessment of entrainment in which the disordered conversations were rated, overall, as being less in sync than healthy conversations. Furthermore, acoustic entrainment was predictive of communicative efficiency, corroborated by a relationship between clinical assessment and the same outcome measure. Conclusions The findings confirm our hypothesis that the pathological speech production parameters of
dysarthria
disrupt the seemingly ubiquitous phenomenon of conversational entrainment, thus advancing entrainment deficits as an important variable in
dysarthria
, one that may have causative effects on the success of everyday communication. Results further reveal that while this approach provides a broad overview, methodologies for characterizing conversational entrainment in
dysarthria
must continue to be developed and refined, with a focus on clinical utility. Supplemental Material https://osf.io/ktg5q.
...
PMID:Sync Pending: Characterizing Conversational Entrainment in Dysarthria Using a Multidimensional, Clinically Informed Approach. 3185 8