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Query: UMLS:C0012739 (disseminated intravascular coagulation)
 8,673 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a case of acute disseminated intravascular coagulation (DIC) developed during menstruation in an adenomyosis patient. No known predisposing factor for DIC such as infection or pregnancy was involved in this case. As anticoagulation therapy and supplementation of coagulation factors quickly improve the state, surgical removal of the uterus was not required. We speculate that hemorrhage in the adenomyosis legion and subsequent local thrombosis played crucial role in pathophysiology of this case of acute DIC.
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PMID:Acute disseminated intravascular coagulation developed during menstruation in an adenomyosis patient. 1243 60

We present a casuistic revision of adrenal pathology, which was studied in our service during the period January 1977-July 2000. We reviewed 59.069 biopsies and 2.674 autopsies and we 84 cases. founded with the following findings: Primary tumors 25% Secundary tumors 51% Infectious diseases 11% Miscellaneous 12% Unsuitable for diagnosis 1% Hyperplasias, adenomas, pheochromocy-tomas, neuroblastoma, adenocarcinoma are included within primary tumors. The metastasic tumors corresponded to: lung, pancreas, mammary gland, kidney and carcinomas; endometrial adenocarcinoma, lymphoma, melanoma, hepatocarcinoma, gastric carcinoma, testicular teratocarcinoma, skin epidermoid carcinoma, uterus choriocarcinoma and a primary germinal tumor of the thymus. Within infectious diseases we founded tuberculosis, histoplasmosis, cryptococosis, hydatidosis. Miscellaneous included hematoma, hemorrhage, pseudocyst, Disseminated Intravascular Coagulation (DIC), athrophy, Wegener's granulomatosis, myelolipoma, hemorrhagic necrosis. There was only one case which was unsuitable for diagnosis due to insufficient material.
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PMID:[Casuistic revision of adrenal pathology during last 23 years]. 1293 68

Uterine rupture is an unexpected, relatively uncommon occurrence in the general obstetric population, but it is a potentially devastating complication. Uterine rupture of the unscarred uterus is extremely rare. Awareness of the risk factors as well as the signs and symptoms of uterine rupture are essential for an early diagnosis and prompt treatment. The patient is a 38-year-old female, gravida 3, para 0, at 38 weeks' gestation undergoing an elective labor induction. The induction of labor and epidural analgesia progress relatively uneventfully. Following approximately 1.5 hours of "pushing," a viable male infant was delivered. Newborn Apgar scores were 6 at 1 minute and 9 at 5 minutes. An hour after delivery the patient began complaining of syncope; at this time bleeding was greater than expected and the obstetrician decided a dilatation and curettage for retained placenta was necessary. A dilatation and curettage was negative, and an ultrasound of the abdomen revealed the presence of significant blood clots, laparotomy was performed, and uterine rupture was identified. The patient developed disseminated intravascular coagulation, uterine bleeding continued, and the patient ultimately required a hysterectomy.
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PMID:Uterine rupture in a primigravid patient and anesthetic implications: a case report. 1462 72

Emergency caesarean section was performed in a 40-year-old woman with solutio placentae. A Couvelaire uterus was diagnosed, showing typical blue-purple discolorations of the uterine wall, which are in fact haemorrhages caused by disseminated intravascular coagulation.
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PMID:[Diagnostic image (213). A pregnant woman with premature contractions and vaginal blood loss]. 1555 11

Unrecognized phaeochromocytoma during pregnancy is dangerous for both fetus and mother. We report here a case of phaeochromocytoma crisis in Sipple's syndrome associated with disseminated intravascular coagulation that developed following intrauterine death. Early evacuation of the uterus seems advisable, to rid the patient with phaeochromocytoma of further complications associated with fetal death.
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PMID:Phaeochromocytoma crisis in Sipple's syndrome with intrauterine death and disseminated intravascular coagulation. 1563 49

