Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0012739 (disseminated intravascular coagulation)
 8,673 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Amyopathic dermatomyositis (ADM) is a variant of dermatomyositis that is characterized by the typical skin rash but without the muscle abnormalities. We report a case of ADM complicated with interstitial pneumonitis (IP) and lung cancer. A 73-year-old female was hospitalized for skin rash and dry cough. Skin biopsy findings were compatible with dermatomyositis though no subjective and objective findings suggestive of skeletal muscle involvement were noted. Chest computed tomography (CT) revealed a consolidation of her right upper lung and irregular opacity of bilateral lower lobe. By histopathological evaluation, she was diagnosed as lung cancer with ADM. Therapy consisting of prednisone was begun. Two weeks after the surgery, dry cough progressed. Her acute exacerbation of IP did not respond to the therapy and passed away by disseminated intravascular coagulation and respiratory failure.
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PMID:[Post-operative acute exacerbation of interstitial pneumonea associated with amyopathic dermatomyositis]. 2066 33