Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0011881 (diabetic nephropathy)
10,836 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein albumin 1787 insulin 1733 renin 797 collagen 716 Sep 627 fibronectin 524 Mol 476 angiotensin II 444 hemoglobin 324 chronic renal failure 280 ACE 275 cytokine 207 nephrin 206 superoxide dismutase 191 TNF 190 Ang II 180 angiotensin receptor 176 proximal tubule 175 GFR 172 angiotensin II receptor 166 STZ 154 TGF-beta 152 IL-6 147 transforming growth factor-beta 144 caspase-3 143 IDDM 137 vascular endothelial growth factor 137 catalase 131 tumor necrosis factor 128 NIDDM 128 connective tissue growth factor 127 serum albumin 119 mTOR 118 p38 117 calcium channel 113 ROS 108 MAPK 105 monocyte chemoattractant protein-1 104 SMA 101 endoplasmic reticulum 101 MCP-1 98 GSH 93 NRK 92 aldose reductase 92 angiotensinogen 89 ERK1 88 podocin 87 smooth muscle actin 84 PI3K 80 p65 79 Nrf2 79 plasminogen activator inhibitor-1 78 Smad3 77 Angiotensin-converting enzyme 77 Bcl-2 73 glutathione peroxidase 73 AT1 72 RAGE 71 E-cadherin 71 HDL 69 Albumin 69 interleukin-6 66 endothelial nitric oxide synthase 65 Pol 64 inducible nitric oxide synthase 64 N-acetyl-beta-D-glucosaminidase 64 cystatin C 62 adiponectin 62 erythropoietin 61 histone 60 TLR4 60 glucagon 59 SOD 58 C-reactive protein 58 ERK 57 peptidase 57 Smad2 57 ATP 57 catenin 57 AKT 56 more...

Disease diabetic nephropathy 10836 diabetes 5402 renal disease 3358 hypertension 1589 proteinuria 1575 type 2 diabetes 1441 microalbuminuria 1083 hyperglycemia 1056 renal failure 892 glomerulosclerosis 807 type 1 diabetes 721 chronic renal failure 616 retinopathy 484 cardiovascular disease 362 glomerulonephritis 350 diabetic retinopathy 346 obesity 276 atherosclerosis 226 heart failure 214 neuropathy 189 renal insufficiency 184 nephrotic syndrome 174 glomerulopathy 168 stroke 155 IgA nephropathy 151 chronic glomerulonephritis 149 myocardial infarction 149 hyperlipidemia 149 dyslipidemia 148 renal impairment 132 membranous nephropathy 132 lupus nephritis 128 cancer 128 essential hypertension 125 polycystic kidney 118 metabolic syndrome 115 nephrosclerosis 109 congestive heart failure 104 Proteinuria 102 anemia 95 GSH 93 uremia 88 vascular disease 88 ischemia 85 nephritis 84 coronary artery disease 84 diabetic neuropathy 82 tumor 76 coronary heart disease 74 myocardial ischemia 72 ATM 72 ventricular hypertrophy 72 hypoglycemia 71 glucose intolerance 70 hyperinsulinemia 64 acute renal failure 59 peripheral vascular disease 57 systemic lupus erythematosus 55 peripheral neuropathy 54 pyelonephritis 53 autonomic neuropathy 51 Evans 51 blindness 51 renal cell carcinoma 48 hypertensive nephropathy 48 kidney hypertrophy 47 interstitial nephritis 47 sepsis 47 amyloidosis 44 SEM 44 preeclampsia 43 vasculitis 42 chronic renal insufficiency 42 sepsis 42 hypercholesterolemia 40 Chronic kidney disease (CKD) 40 cardiomyopathy 37 WT1 35 metabolic disorder 34 arteriosclerosis 32 more...

Symptom polyuria 32 pain 31 cough 29 overweight 27 angina 25 anesthesia 15 dyspnea 11 respiratory distress 11 weakness 10 collapse 10 abdominal pain 9 polydipsia 8 fatigue 8 nausea 8 vomiting 7 oliguria 7 thinning 7 diarrhea 6 anorexia 6 shortness of breath 6 headache 5 hypoproteinemia 5 dizziness 5 exhaustion 4 Ill 4 back pain 4 seizures 4 cachexia 4 ketonuria 4 numbness 4 dysuria 3 vertigo 3 discomfort 3 discomfort 3 chorea 3 spasm 3 myalgia 3 starvation 3 dysarthria 2 paresis 2 alexithymia 2 sleepiness 2 abdominal fullness 2 fever of unknown origin 2 bradykinesia 2 analgesia 2 arthralgia 2 erythema 2 hyperoxia 2 tremor 2 chills 2 urinary frequency 2 hypothermia 2 Gastrointestinal symptoms 2 Decreased activity 2 hip pain 2 constipation 2 hepatomegaly 2 dystonia 1 consciousness disturbance 1 paresthesia 1 syncope 1 tinnitus 1 mental fatigue 1 disturbed balance 1 flank pain 1 tonic-clonic seizure 1 flushing 1 productive cough 1 nausea and vomiting 1 hypersomnia 1 insomnia 1 HSA 1 ataxia 1 shoulder pain 1 limb pain 1 pedal edema 1 chest pain 1 apathy 1 KIDNEY 1 more...

