Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0012739 (disseminated intravascular coagulation)
 8,673 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
DIC 1713
fibrinogen 1163
thrombin 817
prothrombin 628
Sep 555
thromboplastin 524
antithrombin III 426
antithrombin 342
She 342
tissue factor 319
protein C 307
thrombomodulin 251
FDP 189
plasminogen 176
lipopolysaccharide 156
cytokine 135
PLA 127
factor VIII 103
hemoglobin 89
factor VII 88
VIII 84
all-trans 82
protein S 80
plasminogen activator inhibitor-1 78
plasminogen activator inhibitor 77
tumor necrosis factor 76
factor Xa 73
von Willebrand factor 71
tissue factor pathway inhibitor 70
collagen 69
LPS 66
factor V 63
IL-6 62
albumin 62
urokinase-type plasminogen activator 60
Antithrombin III 60
tissue plasminogen activator 59
C-reactive protein 56
Mol 55
TNF 53
Protein C 53
fibronectin 50
MRI 46
alpha 2-plasmin inhibitor 45
lactate dehydrogenase 44
kallikrein 44
ferritin 42
protease inhibitor 42
Pol 41
CO2 41
interleukin-6 40
LDH 40
Prothrombin 40
AML 39
vascular endothelium 39
serine protease 38
SARS 36
TAT 36
ADP 35
glycoprotein 35
bradykinin 34
alkaline phosphatase 33
Pseudomonas 33
interferon 32
serum albumin 32
insulin 31
thrombin inhibitor 30
alanine aminotransferase 30
creatine kinase 29
lymphoid 29
FAB 29
platelet factor 4 28
SDS 28
Thrombomodulin 28
TNF-alpha 27
factor XII 27
ADAMTS13 27
hemophilia A 26
myoglobin 26
chronic renal failure 26
aspartate aminotransferase 25
esterase 25
L-asparaginase 23
ATP 23
Antithrombin 23
Factor VIII 23
factor IX 22
granulocyte 22
factor XI 21
myeloperoxidase 21
IL-8 21
serine protease inhibitor 21
CRP 21
ALL 21
beta-thromboglobulin 20
IL-10 20
Plasminogen 20
white cell 19
mucin 19
peroxidase 19
HLA 19
APL 18
C1 inhibitor 18
CSF 17
lectin 17
neutrophil elastase 17
plasma protein C 17
FVIII 17
axonal 17
amylase 17
GPT 16
thrombin-activatable fibrinolysis inhibitor 16
endoplasmic reticulum 15
heparin cofactor II 15
promyelocytic leukemia 15
polypeptide 15
PAI 15
alpha 1-antitrypsin 15
ABO 15
haptoglobin 15
Hageman factor 14
oxytocin 14
ACTH 14
NO3 14
granulocyte colony-stimulating factor 13
PML 13
Mal 13
CD8 13
CD4 13
TTP 13
Plasmin 13
Gen 13
IL-1 beta 13
trypsin inhibitor 13
NMR 13
IFN 13
kit 13
CD33 12
thrombopoietin 12
vWF 12
tyrosine kinase 12
IL-1 12
Protein S 12
HUS 12
PCI 12
HLA-DR 12
MOF 12
IgA 12
XDP 11
factor V Leiden 11
Rec 11
interleukin 6 11
vasopressin 11
reserved 11
CD56 11
thymus 11
AST 11
prostate-specific antigen 11
alpha2-macroglobulin 11
rhabdomyosarcoma 11
more...