The instability of the gestational and puerperal equilibrium of haemostasis is affected by a shift of primary and plasmatic haemostasis in a procoagulatory direction, whereas the regulation mechanism of the fibrinolytic system can easily cause disproportional peri- and postpartal reaction leading to massive haemorrhage. Peripartal injuries or an atonic uterus can lead to massive haemorrhage and cause a classic haemorrhagic coagulopathy. Complications like amniotic fluid embolism, puerperal sepsis, eclampsia or HELLP syndrome can lead through DIC to rapidly developing and possibly fulminant hyperfibrinolysis. This article depicts different forms of haemorrhage in the peripartal situation, their particular pathologies and specific possibilities for management. A case study demonstrates the diagnostic and therapeutic options in the case of eclampsia with early abruption of placenta.
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PMID:[Haemorrhagic complications in obstetrics]. 1695 94

A 51-year-old woman with adenomyosis was admitted because of anemia with schistocytosis, thrombocytopenia, and acute renal failure (ARF). Thrombotic microangiopathy (TMA) was considered. Plasma exchange and steroid therapies improved laboratory results. However, renal biopsy specimen revealed acute tubular necrosis (ATN), but not TMA, and thrombocytopenia, diagnosed it as disseminated intravascular coagulation (DIC) but not TMA. Few cases of DIC associated with benign tumors of the uterus and, especially, adenomyosis have been reported. In adenomyosis patients, ARF is usually caused by obstructive uropathy. However, the rare case suggests that hemolytic anemia, DIC, and ARF due to ATN can occur in adenomyosis patients.
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PMID:A case of anemia with schistocytosis, thrombocytopenia, and acute renal failure caused by adenomyosis. 2200 63

Placenta percreta were traditionally managed by immediate hysterectomy. Between 2004 and 2010, eight suspected cases of placenta previa accreta/percreta at our unit have been managed in a standardised way, with a plan to leave the placenta in situ if it does not separate easily. The placenta was removed with minimal difficulty in three cases. In two cases of percreta without bladder invasion, hysterectomy was performed with the placenta still attached to the uterus. In three cases of percreta with bladder invasion, the entire placenta was left in situ. In two of these cases, resolution occurred over an 8 and 12 month' period, respectively but in the third, the postoperative course was complicated by DVT and DIC. This patient then underwent hysterectomy with preoperative uterine artery embolisation, inferior vena cava filter placement and ureteric stenting. Conservative management is an attractive and safe alternative but careful patient selection and individualisation is needed.
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PMID:Planned conservative management of placenta percreta. 2266 16

A 35-year-old primigravida with severe ovarian dysfunction underwent in vitro fertilization with oocytes donated by her sister. A twin pregnancy ensued, and she received prenatal care at our hospital. She underwent a cesarean section at 35 weeks' gestation because of pregnancy-induced hypertension (PIH) and breech presentation at the onset of labor. Eclampsia with a generalized seizure occurred 5 hours after the cesarean section, while the patient was receiving medical treatment for disseminated intravascular coagulation secondary to an atonic uterus. Reversible posterior leukoencephalopathy syndrome (RPLS) was diagnosed with magnetic resonance imaging the following day. With control of the hypertension and seizures, the condition of the patient was stabilized, and the RPLS resolved several days later. Eclampsia and RPLS associated with pregnancy can be life-threatening and are typically closely related to PIH. Thus, this case illustrates that the risk of PIH is increased in pregnancies produced with donated oocytes.
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PMID:Reversible posterior leukoencephalopathy syndrome due to eclampsia in a woman with a twin pregnancy produced with donated oocytes. 2383 8

We reported a rare case of acute disseminated intravascular coagulation (DIC) after dilation and curettage in an adenomyosis and missed abortion patient. The clinical performance improved after treatment with tranexamic acid, blood transfusions and subtotal hysterectomy. Hemorrhage, degeneration and necrosis were found in the myometrium. Pregnancy-related thrombotic tendency, accelerated uterus tissue injury after curettage, activation of coagulation system, microthrombosis formation, myometrium necrosis, exhaustion of coagulation factors and hyperfibrinolysis might play the crucial roles in the pathophysiology of acute DIC. Physicians should be alert that adenomyosis patients undergoing dilation and curettage may be in danger of DIC.
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PMID:Acute disseminated intravascular coagulation developed after dilation and curettage in an adenomyosis patient: a case report. 2386 45


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