Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011881 (diabetic nephropathy)
 10,836 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
CTNNBIP1 protein 11.5
SET domain-containing protein 6 11.5
FLJ00279 11.5
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase 11.5
OR2L8 11.5
Eukaryotic translation initiation factor 4A, isoform 2 11.5
PP13439 11.5
ANKRD56 11.5
carnosinase 1 10.9
Engulfment and cell motility protein 1 10.5
SFRS15 10.5
LGP1 10.5
OR2AK2 10.5
bone morphogenic protein type II receptor 10.5
MIOX protein 10.5
CNDP1 10.4
ZNF236 10.2
UbA52 10.2
FRMD3 10.1
engulfment and cell motility 1 10.0
ALDR1 9.9
TCEAL6 9.9
MFAP3 9.9
TMEM212 9.9
hemicentin 1 9.9
IHG-1 9.9
Endosulfine alpha 9.9
C6orf167 9.9
forkhead box O4 9.7
TGFR-3 9.5
GPR149 9.5
Homeodomain interacting protein kinase 2 9.5
PLEKHH2 9.5
collagen, type IV, alpha 1 9.2
endothelial nitric oxidase synthase 9.2
TTC39C 9.2
APOL3 9.2
MAPK organizer 1 9.2
myosin, heavy chain 9, non-muscle 9.2
FAM101A 9.2
Small ubiquitin-like modifier 4 9.2
FEEL-2 8.9
GPR55 protein 8.9
ZNF230 8.9
OR2L13 8.9
FAR2 8.9
AKR1B1 protein 8.9
GPR120 protein 8.9
APOL2 8.9
cysteine knot protein 8.9
MYO16 8.8
megsin 8.8
nephrin 8.7
GPR153 8.7
UNC13B 8.7
ZO3 8.7
CGNL1 8.7
SMYD4 8.7
MEGF1 8.5
CNDP2 8.5
DNPEP 8.5
podocin 8.5
podocan 8.4
CAPN6 8.4
reticulon 1 8.4
upregulated in kidney 8.4
CLYBL 8.4
ATPIF1 8.4
col4a1 8.2
hexokinase III 8.2
FABP3 protein 8.2
50 AA 8.2
NADPH oxidase 5 8.2
SYNPO 8.2
GLIPR 8.2
MEP1B 8.2
laminin alpha 4 8.2
ELMO1 8.2
USAG-1 8.1
Nephrin 8.1
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Disease
diabetic nephropathy 11.5
Nodular diabetic glomerulosclerosis 11.5
Adult Fanconi syndrome 11.5
Renal failure and impairment 11.5
nephropathy; hereditary 11.5
Hypercholesterolemia aggravated 11.5
Chronic proliferative glomerulonephritis 11.5
Clinical diabetic nephropathy 10.9
Incipient diabetic nephropathy 10.9
Nodular glomerulosclerosis 10.4
Acute on chronic renal failure 9.9
GFND 9.9
Residual proteinuria 9.9
microalbuminuria 9.6
Microproteinuria 9.5
kidney hypertrophy 9.4
Segmental glomerulosclerosis 9.2
Hepatic calcification 9.2
von Willebrand disease type 2A 8.9
von Willebrand disease type 2A 8.9
hypertensive nephropathy 8.8
Immune complex glomerulonephritis 8.6
nephrosclerosis 8.6
Armanni-Ebstein lesion 8.5
Lipoatrophic diabetes 8.5
IDDM6 8.5
Diabetic cystopathy 8.5
Penile necrosis 8.4
Nephroangiosclerosis 8.4
chronic glomerulonephritis 8.3
glomerulosclerosis 8.3
Diabetic complications 8.2
Mesangioproliferative glomerulonephritis 8.2
IDDM10 8.1
Proliferative retinopathy 8.0
Diabetic microangiopathy 8.0
Uremic pericarditis 7.9
congenital hyperbilirubinemia 7.8
renal disease 7.8
Sickle cell nephropathy 7.7
Henoch-Schoenlein nephritis 7.7
glomerulopathy 7.7
Choledochoduodenal fistula 7.6
Glomerular diseases 7.6
proteinuria 7.6
diabetic angiopathy 7.6
CDFI 7.5
Proteinuria 7.5
Renal fibrosis 7.4
renal rickets 7.4
gouty nephropathy 7.4
IDDM8 7.4
Renal interstitial fibrosis 7.4
background retinopathy 7.3
diabetic hyperglycemia 7.3
Maculopathy 7.2
Myeloma cast nephropathy 7.2
hyporeninemic hypoaldosteronism 7.2
retinopathy 7.2
renin-dependent hypertension 7.1