Disease
disseminated intravascular coagulation 8673
sepsis 1228
sepsis 1094
thrombocytopenia 900
coagulopathy 676
cancer 600
tumor 389
acute renal failure 325
renal failure 320
acute promyelocytic leukemia 264
anemia 240
leukemia 235
pneumonia 212
purpura 208
adult respiratory distress syndrome 198
hypertension 162
cirrhosis 155
stroke 151
hemolytic anemia 149
liver disease 149
thrombocytopenic purpura 145
acute myeloid leukemia 144
preeclampsia 142
deep vein thrombosis 133
carcinoma 132
respiratory failure 131
diabetes 126
coma 124
systemic lupus erythematosus 120
hepatitis 115
metastases 114
pulmonary embolism 108
endocarditis 106
lymphoma 105
infectious diseases 104
rash 104
ischemia 101
vasculitis 98
pulmonary edema 98
hypofibrinogenemia 97
encephalopathy 97
heart failure 96
HELLP syndrome 95
malaria 93
adenocarcinoma 92
gastric cancer 92
eclampsia 90
gangrene 90
acute leukemia 89
bacteremia 87
myocardial infarction 86
hemangioma 80
pancytopenia 77
hemolytic uremic syndrome 77
pancreatitis 75
depression 73
acute lymphoblastic leukemia 69
virus infection 68
abortion 68
meningitis 67
haemophilia 66
fits 65
hemorrhagic diathesis 64
Purpura fulminans 63
hypoglycemia 63
lupus 62
abruptio placentae 61
KMS 60
acute pancreatitis 58
prostate cancer 58
petechiae 56
tuberculosis 56
peritonitis 55
uterus 53
leukopenia 53
influenza 53
renal insufficiency 52
SARS 52
proteinuria 52
lupus 51
aortic aneurysm 50
antiphospholipid syndrome 50
toxic shock syndrome 50
ARF 49
varicella 49
cerebral infarction 49
Haemophilia 48
acute myocardial infarction 47
abdominal aortic aneurysm 47
carcinomatosis 47
dehydration 46
vitamin K deficiency 45
hepatocellular carcinoma 44
dengue 43
Shwartzman reaction 43
Infection 42
confusion 42
bacterial infection 42
idiopathic thrombocytopenic purpura 40
lymphadenopathy 40
renal disease 40
atherosclerosis 39
hemorrhagic fever 37
Klebsiella 37
neutropenia 37
fatty liver 36
hematologic malignancies 35
bone metastases 35
myocarditis 35
Amniotic fluid embolism 35
toxemia 35
lung cancer 35
glomerulonephritis 35
congestive heart failure 34
hemophagocytic lymphohistiocytosis 33
endotoxic shock 33
Amniotic fluid embolism 33
cold 32
rheumatoid arthritis 32
Thrombus 32
angiosarcoma 32
thrombocytosis 32
cytomegalovirus 31
Hodgkin's disease 31
compartment syndrome 31
immunodeficiency 30
chronic renal failure 30
nephrotic syndrome 30
SDS 29
fasciitis 29
pyelonephritis 29
meningococcemia 29
chronic myeloid leukemia 29
TTP 28
anaphylaxis 28
von Willebrand disease 28
arthritis 28
anuria 28
hyperbilirubinemia 28
prematurity 27
rare disease 27
pulmonary hypertension 27
Epstein 27
azotemia 26
portal hypertension 26
aggression 26
multiple myeloma 26
breast cancer 25
AIDS 25
acute tubular necrosis 25
Plasmodium falciparum malaria 24
encephalitis 24
esophageal varices 24
cholestasis 24
subarachnoid hemorrhage 24
heart disease 23
hemangioendothelioma 23
acute hepatitis 23
primary tumor 23
nephritis 23
more...
