Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0012739 (disseminated intravascular coagulation)
 8,673 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The state of microcirculation and blood rheology was studied in 32 patients with chronic renal insufficiency. Improved microcirculation and the reduction of clinico-laboratory indices of the DIC-syndrome were noted against a background of heparin and antiaggregant therapy in patients on programmed hemodialysis as well as in patients receiving systemic conservative therapy. In both groups of patients blood pressure decreased in parallel with a decrease in the level of creatinine and urea; a tendency toward improved renal function was noted.
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PMID:[Correction of blood rheological disorders in patients with chronic kidney failure using heparin and antiaggregants]. 317 33

A total of 29 patients with chronic renal insufficiency (CRI) were investigated. Noticeable disorder of erythrocytic deformability (ED) was detected in half of them. The expression of arterial hypertension showed correlation with a degree of ED disorder. A possibility of the main role of ED disorder in the development and progression of arterial hypertension was discussed. ED disorder was found to correlate with a degree of expression of laboratory signs of the DIC-syndrome and was practically unassociated with the blood level of creatinine.
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PMID:[Relation between arterial hypertension and disorder of erythrocyte deformability in patients with chronic renal failure]. 320 74

The authors discuss the causes of the DIC syndrome in urological patients operated on for urolithiasis. They enumerate the factors predisposing to the DIC syndrome and causing it. The predisposing factors are chronic renal insufficiency and metabolic disorders caused by azotemia, infectious inflammatory complications of urolithiasis, and intoxication. The causes of the disease are massive blood loss involving disorders of the hemodynamics and blood rheology, bacterial shock, and other stress conditions. A protocol for treating this complication and validation of pathogenetic therapy is offered.
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PMID:[The DIC syndrome as a complication of the surgical treatment of urolithiasis in urology patients]. 938 29