Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0012833 (dizziness)
 9,689 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An overview of the literature shows that shift work is linked with an enhanced risk of psychiatric disorders. A number of authors have reported anxious and depressive symptomatology in shift workers, but there are no data about the frequency of somatoform disorders associated with this type of work. Psychosocial stress and low socio-economic status, both often found among shift workers, are regarded as risk factors for somatoform disorders. The connection of shift work and somatoform disorders is discussed with examples of four case reports. It is suggested that shift work, which is known to be associated with an increased incidence of cardiovascular diseases, may promote the occurrence of vegetative symptoms, such as feelings of weakness and dizziness, and eventually leads to intensified self-observation, anxiousness and hypochondriasis with predominantly somatic symptoms.
 ...
PMID:[Effect of shift work on somatoform disorders]. 157 40

We report a case of 68-year-old woman who was diagnosed spinocerebellar ataxia type 6 (SCA 6) by genomic testing. She presented hypochondriasis, parkinsonism, and ataxia. Since the age of 60, she noted difficulty in walking due to dizziness, and MRI showed minimal cerebellar atrophy. She became unable to walk without assistance at the age 67. She was referred to us when she was 68 years old. She had no family history of cerebellar ataxia, and her general physical examination was normal. Her speech was fluent, with neither slurring nor scanning, and she complained of much anxiety regarding her physical condition and was diagnosed as having hypochondriasis. Neurological examination revealed parkinsonism consisting of small steppage gait, mask-like face, akinesia, rigidity of neck and limbs, and postural instability. She also showed cerebellar signs such as saccadic smooth pursuit, ataxia of upper and lower limbs, and increased tendon reflexes. Her parkinsonism had developed slowly and symmetrically yet she showed a lack of response to levodopa. Our results suggest that the genomic testing is useful for differential diagnosis for the diseases presenting ataxia and parkinsonism, even if the family history is negative.
 ...
PMID:[A case of spinocerebellar ataxia type 6 with hypochondriasis and severe parkinsonism]. 1180 19

Bodily symptoms and utilization of medical care. OBJECTIVE: An important aspect in a person's attitude towards disease, which also determines when medical help is sought, relates to one's perception of bodily symptoms and to the manner in which the impact of an illness is dealt with. It was the aim of this study to ascertain what bodily signs of disease in an organ system would make healthy persons within a normal population seek medical help. MATERIAL AND METHODS: A representative sample of the population of Germany (n=2050), aged between 14 and 92 years, was presented with the description of 20 symptoms of diseases of various organ systems and asked which of these symptoms would induce them to consult a doctor. RESULTS: Between 8% and 10% of those asked said that they would not go to a doctor even if they had clear bodily symptoms, e. g. blood in the urine , persistent joint pains , dizziness of fainting or pain in the lower abdomen . Analysis of variance for individual symptoms revealed that a significantly higher percentage of women and elderly persons would go and see a doctor than men and younger persons. Significantly fewer persons in the eastern (former DDR) Lands than the western ones would seek medical help. There was no significant correlation between the seeking medical help and subjective complaints, as measured by the Giessen Complaint Questionnaire, as well as any tendency towards hypochondria, as measured by the Whiteley Hypochondria Index. CONCLUSION: It is clear that complex processes of bodily awareness and assessment of symptoms precede medical consultation. These processes must be considered as part of a person's attitude towards illness and, most of all, of its congnitive component ( health beliefs ). They are dependent on charakteristics of sociodemography and social structure ant they have far reaching significance for ambulatory care. It is clear that there is a great need for research in this area.
 ...
PMID:[Bodily symptoms and utilization of medical care] 1275 Oct 21

This study was designed to study patients with intolerance to pesticide smells. Ten subjects chosen were complaining of vague symptoms such as headache, dizziness, fatigue, nausea, vomiting, abdominal pain, myalgia, flu-like symptoms, etc., whenever exposed to the pesticide smells even at low intensity. To determine whether the etiology of this kind of pesticide hypersensitivity was of organic or psychiatric nature, all the subjects underwent tests as follows: complete blood cell count, urinalysis, and blood chemistry as routine tests; esophogastroduodenoscopy and abdomen ultrasonography for the gastrointestinal symptoms; chest x-ray, pulmonary function tests, and electrocardiography for the respiratory and/or cardiac symptoms; nerve conduction velocity and brain magnetic resonance imaging (MRI) for peripheral and central nerve system symptoms; and K-WAIS, Rey-Kim memory test, Rorschach, Mini Mental State Examination (MMSE), and Minnesota Multiphasic Personality Inventory (MMPI) for psychoanalysis. Of the 10 cases in which the chief complaint was headache, symptoms of two cases were caused by maxillary sinusitis. Another two showed typical multiple chemical sensitivity (MCS) or idiopathic environmental intolerance (IEI). Six out of the 10 cases, whose symptoms closely resembled the others, did not conclusively meet the criteria of classic MCS or IEI. The subjects of this case shared vague fears, both fear of pesticides and hypochondriasis. Some subjects faced financial insecurity and social uncertainty; others felt uneasy about the future of their farming life. Thus, to help verify the causes of MCS or IEI, which is strongly suggestive of pesticide smells, diagnosis needs a dual approach: on the anima and soma. Psychoanalysis can delve into the mental status of the patients to see whether the patients are aware of their symptoms. Clinical tests can see through the physical structure and functions of the organs on which patients' complaints are centered.
 ...
PMID:Pesticide-initiated idiopathic environmental intolerance in South Korean farmers. 1749 36