Reflux nephropathy 7.0
Renal anemia 7.0
Diabetic maculopathy 7.0
HIVAN 7.0
membranous nephropathy 7.0
IDDM12 6.9
Adynamic bone disease 6.9
diabetic retinopathy 6.9
Bright's disease 6.9
IgA nephropathy 6.9
Focal segmental glomerulosclerosis 6.8
Chronic interstitial nephritis 6.8
hyperglycemia 6.7
Staphylococcus epidermidis infection 6.7
type 1 diabetes 6.7
Orbital apex syndrome 6.7
Gustatory sweating 6.7
Diabetic polyneuropathy 6.6
vitamin B12 deficiency anemia 6.6
NPHS2 6.6
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Symptom
excessive urination 7.5
KIDNEY 7.5
polyuria 4.9
ketonuria 4.4
acid regurgitation 4.1
abdominal fullness 3.8
asterixis 3.8
pedal edema 3.8
hypoproteinemia 3.7
disturbed balance 3.7
oliguria 3.5
Decreased activity 3.5
polydipsia 3.4
non-productive cough 3.4
lassitude 3.4
Gastrointestinal symptoms 3.3
urinary frequency 2.4
mental fatigue 2.3
limb pain 2.1
chorea 2.1
renal colic 1.9
dysuria 1.8
cough 1.8
consciousness disturbance 1.8
angina 1.8
alexithymia 1.8
shortness of breath 1.8
hip pain 1.7
muscle cramps 1.7
overweight 1.6
fever of unknown origin 1.5
hypersomnia 1.5
productive cough 1.4
decreased appetite 1.3
bradykinesia 1.3
night sweats 1.3
numbness 1.2
tonic-clonic seizure 1.2
cachexia 1.1
thinning 0.9
bloating 0.8
respiratory distress 0.7
dysarthria 0.6
dizziness 0.6
chronic cough 0.5
heartburn 0.5
chills 0.5
myalgia 0.4
flank pain 0.4
anorexia 0.4
vertigo 0.3
spasm 0.3
pallor 0.2
dyspnea 0.2
hyperoxia 0.2
shoulder pain 0.1
Ill 0.1
collapse 0.0
snoring 0.0
hepatomegaly 0.0
paresis 0.0
nausea 0.0
HSA -0.0
back pain -0.0
exertional dyspnea -0.2
exhaustion -0.2
epigastric pain -0.2
abdominal pain -0.2
arthralgia -0.3
weakness -0.4
hemiplegia -0.4
apathy -0.5
hepatosplenomegaly -0.6
vomiting -0.6
paresthesia -0.8
constipation -0.8
hunger -0.9
lethargy -1.0
flushing -1.1
sleepiness -1.1
more...
Drug
Caprylic Acid 11.5
Ibrolipim 11.5
Dilazep dihydrochloride 9.9
Succinic Acid 9.9
Mudanpi 9.2
Imidapril hydrochloride 9.2
Pyridoxamine 9.0
Avapro 8.7
Monopril 8.7
Camostat mesilate 8.7
Lotrel 8.4
Amiloride hydrochloride 8.4
Gliquidone 8.4
Aliskiren 8.1
Benfotiamine 8.0
Aliskiren fumarate 7.9
Fosinopril sodium 7.8
Alacepril 7.8
Benazepril hydrochloride 7.4
Medalist 7.4
Ramipril 7.1
Nitecapone 7.1
Micardis 7.1
Omacor 7.0
Bindarit 7.0
Magnolia bark 7.0
Aminoguanidine 7.0
Epalrestat 6.9
Arachidonic Acid 6.9
Olmesartan 6.8
Muzolimine 6.7
Tallow 6.7
Olmesartan medoxomil 6.7
Losartan potassium 6.6
Beraprost sodium 6.5
Cinnamon oil 6.5
Januvia 6.2
Trandolapril 6.2
Ponalrestat 6.1
Norvasc 6.1
Liraglutide 6.1
Ozagrel 6.1
Insulin detemir 6.0
NOV 5.8
Azelnidipine 5.7
Valsartan 5.6
Nafamostat mesilate 5.5
Esculin 5.5
Angiotensin II 5.5
Rosiglitazone 5.4
Albumin 5.4
Tranilast 5.4
Tolvaptan 5.4
Orgaran 5.4
Captopril 5.3
Pegvisomant 5.1
PDGF B-chain 5.0
Vitamin B 5.0
NAG 5.0
Emodin 5.0
Malonaldehyde 4.9
Cilostazol 4.8
Torasemide 4.8
Sevelamer 4.8
Ergosterol 4.8
Emodin 4.7
Vorinostat 4.6
Pirfenidone 4.6
Nephron 4.6
Safflower 4.6
Celebrex 4.6
Lacidipine 4.5
metformin hydrochloride 4.5
Roflumilast 4.5
Roflumilast 4.5
Cilazapril 4.4
Febuxostat 4.4
IPD 4.3
Rebamipide 4.3
Myricetin 4.2
more...