Symptom
respiratory distress 225
diarrhea 127
abdominal pain 120
pain 119
vomiting 112
seizures 94
dyspnea 92
headache 85
collapse 85
anesthesia 75
splenomegaly 72
hypothermia 61
fatigue 60
hepatosplenomegaly 59
nausea 56
anorexia 50
weakness 43
hepatomegaly 41
cough 39
oliguria 38
Ill 36
back pain 29
cyanosis 28
erythema 28
low back pain 27
myalgia 26
lethargy 26
chills 24
tachypnea 20
bone pain 18
hemiplegia 17
sore throat 17
chest pain 17
consciousness disturbance 16
fever of unknown origin 14
nausea and vomiting 14
hemoptysis 13
shortness of breath 13
exhaustion 13
intestinal bleeding 13
epigastric pain 13
ataxia 12
polyuria 12
agitation 11
hypoproteinemia 11
dizziness 11
tremor 11
pallor 10
sleepiness 10
regurgitation 9
muscle rigidity 9
arthralgia 9
angina 8
analgesia 8
acute abdomen 8
cerebellar ataxia 8
right upper quadrant pain 8
flushing 7
leg pain 7
spasm 7
exertional dyspnea 7
abdominal discomfort 7
discomfort 7
dysarthria 7
paresis 7
cachexia 6
discomfort 6
productive cough 6
neck stiffness 6
colic 6
asthenia 5
tonic-clonic seizure 5
polydipsia 5
paresthesia 5
abdominal fullness 4
flank pain 4
acute abdominal pain 4
vertigo 4
ENT 4
livedo 4
dark urine 4
rigors 4
photophobia 4
numbness 4
tense 4
dysuria 4
leg edema 4
tonic seizure 3
blurred vision 3
skin damage 3
hyperoxia 3
night sweats 3
hypotonia 3
rales 3
spasticity 3
hypercapnia 3
myoclonus 3
dysesthesia 3
functional recovery 3
localized edema 3
acidity 3
Wind 2
prostration 2
menometrorrhagia 2
hunger 2
autodigestion 2
hyperemesis gravidarum 2
abdominal cramps 2
neck pain 2
persistent cough 2
hip pain 2
paraparesis 2
thinning 2
giddiness 2
giddiness 2
stridor 2
syncope 2
anosmia 2
rhinorrhea 2
tinnitus 2
urinary frequency 2
Sedation 2
dental pain 2
wheezing 2
decreased appetite 2
hypertonia 2
emaciation 2
Mental status changes 1
retching 1
fasciculation 1
athetosis 1
generalized abdominal pain 1
loin pain 1
generalized erythema 1
orofacial pain 1
generalized rash 1
Intermittent fever 1
acute pain 1
Blanching 1
lightheadedness 1
Kernig's sign 1
clammy skin 1
overweight 1
hypocapnia 1
hyperesthesia 1
painful swallowing 1
labored breathing 1
Diarrhea and vomiting 1
orthopnea 1
monoplegia 1
pedal edema 1
left upper quadrant pain 1
inanition 1
pleuritic chest pain 1
generalized pain 1
apathy 1
CSR 1
chorea 1
starvation 1
clonus 1
more...
Drug
Antithrombin III 62
Cardiovasc 50
Dermatol 49
TAT 36
Gabexate mesilate 24
ampicillin 23
CSF 19
lysine 18
Ancrod 16
Dial 15
Aprotinin 13
LMWH 12
MOF 12
PTC 10
NovoSeven 10
uPA 9
G-CSF 9
vitamin E 8
IFN-gamma 8
Rituximab 8
Nafamostat mesilate 7
Nephron 6
ACT 6
Nephron 6
nitroglycerin 6
Adriamycin 6
MDS 5
ENT 5
Acyclovir 5
CTX 5
Vitamin K 5
Argatroban 5
Leaf 5
Vitamin B12 5
Urokinase 4
CTC 4
Gelfoam 4
CTC 4
Serum albumin 4
AraC 4
Fragment 4
MAP 4
ROC 4
Prednisolone 4
Spectrum 4
Gel 4
CPR 4
IL-2 4
Batroxobin 3
