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Query: UMLS:C0012739 (disseminated intravascular coagulation)
 8,673 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Prolonged hypotension and disseminated intravascular coagulation were seen in a patient after intravasation of barium sulfate contrast medium during a barium enema examination. High endotoxin levels were measured in the contrast material. In vitro, this material induced generation of bradykinin. The clinical features observed may be explained by contact activation of the Hageman factor-dependent pathways caused by the contrast material and/or by circulating endotoxins. Treatment of this rare but severe complication occurring during a barium enema procedure should be directed against the endotoxic shock.
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PMID:Disseminated intravascular coagulation and hypotension after intravasation of barium. 686 54

From the viewpoint of fetal distress related disseminated intravascular coagulation (DIC), the Hageman Factor, kinin-kallikrein system were investigated and on the other hand the adaptation of the normal newborn to extrauterine life was also evaluated. (1) The Kininogen volume of the cord venous blood was approximately 1/2-1/3 or there abouts and was remarkable in serious cases of asphyxiated newborn. (2) In a similar manner the Hageman factor decreases in asphyxiated newborn. On the other hand, SFMC increases in aspyxiation as well as FDP. According to these results, there seems to be a coagulation obstruction due to consumption. Or it may be interpreted as an inhibition of kinin separation. In any event it may be considered as a rational contribution to the living body. (3) Based on the above, in cases of serious asphyxiation, DIC may possibly play a role and in these cases and the kininkallikrein system may be one of the mediators.
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PMID:A biochemical study on the kinetics of kininogen in asphyxiated newborn. 706 58

The hemostasis system was studied in 31 pregnant women with Fallot's tetralogy, aged 18 to 32. In women with a history of radical correction of this condition a subcompensated form of the DIC syndrome was detected, manifesting as chronometric and structural hypercoagulation and platelet hyperaggregation. In patients with the cyanotic form of Fallot's tetralogy hypocoagulation thrombophilia was revealed, that was due to deficiency of contact factors (Hageman factor, highly molecular kininogene) and that was responsible for thrombohemorrhagic complications in these patients. Replacement therapy is recommended for such cases in labor and controlled anti-thrombotic therapy in the postpartum period.
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PMID:[The hemostatic system in pregnant women and puerperae with the tetralogy of Fallot]. 825 Jan 11

In accordance with the proposed methodics the state of Hageman factor (HF) system was studied, i.e. intimate connection of callicrein-kinine, coagulation and fibrinolytic blood systems in various clinic and hemostasiological forms of DIC-syndrome, acute and chronic arterial thromboses, thrombembolisms, post-operative and thrombolytic hemorrhages in 1118 patients. The author describes the principles of diagnosis, prophylaxis and correction of the disorders in blood coagulation, fibrinolysis and kinogenesis in this pathology. The article contains data concerning the structure of researches, index and HF coefficients, as well as reference hemostasiological criteria, classification and medical tactics in various forms of DIC-syndrome.
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PMID:[New principles in the prognosis, diagnosis, prevention and treatment of the DIC syndrome]. 857 10


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