Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0013080 (Down syndrome)
14,180 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein chromosome 21 1620 Sep 908 amyloid precursor protein 472 Mol 388 alpha-fetoprotein 298 chorionic gonadotropin 189 DYRK1A 164 GATA1 149 superoxide dismutase 126 She 120 APP 105 amyloid beta 99 pregnancy-associated plasma protein A 86 FISH 84 AFP 77 calcineurin 77 telomeric 70 lymphoid 68 insulin 61 erythroid 61 SOD1 61 GABA 61 RCAN1 60 apolipoprotein E 57 HLA 56 RUNX1 55 Rett syndrome 55 AML 55 collagen 55 X-linked 54 interferon 54 thymus 52 cytokine 52 MRI 52 SOD 52 ATP 52 glutathione peroxidase 51 IgA 49 precursor protein 49 DSCR1 48 CA1 48 axonal 46 S100B 44 p53 43 MNB 42 ALL 42 choline acetyltransferase 42 tau protein 42 p13 41 ETS2 41 catalase 39 megakaryocyte 39 acetylcholinesterase 39 olfactory 38 ubiquitin 38 polypeptide 38 neurofibromatosis 38 glycoprotein 37 hemoglobin 36 Alpha-fetoprotein 36 nerve growth factor 36 Mot 35 Pol 35 methylenetetrahydrofolate reductase 35 brain-derived neurotrophic factor 33 ERG 33 strabismus 32 FAB 31 p11 31 AML1 31 peroxidase 31 Y chromosome 31 glial fibrillary acidic protein 31 amyloid protein 30 BACE1 29 STR 29 HCG 29 surface antigen 29 MTRR 28 phosphatase 28 more...

Disease Down syndrome 14180 Alzheimer's disease 1850 trisomy 894 mental retardation 785 mental retardation 776 dementia 665 leukemia 656 cancer 545 Edwards 457 autism 398 heart disease 352 acute myeloid leukemia 306 abortion 285 trisomy 13 256 cognitive impairment 199 acute lymphoblastic leukemia 188 epilepsy 185 Turner syndrome 177 plaque 173 hypothyroidism 168 genetic disorder 168 fragile X syndrome 167 tumor 163 ventricular septal defect 161 developmental disabilities 154 diabetes 152 cerebral palsy 150 Parkinson's disease 146 TMD 130 Autism 128 Williams syndrome 123 septal defect 120 depression 118 pulmonary hypertension 115 obesity 110 hypertension 104 myelodysplastic syndrome 100 vascular disease 99 atrial septal defect 98 stroke 95 hypogonadotropic hypogonadism 95 acute leukemia 94 developmental delay 93 myeloproliferative disorders 88 triploidy 84 anemia 82 amyloidosis 79 dysplasia 77 Klinefelter's syndrome 76 hepatitis B 75 celiac disease 74 Huntington's disease 74 schizophrenia 72 moyamoya 72 Rett syndrome 72 cystic fibrosis 72 obstructive sleep apnea 71 megakaryocytic leukemia 70 Leukemia 69 preeclampsia 68 pneumonia 66 myeloid leukemia 66 leukemogenesis 62 premature aging 61 immunodeficiency 59 West 59 hernia 59 infertility 58 lymphoma 57 mental handicap 57 hydrocephalus 56 thrombocytopenia 53 amyotrophic lateral sclerosis 51 hygroma 51 cleft palate 48 periodontal disease 47 sleep apnea 47 thalassemia 45 HCG 44 heart failure 42 more...

Symptom seizures 157 hypotonia 113 pain 73 anesthesia 70 weakness 50 vomiting 48 hepatosplenomegaly 40 respiratory distress 35 overweight 35 regurgitation 34 diarrhea 31 ataxia 29 snoring 24 cough 23 memory loss 22 abdominal pain 22 constipation 22 dyspnea 18 fatigue 18 myoclonus 18 hepatomegaly 17 cyanosis 16 collapse 15 headache 15 thinning 14 stridor 12 HSA 11 splenomegaly 11 neck pain 11 discomfort 10 tremor 10 analgesia 10 torticollis 10 enuresis 9 lethargy 9 discomfort 9 distraction 9 dysarthria 8 sleepiness 8 pallor 8 agitation 8 hypothermia 7 dystonia 7 exhaustion 7 chorea 7 apathy 7 stigma 7 wheezing 7 tachypnea 7 drooling 6 hemiplegia 6 spasticity 6 anorexia 6 insomnia 5 erythema 5 chronic constipation 5 starvation 5 abnormal gait 5 ENT 5 catatonia 5 hypertonia 5 functional recovery 4 DNA marker 4 acute abdomen 4 physical appearance 4 tonic-clonic seizure 4 forgetfulness 3 Ill 3 nausea 3 back pain 3 hemoptysis 3 fasciculation 3 masculinization 3 Multimorbidity 3 clonus 3 fever of unknown origin 3 syncope 3 polyuria 3 bedwetting 2 asthenia 2 more...