caffeine 3
Doxycycline 3
Ketoconazole 3
DMAP 3
MINO 3
Salicylate 3
Heme 3
Coumadin 3
ROS 3
Phentolamine 3
Drotrecogin alfa 3
AIC 3
Oseltamivir 3
DDAVP 3
Oxaliplatin 3
HCG 3
CPT-11 3
Drotrecogin alfa 3
Campath 2
citric acid 2
Methylprednisolone 2
Filgrastim 2
Asthma 2
Fragmin 2
Idarubicin 2
Asn 2
Thrombostat 2
Fansidar 2
Primaquine 2
Hypaque 2
Ginseng 2
Atropine 2
DDAVP 2
Ceftazidime 2
Fructose 2
CaCl2 2
Fansidar 2
Campath 2
Phosphatidylserine 2
CaCl2 2
CaCl2 2
Isotretinoin 2
anti-CD33 2
Fondaparinux 2
Tuberculin 2
IL-1ra 2
Fluorescein 2
MEPM 2
THF 2
Orgaran 2
Filgrastim 2
Arsenic trioxide 2
Atenolol 2
Abciximab 2
Antithymocyte globulin 2
Magnesium sulfate 2
SrCl2 2
Ulinastatin 2
Thrombomodulin alfa 2
AHF 2
DFP 2
L-Asparaginase 2
Streptokinase 2
Fluorescein 2
Vitamin E 2
Quinine, 2
Ethanol 2
Theophylline 2
Eculizumab 2
Methyldopa 2
Bayer 2
CTA 2
Ranitidine 2
IPD 1
Amoxicillin 1
LMOX 1
CAZ 1
Thioguanine 1
lactose 1
Ethyl icosapentate 1
Misoprostol 1
Apixaban 1
Isopaque 1
CZX 1
CTX 1
AZT 1
RFP 1
CFT 1
Gleevec 1
Meropenem 1
EHDP 1
Aclarubicin 1
Iohexol 1
CPM 1
ABC 1
Ipilimumab 1
NAG 1
NADH 1
CDP 1
Cetrorelix 1
Sulprostone 1
Monit 1
Coral 1
Phenprocoumon 1
MgSO4 1
EE2 1
TiO2 1
TAK 1
Anakinra 1
Methergine 1
CEC 1
more...
Enzyme
thrombin 785
thromboplastin 571
APC 394
plasmin 232
tissue plasminogen activator 122
urokinase-type plasminogen activator 65
kallikrein 56
alanine aminotransferase 55
lactate dehydrogenase 54
creatine kinase 40
peroxidase 39
aspartate aminotransferase 38
elastase 37
TAT 36
alkaline phosphatase 33
asparaginase 31
trypsin 29
neutrophil elastase 26
ancrod 22
ERK 17
phospholipase A2 15
Hageman factor 15
thrombin-activatable fibrinolysis inhibitor 13
AST 11
lysozyme 10
CD13 10
prostate-specific antigen 10
superoxide dismutase 9
CFI 9
acid phosphatase 9
cholinesterase 9
lipase 9
carbonic anhydrase 9
mitogen-activated protein kinase 8
renin 8
cancer procoagulant 8
hyaluronidase 7
ACE 7
chymotrypsin 7
phospholipase C 6
beta-lactamase 6
collagenase 6
hyaluronidase 6
protein kinase C 5
CD10 5
NO synthase 5
catalase 5
cathepsin B 5
acetylcholinesterase 5
angiotensin-converting enzyme 2 5
ATPase 5
reverse transcriptase 5
ACS 4
proteasome 4
tryptase 4
CPR 4
focal adhesion kinase 3
transcriptase 3
meprin 3
heme oxygenase 3
monoamine oxidase 3
glucose-6-phosphate dehydrogenase 3
neuraminidase 3
caspase-3 3
gamma-glutamyl transpeptidase 3
PTA 3
heparinase 3
kinesin 3
MDP 3
PPH 3
MAP 3
NOS 3
granzyme B 3
thymidine kinase 2
apyrase 2
clotting enzyme 2
lactic acid dehydrogenase 2
glyceraldehyde-3-phosphate dehydrogenase 2
ornithine transcarbamylase 2
glyceraldehyde-3-phosphate dehydrogenase 2
adenosine deaminase 2
transglutaminase 2
tissue kallikrein 2
uricase 2
lactic acid dehydrogenase 2
glutathione peroxidase 2
RNA polymerase 2
demethylase 2
glyceraldehyde-3-phosphate dehydrogenase 2
alcohol dehydrogenase 2
