Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0012739 (disseminated intravascular coagulation)
 8,673 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Consideration is given to time course changes in microcirculatory bed, hemostasis and fibrinolysis in patients with acute NPD and the trend of these changes upon autotransfusion of blood exposed to UV radiation. The doses of the blood varied. It was found that acute phase of the disease is characterized by impairment of hemostasis and fibrinolysis typical for DIC-syndrome. The autotransfusion promoted activation of fibrinolysis, hypocoagulation tendency, reduction of perivascular edema and sludge of red blood cells. Less beneficial effect was observed for the blood dose range of 1.5-2.0 ml/kg manifesting a transitory tendency to hypercoagulation and enhancement of erythrocytic sludge resulting in clinical aggravation in the middle of the treatment course. The highest response occurred in the dose range of 0.7-1.0 ml/kg which is proposed for management of NPD sufferers.
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PMID:[Dynamic microcirculatory disorders in patients with nonspecific lung diseases during the autotransfusion of ultraviolet-irradiated blood]. 281 44