Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0012833 (dizziness)
 9,689 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In patients affected by high degree AV block without preexisting congestive heart failure there is no definite demonstration that DDD pacing gives real clinical advantages in respect to VVIR pacing. We performed an intrapatient, long-term study between the two pacing modes in 14 high degree AV block patients, using the Medtronic Synergyst 7027 dual chamber pacemaker, who could be programmed alternatively in DDD or VVIR mode. After a 4-week run-in period following the pacemaker implant, patients completed a randomized, double-blind, cross-over study to compare the effect of 6-week period VVIR and DDD pacing on symptoms and cardiovascular parameters. A semiquantitative score scale was used to quantify the symptoms of general well-being, palpitations, dizziness, pulsating sensation in the neck or abdomen, shortness of breath at rest and during effort, chest pain, and NYHA classification. The sum of symptom scores was 10.4 +/- 6.7 in VVIR period and 4.6 +/- 2.7 in DDD period (P less than 0.001); five patients (36%) crossed over early from VVIR to DDD because of intolerable symptoms; overall, eight patients preferred the DDD mode and no one preferred the VVIR. Cardiac output at rest (echo-Doppler method) was 4.7 +/- 1.4 versus 5.7 +/- 1.6 liter/min (P less than 0.01), body weight was 65.9 +/- 6.6 versus 64.9 +/- 6.1 kg (P less than 0.02), atrial natriuretic peptide was 236 +/- 112 versus 198 +/- 110 pg/mL (P less than 0.01), respectively, during VVIR and DDD modes. Effort tolerance was similar with the two modes of pacing (68 +/- 15 vs 70 +/- 18 watts/min).(ABSTRACT TRUNCATED AT 250 WORDS)
Pacing Clin Electrophysiol 1990 Dec
PMID:Intrapatient comparison between chronic VVIR and DDD pacing in patients affected by high degree AV block without heart failure. 170 47

In order to evaluate the diagnostic value of carotid sinus hypersensitivity (CSH) we have investigated 163 asymptomatic patients (88 male, 75 female, mean age 57.9 +/- 22.7 years) and 210 symptomatic patients (108 males, 102 females, mean age 61.1 +/- 28.1 years) with syncopes or dizziness. Thirty two of the 163 asymptomatic patients (20%) and 87 of the 210 symptomatic patients (41%) showed CSH (asystole greater than or equal to 3 sec during carotid sinus pressure). Male patients had a higher number of CSH than female (28% vs 10% in the asymptomatic group, 48% vs 34% in the symptomatic group). Electrophysiological investigations were performed in all 210 symptomatic patients. Normal electrophysiological results had 94 of the 210 patients. Thirty seven of these 94 patients showed CSH (39%). Prolonged sinus node recovery time (SNRT) and/or prolonged sinoatrial conduction time (SACT) were evaluated in 38 patients. Seventeen of the 38 patients had CSH (45%). Disorders of atrioventricular (AV) conduction were evaluated in 43 patients. Seventeen of the 43 patients showed CSH (40%). Thirty-five patients had both AV conduction disorders and prolonged SNRT or SACT. Sixteen of these 35 patients showed CSH (46%). In conclusion, no significant difference was found between patients with and without pathological electrophysiological results. The CSH is without value for predicting sinus node dysfunction and AV conduction disorder.
Pacing Clin Electrophysiol 1990 Dec
PMID:Diagnostic value of carotid sinus hypersensitivity. 170 94