GAS 2
hepsin 2
carboxylesterase 2
glyceraldehyde-3-phosphate dehydrogenase 2
lactic acid dehydrogenase 2
luciferase 2
adenosine deaminase 2
carboxypeptidase B 2
subtilisin 2
hepsin 2
protein kinase 2
beta-glucuronidase 2
cathepsin D 2
CPN 2
ADH 2
glyceraldehyde-3-phosphate dehydrogenase 2
caspase-1 2
DNA polymerase 2
glutamate dehydrogenase 1
glutamate dehydrogenase 1
CPM 1
nitrate reductase 1
lysophospholipase D 1
xanthine oxidase 1
sphingomyelinase D 1
glutamate dehydrogenase 1
indoleamine 2,3-dioxygenase 1
sorbitol dehydrogenase 1
polo-like kinase 1 1
TGT 1
PARP 1
p80 1
coagulation factor VIIa 1
PME 1
chondroitinase 1
creatinase 1
peroxiredoxin 1
chondroitinase 1
rubisco 1
beta-1,3-glucanase 1
phospholipase D 1
nitrate reductase 1
naphthalene dioxygenase 1
dihydropyrimidine dehydrogenase 1
DD-carboxypeptidase 1
AMPK 1
TdT 1
phosphoinositide 3-kinase 1
matrix metalloproteinase 9 1
cathepsin G 1
hexosaminidase 1
PST 1
histone acetyltransferase 1
MAT 1
AMP-activated protein kinase 1
NAO 1
adenylate cyclase 1
complex I 1
p100 1
beta-galactosidase 1
beta-1,3-glucanase 1
methylenetetrahydrofolate reductase 1
MDR 1
PCP 1
C1 esterase 1
guanylate cyclase 1
C3 convertase 1
MAT 1
enolase 1
CPT 1
more...
Compound
DIC 1713
Clin 676
Dec 556
FDP 189
water 184
oxygen 148
sodium 127
Heparin 112
creatinine 106
retinoic acid 102
His 98
DNA 95
calcium 90
Fibrinogen 88
sulfate 86
Fibrin 77
nitrogen 72
carbonate 71
Thrombin 71
urea 68
ethanol 62
CO2 61
glucose 60
TNF 53
ADP 47
arginine 45
TEM 44
prostacyclin 39
DOC 39
ADP 37
acetate 36
iron 36
serine 35
ADP 35
nitrate 34
SDS 32
nitric oxide 32
phosphate 27
lysine 25
Cardiol 23
ATP 23
methane 22
hydrogen 21
alanine 20
HCO 20
EDTA 19
salt 19
ammonium 18
Phe 18
Warfarin 17
potassium 17
galactose 16
5-FU 16
GPT 16
EDTA 15
tyrosine 15
Factor X 15
Dial 14
TTP 13
methionine 13
NO3 13
acetic acid 13
prostaglandin E1 12
PEG 12
Gly 12
Asp 12
Plasmin 12
ACS 11
zinc 11
Carbon 11
silver 11
leucine 11
cysteine 10
PEG 10
A 71 10
ALP 9
ammonia 9
Fibrinopeptide A 9
copper 9
iodine 9
GSH 9
ACTH 9
GSH 9
A 42 9
ASA 9
TEG 9
PAP 8
MTX 8
Ara-C 8
methanol 8
PAP 8
NH2 8
PAP 8
Adriamycin 8
DEAE 8
PAP 8
Optimal 8
Methotrexate 8
phosphorus 8
Methicillin 7
sulfuric acid 7
H2O2 7
formaldehyde 7
Isoproterenol 7
cAMP 7
CAM 7
barium 7
THP 7
Morphine 7
mercury 7
DHF 7
threonine 7
Quinine 7
A 3 7
noradrenaline 7
proline 6
Vitamin K 6
2-hydroxyethyl 6
THP 6
strontium 6
acridine 6
CAP 6
Dextran 6
MDA 6
Ile 6
A 1 6
nicotinic acid 5
aldosterone 5
Guo 5
GTP 5
Ara-C 5
formaldehyde 5
DBA 5
prostaglandin F2alpha 5
Diclofenac 5
salicylic acid 5
Guo 5
DMSO 5
CTX 5
homocysteine 5
Vincristine 5
benzene 5
DBA 5
2-oxoglutarate 5
vinyl 5
Tranexamic acid 5
TXA2 5
VP-16 5
nicotinic acid 5
Argatroban 5
Acyclovir 5
Neuronal 5
Vancomycin 5
nicotinic acid 5
DSS 5
DBA 5
APAP 5
nicotinic acid 5
dichloromethane 4
6-Mercaptopurine 4
more...