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Target Concepts:
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Query: UMLS:C0012833 (
dizziness
)
9,689
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Lormetazepam
(0.5, 1, 2, 4, 8 mg)--a new benzodiazepine--was tested versus Pentobarbital (100 mg) under double blind conditions on 240 preoperative inpatients for night-time sedative and side effects after acute oral intake. Results are based on p less than 0.05. Additionally p less than 0.125 in binomial-two-sample-tests was accepted.
Lormetazepam
shows dose dependent increase in hypnotic effects (e.g. reduction in sleep latency and number of awakenings, increase of total sleep duration), and side effects (e.g. dopiness,
dizziness
), but no relevant change in vital signs. About 0.5 mg of
Lormetazepam
are equivalent to 100 mg of Pentobarbital. 2 mg of
Lormetazepam
seem to be the optimum dose regarding the relation between hypnotic and side effects. In the view of anaesthesists
Lormetazepam
is preferable to Pentobarbital because of more favorable safety aspects.
...
PMID:[Lormetazepam in preoperative sleeplessness. Dose dependance of the effect and comparison with 100 mg pentobarbital (author's transl)]. 3 99
Lormetazepam
, a relatively new benzodiazepine was compared in a randomised, double blind trial with diazepam for its effectiveness as an oral premedicant drug. A scoring system was used to assess sedation, relief of anxiety, nausea,
dizziness
and cardiovascular effects in two groups of patients having orthopaedic operations. Some statistical indication that lormetazepam has a greater anxiolytic effect than diazepam was found, but in assessing total effect using a known scoring system, no difference was demonstrated between the two drugs.
...
PMID:Oral lormetazepam in premedication. A comparison with diazepam. 287 76
