Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0012833 (dizziness)
 9,689 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The sick sinus syndrome is caused by dysfunction of the sinus node and includes various forms of arrhythmia. In its chronic form the underlying disease may affect not only the sinus node but also the atrial, junctional and intraventricular conduction tissue. The most important clinical symptoms are, in decreasing order, dizziness, syncope, palpitations, cardiac failure, systemic embolism, and cerebrovascular insult. The main diseases causing dysfunction of the sinus node are coronary heart disease, myocarditis, and rheumatic fever. The diagnosis is based on history, clinical findings, ECG, specific provocative tests and, if necessary, long-term ECG monitoring. The sick sinus syndrome is most frequently seen in patients aged over 50 years. Treatment with drugs alone, such as atropin, catecholamines, digitalis or antiarrhythmic drugs is often difficult becuase of the frequent changes between bradycardic and tachycardic arrhythmia. In chronic and progressive cases, the best treatment is implantation of a cardiac pacemaker.
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PMID:[Sinus node syndrome]. 100 72

The authors describe the results of studying the anti-inflammatory effect of indomethacin in 102 young men suffering from acute rheumatic fever (ARF). It has been shown that indomethacin has a remarkable anti-inflammatory effect both on the general disease manifestations and on the basic symptoms. For instance, in ARF patients, fever disappeared on days 2-4 of the treatment whereas the signs of arthritis on days 7-8 of the treatment, on the average. Besides, indomethacin produced a marked analgesic effect, since in 84% of the patients, arthralgias diminished on days 2-3 from the onset of indomethacin treatment. Practically, in all the patients, they disappeared simultaneously with arthritis phenomena. Disorders of rhythm and conduction also disappeared on days 2-4 from the treatment onset, while the end part of the ventricular complex returned to normal a little bit later (days 13-15). Subjective symptoms of rheumocarditis disappeared completely by the end of the treatment. Within the same time, dynamic mesodiastolic murmur and additional sounds also disappeared, the deadening of sounds noticeably decreased, the intensity of systolic murmur declined. The overwhelming majority of the patients demonstrated normalization of the heart size. Side effects were recorded in 11 patients. They were largely arterial hypertension, epigastric pains, dizziness and headaches which disappeared as a result of corrective therapy and a short-term reduction of the indomethacin dose.
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PMID:[The results of the indomethacin treatment of patients with acute rheumatic fever]. 180 12

We studied six patients with atrial myxoma, 5 occurred in left atrium and one in the right atrium, the diagnosis was verified with echocardiogram and surgery, we determined the clinical, electrocardiographic and radiological differences between the mitral stenosis and myxoma. We found that patients with atrial myxoma have no history of rheumatic fever, the dyspnea was less severe of shorter and duration, patient had paroxysmal dyspnea. In contrast dizziness, faintness, hemiparesis and/or angina were the more frequent symptoms. A diastolic mitral snap was a very frequent finding, less frequent was the diastolic rumble no patient had pre-systolic murmur. The left atrium was generally not dilated and the left atrial appendage as well as the pulmonary artery were not prominent in chest X-Rays. The P wave in lead II was not more than 0.11 sec and the ventricular complex in VI did not show tall R ware. With the previous elements it is possible to suspect the diagnosis of left atrial myxoma. The diagnosis should, of course, be confirmed by echocardiography.
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PMID:[Clinical diagnosis of left auricular myxoma based on its echocardiographic and surgical verification]. 295 58