Drug Dial 158 ROS 108 lysine 101 Nephron 98 Nephron 98 Angiotensin II 78 Cardiovasc 74 Albumin 71 Monit 34 Captopril 30 vitamin E 29 Aliskiren 25 NAG 24 ROC 22 ADM 20 Ramipril 20 Aminoguanidine 18 Vitamin B 14 PTH 14 Pyridoxamine 13 Glucagon 13 Rosiglitazone 12 ascorbate 12 NADH 12 Indomethacin 11 MAP 10 Liraglutide 10 Nitric Oxide 10 DM1 10 Dermatol 8 Olmesartan 8 Valsartan 8 CCL 8 Leaf 7 ETA 7 Parkin 7 Vitamin E 7 Gel 7 Parkin 7 Growth hormone 6 BH4 6 Gelatin 5 Emodin 5 Growth hormone 5 Vitamin A 5 IL-2 5 Emodin 5 niacin 5 IFN-gamma 5 uPA 5 Serum albumin 4 ABC 4 Camostat mesilate 4 Cilostazol 4 NOV 4 EPA 4 Simvastatin 4 Glutathione 4 Adriamycin 4 TAK 4 Ginseng 4 Forskolin 4 Ouabain 3 Gliquidone 3 Troglitazone 3 Pravastatin 3 Vorinostat 3 Benfotiamine 3 Trandolapril 3 Photofrin 3 nitroglycerin 3 Heme 3 EPI 3 Tranilast 3 Ergosterol 3 PTC 3 CSF 3 TAT 3 Glycyrrhiza 3 Rutin 3 more...

Enzyme renin 797 ACE 477 mitogen-activated protein kinase 292 superoxide dismutase 239 protein kinase C 232 catalase 153 protein kinase 136 NADPH oxidase 131 caspase-3 111 NADPH oxidase 110 luciferase 106 ERK 99 aldose reductase 93 AMP-activated protein kinase 81 glutathione peroxidase 73 focal adhesion kinase 63 AMPK 41 ATPase 41 AMPK 40 HK2 32 GSK 32 kallikrein 30 plasmin 28 calcineurin 28 peroxidase 27 lactate dehydrogenase 27 alkaline phosphatase 26 alanine aminotransferase 24 NO synthase 24 MEK 24 collagenase 23 phosphatidylinositol 3-kinase 23 caspase-1 22 thrombin 21 PARP 21 proteasome 19 aspartate aminotransferase 19 reverse transcriptase 18 trypsin 18 carnosinase 18 phosphodiesterase 15 APC 15 NQO1 15 xanthine oxidase 14 heme oxygenase 14 urokinase-type plasminogen activator 14 methylenetetrahydrofolate reductase 13 CD10 13 methylenetetrahydrofolate reductase 13 RNase 13 caspase-9 12 cdc2 12 RNase 12 tissue plasminogen activator 12 serum carnosinase 11 cathepsin B 11 chymase 11 complex I 11 glutathione S-transferase 11 lipoprotein lipase 10 thromboplastin 10 angiotensin-converting enzyme 2 10 AST 10 MAP 10 guanylate cyclase 10 NOS 10 lysozyme 9 tissue kallikrein 9 CD13 9 matrix metalloproteinase 2 9 gamma-glutamyl transpeptidase 9 DCF 8 MMP 8 glutathione reductase 8 PKG 8 phospholipase A2 7 phosphoinositide 3-kinase 7 phospholipase C 7 alanine aminopeptidase 7 Thy1 7 more...

Compound glucose 2869 creatinine 1599 Clin 994 Dec 691 oxygen 559 urea 429 sodium 385 nitrogen 330 acetate 317 aldosterone 301 DNA 278 calcium 262 STZ 258 water 219 nitric oxide 206 Angiotensin II 193 TNF 190 Dial 158 Insulin 125 salt 110 lysine 106 phosphate 104 potassium 98 GSH 95 GSH 95 Ang II 85 galactose 78 sulfate 71 EDTA 70 EDTA 70 arginine 65 vitamin D 63 nicotinamide 62 8-OHdG 61 Diabetol 58 Diabetol 57 ATP 57 MDA 54 Irbesartan 53 iron 52 hydrogen 51 Losartan 48 cysteine 47 Cardiol 47 NADPH 46 NADPH 46 MTT 43 tyrosine 43 AGE 43 ASA 42 N-acetylcysteine 42 serine 42 His 40 NAD 40 alloxan 40 Pac 39 PAS 38 zinc 38 DPP 37 Collagen 35 NAD 33 Pima 31 phosphorus 30 Telmisartan 29 Cystine 29 homocysteine 29 Sodium 29 threonine 28 DBA 28 DBA 28 DBA 28 leucine 28 AMP 27 Resveratrol 27 cAMP 26 CAT 25 CAT 25 prostacyclin 25 CAT 25 alanine 24 more...

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