Drug Dermatol 85 Cardiovasc 48 HCG 29 CSF 18 ETS 16 Spectrum 15 Spectrum 15 Leaf 14 lysine 14 vitamin E 14 TEL 13 IL-2 13 ascorbate 12 Posture 11 MDS 11 IFN-gamma 10 ROS 10 Frontal 10 caffeine 10 FAD 9 Monit 8 Epigallocatechin 8 Mutagen 8 ROC 7 ENT 7 THF 7 ABC 7 Palivizumab 6 MAP 6 anti-RSV 6 Vitamin E 5 Donepezil 5 Nephron 4 Portal 4 Growth hormone 4 MRC 4 Gel 3 Asn 3 Fraction 3 AraC 3 Growth hormone 3 Histamine 3 NADH 3 Prednisone 2 Nephron 2 Urokinase 2 nitroglycerin 2 Glutathione 2 PTH 2 Piracetam 2 IL-1ra 2 Asthma 2 Activin 2 ACT 2 GEO 2 Award 2 NBT 2 p75 2 Diurnal 2 Etoposide 2 Ethanol 2 Parkin 2 Vitamin B12 2 Vitamin B 2 niacin 2 ampicillin 2 Fluorescein 2 EE2 2 DM1 2 Albumin 2 uPA 2 Dakar 2 Parkin 2 Misoprostol 1 Glucantime 1 Depo-Provera 1 DDAVP 1 Kainic acid 1 Synthroid 1 Indomethacin 1 more...

Enzyme superoxide dismutase 173 calcineurin 83 protein kinase 74 acetylcholinesterase 54 ERK 53 glutathione peroxidase 52 peroxidase 47 catalase 44 choline acetyltransferase 42 focal adhesion kinase 41 methylenetetrahydrofolate reductase 35 methylenetetrahydrofolate reductase 35 mitogen-activated protein kinase 34 pregnancy-associated plasma protein-A 33 STR 29 alkaline phosphatase 26 cholinesterase 24 CD10 20 cystathionine beta-synthase 19 beta-secretase 18 methionine synthase reductase 17 CD13 17 ATPase 16 caspase-3 16 proteasome 15 phosphofructokinase 14 GSK 14 protein kinase C 14 methionine synthase 13 glutathione reductase 13 methionine synthase 13 enolase 12 complex I 11 reverse transcriptase 11 trypsin 11 DNA polymerase 9 glutathione S-transferase 9 ceruloplasmin 8 transglutaminase 8 phosphodiesterase 8 alanine aminotransferase 8 renin 8 adenylate cyclase 8 luciferase 8 tissue plasminogen activator 7 tyrosine hydroxylase 7 cdc2 7 gamma-glutamyl transpeptidase 6 carbonyl reductase 6 GAR 6 glucose-6-phosphate dehydrogenase 6 chymotrypsin 6 APC 6 thrombin 6 thyroid peroxidase 5 asparaginase 5 endonuclease 5 RNase 5 hypoxanthine-guanine phosphoribosyltransferase 5 RNase 5 pyruvate dehydrogenase 5 CaMKII 5 phosphatidylinositol 3-kinase 5 lactate dehydrogenase 5 ATP synthase 5 caspase-9 4 adenosine deaminase 4 sulfatase 4 insulin-degrading enzyme 4 RNA polymerase 4 cystathionine gamma-lyase 4 hexosaminidase 4 plasmin 4 pyruvate dehydrogenase 4 CLK1 4 protein phosphatase 2A 4 glyceraldehyde-3-phosphate dehydrogenase 4 carbonic anhydrase 4 adenosine deaminase 4 pyruvate dehydrogenase 4 more...

Compound Dec 946 DNA 813 Clin 755 oxygen 212 Retard 200 Cardiol 156 calcium 137 tyrosine 133 water 109 zinc 84 glucose 79 His 65 GABA 62 GABA 61 hydrogen 55 homocysteine 55 ATP 52 iron 52 glutamate 51 serine 50 silver 50 sodium 49 copper 48 threonine 38 potassium 37 TSH 35 creatinine 34 methionine 34 sulfate 33 phosphate 32 nitric oxide 30 Thyroid 30 cysteine 30 arginine 27 H2O2 27 Neuronal 24 selenium 24 acetate 23 DSM 23 proline 23 iodine 22 GTP 22 GSH 21 GSH 21 A 3 21 SDS 21 NMDA 20 leucine 20 barium 19 tryptophan 19 cAMP 19 lysine 19 tryptophan 18 5-HT 18 Congo red 17 tryptophan 17 tryptophan 17 noradrenaline 17 CBS 17 aluminum 16 H2S 16 glutamine 16 alanine 15 AMP 15 TNF 15 Phe 15 CO2 15 galactose 15 PGA 14 TOF 14 adenosylmethionine 13 ethanol 13 Cereb 13 TEL 13 A 1 13 vitamin D 13 retinoic acid 13 CMK 12 superoxide radical 12 PAS 11 more...

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