Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0012739 (
disseminated intravascular coagulation
)
8,673
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Symmetrical peripheral gangrene (SPG) is a rare syndrome associated with a multitude of underlying medical problems. We are adding three cases of SPG to the medical literature, all of which had
disseminated intravascular coagulation
(
DIC
). Each had an underlying illness that, to our knowledge, has not been previously associated with SPG: Hodgkin's lymphoma,
Escherichia coli urinary tract infection
with septicemia, and polymyalgia rheumatica. Review of the medical literature shows a high association between SPG and
DIC
. Symmetrical peripheral gangrene should therefore be considered a cutaneous marker of
DIC
. Early recognition and treatment of the underlying medical problem and
DIC
could be lifesaving.
...
PMID:Symmetrical peripheral gangrene and disseminated intravascular coagulation. 389 58
