Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0012872 (DNA marker)
 929 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A noncoding nuclear DNA marker sequence (Cpn1-1) was used to investigate subdivision in the grasshopper Chorthippus parallelus and deduce postglacial expansion patterns across its species range in Europe. Investigation of the spatial distribution of 71 Cpn1-1 haplotypes and estimation of levels of genetic differentiation (KST values) between populations and geographic regions provided evidence for subdivision of C. parallelus into at least five major geographic regions and indicated that the French form of C. parallelus originated after range expansion from a Balkan refugium. Further evidence for subdivision of C. parallelus between Italy and northern Europe suggests that the Alps may have formed a significant barrier to gene flow in this grasshopper.
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PMID:Postglacial expansion and genome subdivision in the European grasshopper Chorthippus parallelus. 771 54

A 300 bp portion of the mitochondrial cytochrome oxidase subunit I (COI) gene was used to investigate the intraspecific genetic structure of the European meadow grasshopper Chorthippus parallelus. Levels of genetic subdivision between geographical regions in Europe were assessed using the KST statistic and revealed patterns indicative of the postglacial history of this organism. Northern European populations are shown to share a very recent common ancestor with, and hence originate from, a Balkan expansion. Genetic distances between these areas and both southern Italy and central Spain are shown to be approximately equal, even though only the Spanish form is recognized as a distinct subspecies. Distance estimates indicate that the common ancestor of the two subspecies lived more than one glacial cycle ago, and the refugial populations have probably been diverging in isolation for five or six glacial cycles (approximately equal to 550,000 years). Comparisons are made to the analysis of a similar data set using an anonymous nuclear DNA marker (Cooper et al., 1995). Although the structure revealed is generally very similar, differences in the location of transition zones between different genetic forms of C. parallelus may reflect the different historical assortment of these molecules.
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PMID:mtDNA phylogeography and postglacial patterns of subdivision in the meadow grasshopper Chorthippus parallelus. 965 Feb 81