This report describes treatment over a period of 6 years of Mien refugees from highland Laos in the Indochinese Psychiatric Program of the Oregon Health Sciences University (Portland, OR). The medical and psychiatric problems of 84 patients were presented through somatic symptoms such as headache, dizziness, or musculoskeletal pain. Primary care medical problems were identified and treated, with the major focus on the two most common psychiatric diagnoses: major depression and posttraumatic stress disorder. Cultural beliefs about illness and medication interfered with adherence to prescribed treatment. A marked sensitivity to side effects of certain antidepressants also resulted in subtherapeutic doses. Patients rarely volunteered their traumatic histories, psychiatric problems, or dissatisfaction with medications. However, the effective use of medication for somatic complaints, along with the continuing recognition of Mien health beliefs in psychosocial treatments, allowed for the development of a trusting doctor-patient relationship and continued psychiatric care.
J Nerv Ment Dis 1991 Dec
PMID:Posttraumatic stress disorder, depression, and somatic symptoms in U.S. Mien patients. 174 30

Computer-aided measurements of saccade-reflex reaction times, velocities, and accuracies have become important tools in the detection of central nervous system pathology. Because of improved knowledge of the reflex pathways in man, saccade testing can assist in differentiating between brain stem, cerebellar, or cerebral disorders and point toward unilateral lesions. Saccade-reflex testing is also useful in determining disability and measuring over time the course of central nervous system disorders. Further work, correlating lesions observed by high-resolution imaging techniques with abnormalities in reflexes, continues to improve the understanding of saccade mechanisms in man. Specific cases are used to show the effects of anatomic lesions on changes in saccade reflexes. The results from 100 consecutive patients evaluated for dizziness are provided in order to illustrate the prevalence of saccade abnormalities and the relationship between abnormalities in vestibular and slow and fast eye-movement reflexes. Patients complaining of disequilibrium and visual disturbances frequently have abnormalities in the saccade system, abnormalities which are often overlooked in present clinical testing of the dizzy patient.
Laryngoscope 1991 Dec
PMID:Clinical application of saccade-reflex testing in man. 176 99

The mean of the Norplant usage period of 338 acceptors was 44.4 months. Most users had poor education and low incomes; the lower their socioeconomic status, the longer they used the Norplant implant. Return to fertility 3 months after removal was 38.46%; after 6 months, 71.43%; after 9 months, 74.46%; and after 12 months, 75%. The continuation rate at year one was 82.84%; year 2, 74.85%; year 3, 68.34%; year 4, 64.79%; while year 5 was 8.58%. The mean removal time was 21 minutes. There was a very significant difference between trained and untrained removers in the duration of removal. The average number of capsules removed was 5.64. There was no significant difference between trained and untrained removers in successful capsule removal. Reasons for removal were expired date and non-medical complaints such as changing to other contraceptives and the wish to become pregnant; medical complaints were dizziness, vertigo, spotting and amenorrhea. Removal was prompted by acne, metrorrhagia, two or more medical complaints, menorrhagia, physical pain, tenderness at insertion site and spotting. There were no pregnancies found among acceptors. However, 5.92% of the acceptors were pregnant at the time of insertion because of misdiagnosis. It can be concluded that Norplant is effective, safe and acceptable but removal needs trained persons.
Adv Contracept 1991 Dec
PMID:The Norplant removal training and service at Dr Kariadi Hospital, Semarang, Indonesia. 177 63

It has been suggested that autoimmunity and genetic factors may play a specific role in the development of idiopathic hypoparathyroidism. We reported a case of idiopathic hypoparathyroidism complicated with chronic thyroiditis. The patient, a woman 40 years old, visited our clinic because of tetany of both hands and dizziness. She was of short stature with a round face. She also had a goiter, hypocalcemia, hyperphosphatemia and decreased parathyroidal function, but renal function was normal. Her TSH level was slightly high with a positive microsome test (x 1600), and the levels of thyroid hormones tended to be low. Based on Ellsworth-Howard test findings, a diagnosis of idiopathic hypoparathyroidism was made, with the complication of chronic thyroiditis confirmed by the thyroidal biopsy. Administration of l alpha-OH-D3 normalized the level of serum calcium. No special treatment was given for the chronic thyroiditis in order to observe its natural course. Her TSH returned to normal, and the level of thyroid hormones was increased to normal ranges. Tests were positive for anti-adrenal antibody and anti-gastric antibody. The complication of chronic thyroiditis, an autoimmune disease, and a positive finding for every antibody suggested the possible involvement of autoimmunity in the mechanism of development of idiopathic hypoparathyroidism. The administration of 1 alpha-OH-D3 resulted in an increase in the serum calcium level and also normalization of levels of TSH and thyroid hormones. Thus, it is likely that the elevation of the calcium ion or immunoregulation by active vitamin D may have induced the increase in thyroid hormone secretion.
Nihon Naibunpi Gakkai Zasshi 1991 Dec 20
PMID:[A case of idiopathic hypoparathyroidism complicated with chronic thyroiditis]. 178 1

