Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0012739 (
disseminated intravascular coagulation
)
8,673
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
New assays for thrombin-antithrombin III complex, plasmin-alpha 2-plasmin inhibitor complex, FDP-D-dimer, t-PA/PAI-1 complex and prothrombin fragment F1+2 are reviewed as molecular markers for
disseminated intravascular coagulation
(
DIC
). These are sensitive to early stage indication of
DIC
.
Fluctuation
of their levels was also relative to the state of
DIC
. It is therefore believed that they will play an important role in the diagnosis of
DIC
, as solid members of its parameter. On the other hand, t-PA/PAI-1 complex is suggested to be the complication marker of
DIC
, such as multiple organ failure (MOF), as its level was thought to reflect endothelial cell stimulation during
DIC
.
...
PMID:[New useful parameters or makers in diagnosis and condition. Analysis of disseminated intravascular coagulation--mainly molecular markers]. 843 26
