Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0013080 (Down syndrome)
14,180 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein chromosome 21 1620 Sep 908 amyloid precursor protein 472 Mol 388 alpha-fetoprotein 298 chorionic gonadotropin 189 DYRK1A 164 GATA1 149 superoxide dismutase 126 She 120 APP 105 amyloid beta 99 pregnancy-associated plasma protein A 86 FISH 84 AFP 77 calcineurin 77 telomeric 70 lymphoid 68 SOD1 61 GABA 61 erythroid 61 insulin 61 RCAN1 60 apolipoprotein E 57 HLA 56 RUNX1 55 AML 55 collagen 55 Rett syndrome 55 X-linked 54 interferon 54 SOD 52 MRI 52 cytokine 52 ATP 52 thymus 52 glutathione peroxidase 51 IgA 49 precursor protein 49 CA1 48 more...

Disease Down syndrome 14180 Alzheimer's disease 1850 trisomy 894 mental retardation 785 mental retardation 776 dementia 665 leukemia 656 cancer 545 Edwards 457 autism 398 heart disease 352 acute myeloid leukemia 306 abortion 285 trisomy 13 256 cognitive impairment 199 acute lymphoblastic leukemia 188 epilepsy 185 Turner syndrome 177 plaque 173 genetic disorder 168 hypothyroidism 168 fragile X syndrome 167 tumor 163 ventricular septal defect 161 developmental disabilities 154 diabetes 152 cerebral palsy 150 Parkinson's disease 146 TMD 130 Autism 128 Williams syndrome 123 septal defect 120 depression 118 pulmonary hypertension 115 obesity 110 hypertension 104 myelodysplastic syndrome 100 vascular disease 99 atrial septal defect 98 hypogonadotropic hypogonadism 95 more...

Symptom seizures 157 hypotonia 113 pain 73 anesthesia 70 weakness 50 vomiting 48 hepatosplenomegaly 40 overweight 35 respiratory distress 35 regurgitation 34 diarrhea 31 ataxia 29 snoring 24 cough 23 abdominal pain 22 constipation 22 memory loss 22 myoclonus 18 fatigue 18 dyspnea 18 hepatomegaly 17 cyanosis 16 headache 15 collapse 15 thinning 14 stridor 12 neck pain 11 splenomegaly 11 HSA 11 torticollis 10 tremor 10 analgesia 10 discomfort 10 distraction 9 discomfort 9 enuresis 9 lethargy 9 agitation 8 sleepiness 8 dysarthria 8 more...

Drug Dermatol 85 Cardiovasc 48 HCG 29 CSF 18 ETS 16 Spectrum 15 Spectrum 15 Leaf 14 vitamin E 14 lysine 14 IL-2 13 TEL 13 ascorbate 12 Posture 11 MDS 11 Frontal 10 caffeine 10 IFN-gamma 10 ROS 10 FAD 9 Mutagen 8 Monit 8 Epigallocatechin 8 ROC 7 ABC 7 THF 7 ENT 7 Palivizumab 6 MAP 6 anti-RSV 6 Vitamin E 5 Donepezil 5 MRC 4 Growth hormone 4 Portal 4 Nephron 4 Gel 3 Growth hormone 3 AraC 3 Histamine 3 more...

Enzyme superoxide dismutase 173 calcineurin 83 protein kinase 74 acetylcholinesterase 54 ERK 53 glutathione peroxidase 52 peroxidase 47 catalase 44 choline acetyltransferase 42 focal adhesion kinase 41 methylenetetrahydrofolate reductase 35 methylenetetrahydrofolate reductase 35 mitogen-activated protein kinase 34 pregnancy-associated plasma protein-A 33 STR 29 alkaline phosphatase 26 cholinesterase 24 CD10 20 cystathionine beta-synthase 19 beta-secretase 18 CD13 17 methionine synthase reductase 17 ATPase 16 caspase-3 16 proteasome 15 GSK 14 protein kinase C 14 phosphofructokinase 14 methionine synthase 13 glutathione reductase 13 methionine synthase 13 enolase 12 trypsin 11 complex I 11 reverse transcriptase 11 glutathione S-transferase 9 DNA polymerase 9 transglutaminase 8 renin 8 adenylate cyclase 8 more...

Compound Dec 946 DNA 813 Clin 755 oxygen 212 Retard 200 Cardiol 156 calcium 137 tyrosine 133 water 109 zinc 84 glucose 79 His 65 GABA 62 GABA 61 hydrogen 55 homocysteine 55 ATP 52 iron 52 glutamate 51 serine 50 silver 50 sodium 49 copper 48 threonine 38 potassium 37 TSH 35 methionine 34 creatinine 34 sulfate 33 phosphate 32 nitric oxide 30 Thyroid 30 cysteine 30 arginine 27 H2O2 27 Neuronal 24 selenium 24 DSM 23 acetate 23 proline 23 more...

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