Asymptomatic schoolchildren in Guinea Bissau were given approximately 10 mg of quinine/kg body weight once daily during 5 days (n = 15) or 3 days (n = 16) for treatment of P. falciparum. Five children had parasitemia on the seventh day of follow up. Adverse reactions were reported by 12 children during treatment, mainly mild tinnitus, dizziness and vomiting. Single daily doses were less effective than the divided doses previously used by us for the same short time period and also associated with more frequent adverse events.
Trop Med Parasitol 1991 Dec
PMID:Clearance of plasmodium falciparum after reduced single daily doses of quinine in asymptomatic children in Guinea Bissau. 179 38

The large number of antidepressants available provides a wide range of choice. While clinical effectiveness is the most important consideration, toxicity in overdose must be considered in the risk-benefit assessment of each antidepressant. There are almost 300 deaths each year in Britain from tricyclic overdose, and very few deaths from newer antidepressants. Fluvoxamine appears to have low toxicity in overdose. Symptoms are often minimal: nausea, vomiting, dizziness and somnolence. There is one reported case of prolonged cerebral depression after ingestion of 5.5 g. Overdoses of up to 9 g have produced minimal symptoms and full recovery. No deaths from overdose with fluvoxamine alone have been reported in the literature, although one death certificate in Britain has mentioned fluvoxamine as the cause of death. Fluvoxamine appears to be a valuable alternative to the tricyclic antidepressants, and has a high margin of safety in overdose.
Int Clin Psychopharmacol 1991 Dec
PMID:Overdose and safety with fluvoxamine. 180 34

Admissions of 762 patients for epileptic seizures and 1553 for dizziness were studied for the connection with the level of monthly and yearly solar activity in the 11-year solar cycle and with four levels of daily geomagnetic activity levels (400 epileptic patients and 802 patients suffering with dizziness). The most significant differences of the studied groups were in the male/female ratio in different conditions of solar and geomagnetic activity. Changes in the group of epileptic patients were accompanied by similar, but adverse changes in the group suffering from dizziness. Different conditions of responses of females and males to environmental changes can explain the demonstrated results.
Med Hypotheses 1991 Dec
PMID:Admissions of patients with epileptic seizures (E) and dizziness (D) related to geomagnetic and solar activity levels: differences in female and male patients. 180 61

Neurocardiovascular control during postural change was investigated in two teenage females with complaints of dizziness almost immediately on standing up. Blood pressure and heart rate were monitored continuously with a Finapres device. On standing there was a brief but marked fall in blood pressure between 5-10 s after the onset of the manoeuvre. The maximum fall in systolic and diastolic blood pressure was 65 mmHg and 40 mmHg respectively in the first subject, and 58 mmHg and 29 mmHg respectively in the second subject. In both, postural tachycardia was present after 1-2 min of standing with heart rate increasing by up to 39 beats/min in the first subject and 60 beats/min in the second subject. On a follow-up examination 3 years later these changes had disappeared in the first subject while they persisted in the second subject, when she was studied two years later. We conclude that in these patients initial postural dizziness is related to an excessive fall in blood pressure upon standing.
Clin Auton Res 1991 Dec
PMID:Postural dizziness and transient hypotension in two healthy teenagers. 182 61


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