Enzyme
serum carnosinase 9.1
carnosinase 8.7
meprin B 7.6
HK2 7.4
myo-inositol oxygenase 7.2
EC 2.4.2.26 7.1
5,10-methenyltetrahydrofolate synthetase 7.0
NSY 6.7
calpain 10 6.5
aldose reductase 6.4
carnosine synthetase 6.3
pantetheinase 6.3
ACE 6.3
aspartyl aminopeptidase 6.2
renin 6.0
dimethylarginine dimethylaminohydrolase 5.8
beta-D-fucosidase 5.5
FPS 5.4
3-hydroxy-3-methylglutaryl-CoA lyase 5.2
thrombin-activatable fibrinolysis inhibitor 5.1
NADPH oxidase 5.1
AMP-activated kinase 5.0
NADPH oxidase 5.0
neurolysin 5.0
prolyl-tRNA synthetase 4.8
angiotensin-converting enzyme 2 4.8
ketohexokinase 4.8
alanine aminopeptidase 4.8
meprin 4.7
proteinase-3 4.7
eEF2 kinase 4.6
chymase 4.6
nucleotide pyrophosphatase 4.6
AGT 4.5
GTP cyclohydrolase I 4.5
GLO 4.4
tissue kallikrein 4.4
aminopeptidase A 4.4
hepsin 4.3
hepsin 4.3
prostasin 4.3
AMPK 4.2
glycine N-methyltransferase 4.2
glycine amidinotransferase 4.2
AMP-activated protein kinase 4.2
methylenetetrahydrofolate reductase 4.2
methylenetetrahydrofolate reductase 4.2
Thy1 4.1
ECH 4.1
chondroitin ABC lyase 4.0
fructokinase 4.0
nicotinamide phosphoribosyltransferase 4.0
GD3 synthase 4.0
kallikrein 3.9
poly(ADP-ribose) glycohydrolase 3.8
pregnancy-associated plasma protein-A 3.8
GSK 3.8
protein kinase C 3.8
sorbitol dehydrogenase 3.8
GM3 synthase 3.8
12-lipoxygenase 3.8
15-lipoxygenase 3.7
3-mercaptopyruvate sulfurtransferase 3.6
glucosylceramide synthase 3.6
DCF 3.6
superoxide dismutase 3.6
lysyl hydroxylase 3.6
prolidase 3.6
sphingosine kinase 3.6
O-GlcNAc transferase 3.6
matrix metalloproteinase 2 3.5
TACE 3.5
leucine aminopeptidase 3.4
isopeptidase 3.4
caspase-1 3.4
gamma-glutamylcysteine synthetase 3.4
3-hydroxy-3-methylglutaryl coenzyme A reductase 3.3
heme oxygenase 3.3
glutathione peroxidase 3.3
prolyl hydroxylase 3.3
more...
Compound
C20H18NO4 10.5
C8H12N2O2 10.5
SN 46 9.9
Sequoyitol 9.9
Skimmin 9.9
Dilazep dihydrochloride 9.9
C20H18NO4 9.9
Berberine iodide 9.5
Irbesartan 9.2
Pyridoxamine 9.0
Plantamajoside 8.2
Dihydrochalcone 8.2
1,5-isoquinolinediol 8.1
Taraxerol 8.1
Taraxerol 8.1
Calmagite 8.1
Diiodothyronine 7.9
DJP 7.9
4-hydroxyphenyl acetate 7.8
Lithospermic acid 7.8
Benazepril 7.7
Obacunone 7.7
C3H7NO2 7.7
STZ 7.6
Homocarnosine 7.5
Rhaponticin 7.4
Telmisartan 7.4
Isobavachalcone 7.4
Notoginsenoside R1 7.4
Spinasterol 7.3
Thiazolidinedione 7.2
EPA ethyl ester 7.2
Sennoside A 7.0
AGE 7.0
Cystine 7.0
Farrerol 6.9
TDGA 6.9
Moexipril 6.9
Rhein 6.8
Hordenine 6.8
4-aminobenzamide 6.7
pentosidine 6.7
Acetylshikonin 6.7
Pima 6.6
Berberine chloride 6.6
Losartan 6.6
Gentiopicroside 6.6
Anserine 6.5
Loganin 6.5
Polydatin 6.4
LPR 6.4
Paricalcitol 6.3
creatinine 6.3
Tangeretin 6.3
Fosinopril 6.3
12(S)-HETE 6.3
Zingerone 6.3
Calycosin 6.3
Carnosine 6.2
Dexpanthenol 6.2
NMOR 6.2
5-aminovalerate 6.1
Dibenzoylmethane 6.1
Tolrestat 6.1
Diosmin 6.0
Orientin 6.0
Angiotensin II 6.0
Sorbinil 6.0
Pioglitazone 6.0
Daphnetin 5.9
Fenofibrate 5.9
Danshensu 5.8
Berberine 5.8
Enalapril 5.8
Brazilin 5.8
8-OHdG 5.8
Scoparone 5.8
Candesartan cilexetil 5.7
Hippuran 5.7
Dimenhydrinate 5.7
more...