Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0012739 (disseminated intravascular coagulation)
 8,673 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Endoscopic examination of a 35-year-old patient complaining of tarry stool, palpitation and lumbago led to a diagnosis of gastric cancer of Borrmann type 4. Laboratory data and bone scintigraphy revealed findings of DIC and multiple bone metastasis. He was treated with continuous intravenous infusion of FOY, but laboratory data with DIC went from bad to worse. It was considered that resection of the tumor was effective for DIC, then total gastrectomy and partial transverse colonectomy were performed, and the patient recovered from DIC. For the multiple bone metastasis, he received chemotherapy using cisplatinum and mitomycin C, and subsequent bone scintigraphy showed a dramatic improvement. Doxorubicin and 5-fluorouracil controlled peritoneal dissemination of the cancer.
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PMID:[Advanced gastric cancer with DIC and multiple bone metastasis treated with surgical resection and chemotherapy]. 310 31

A juxtaovarian tumor of probable mesonephric origin in an 18-year-old white woman recurred six years later with a pelvic mass and widespread peritoneal metastases. Chemotherapy with cyclophosphamide, Doxorubicin, and cis-platinum induced a partial response of approximately one year duration. The terminal disease course was associated with hypercalcemia and disseminated intravascular coagulation. At autopsy, there were extensive abdominopelvic tumor masses with pleural deposits.
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PMID:Metastasizing malignant juxtaovarian tumor with terminal hypercalcemia: a case report. 724 14