Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0012739 (disseminated intravascular coagulation)
 8,673 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases of consumption coagulopathy found in the patients having mitral stenosis with atrial thrombus were reported. In case 1, although anticoagulant (Warfarin) administration did not correct the hemostatic abnormality, combination of tranexamic acid with anticoagulant was effective. In case 2, atrial thrombus found in the echocardiography prior to the onset of thromboembolism in the lower limbs has been disappeared after embolism. Anticoagulant was effective for the improvement of hemostatic abnormality. We considered mitral stenosis with atrial thrombus as one of causes of the consumption coagulopathy.
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PMID:[Consumption coagulopathy found in mitral stenosis associated with atrial thrombus]. 276 73

We report a case of maternal mortality in a 34-year-old multipara who presented at the 35th week of gestation with severe hypoglycaemia. She had no history of diabetes mellitus. This episode was a prelude to catastrophic and refractory congestive cardiac failure due to previously undiagnosed severe mitral stenosis. The rapid cardiovascular deterioration initially appeared to be consistent with amniotic fluid embolism. She also developed deranged liver function with disseminated intravascular coagulation, which mimicked acute fatty liver of pregnancy. The problems of diagnosis and management are discussed. Unfortunately the patient died before mitral valvular commissurotomy could be effected.
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PMID:Severe mitral stenosis in a parturient with congestive cardiac failure and hypoglycaemia. 1532 Dec 12

Myxomas, as other primary cardiac tumors, appear rarely. The most common symptoms are typical of mitral stenosis or peripheral embolism. The rarity of infected cardiac myxomas leads to numerous diagnostic and therapeutic difficulties. We present a case of a 67-year-old man with fever of unknown origin. Laboratory results disclosed signs of sepsis, disseminated intravascular coagulation, acute renal failure, and neuroinfection. Blood cultures were positive for methicillin-resistant Staphylococcus aureus. Transthoracic echocardiogram revealed enlarged left atrium filled with tumor with mobile structure protruding into the left ventricle during diastole. Abnormal intra-atrial mass were also apparent in chest computed tomography (CT). Because of sepsis complicated by coagulation disorders, surgical treatment was postponed. On the 11th day, a large retroperitoneal hematoma occurred, and it was punctured under ultrasonography (USG) control. After 37 days of intensive medical therapy, a stable patient was operated. A giant tumor fixed to the atrial wall between the pulmonary veins' orifices was excised and confirmed as myxoma in histological tests. The patient was discharged in good condition and was followed up for several months with no further complications.
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PMID:Sepsis complicating giant cardiac myxoma. 1835 81