Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011881 (
diabetic nephropathy
)
10,836
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
albumin
1787
insulin
1733
renin
797
collagen
716
Sep
627
fibronectin
524
Mol
476
angiotensin II
444
hemoglobin
324
chronic renal failure
280
ACE
275
cytokine
207
nephrin
206
superoxide dismutase
191
TNF
190
Ang II
180
angiotensin receptor
176
proximal tubule
175
GFR
172
angiotensin II receptor
166
STZ
154
TGF-beta
152
IL-6
147
transforming growth factor-beta
144
caspase-3
143
IDDM
137
vascular endothelial growth factor
137
catalase
131
NIDDM
128
tumor necrosis factor
128
connective tissue growth factor
127
serum albumin
119
mTOR
118
p38
117
calcium channel
113
ROS
108
MAPK
105
monocyte chemoattractant protein-1
104
SMA
101
endoplasmic reticulum
101
more...
Disease
diabetic nephropathy
10836
diabetes
5402
renal disease
3358
hypertension
1589
proteinuria
1575
type 2 diabetes
1441
microalbuminuria
1083
hyperglycemia
1056
renal failure
892
glomerulosclerosis
807
type 1 diabetes
721
chronic renal failure
616
retinopathy
484
cardiovascular disease
362
glomerulonephritis
350
diabetic retinopathy
346
obesity
276
atherosclerosis
226
heart failure
214
neuropathy
189
renal insufficiency
184
nephrotic syndrome
174
glomerulopathy
168
stroke
155
IgA nephropathy
151
hyperlipidemia
149
myocardial infarction
149
chronic glomerulonephritis
149
dyslipidemia
148
membranous nephropathy
132
renal impairment
132
lupus nephritis
128
cancer
128
essential hypertension
125
polycystic kidney
118
metabolic syndrome
115
nephrosclerosis
109
congestive heart failure
104
Proteinuria
102
anemia
95
more...
Symptom
polyuria
32
pain
31
cough
29
overweight
27
angina
25
anesthesia
15
dyspnea
11
respiratory distress
11
weakness
10
collapse
10
abdominal pain
9
fatigue
8
polydipsia
8
nausea
8
oliguria
7
thinning
7
vomiting
7
anorexia
6
diarrhea
6
shortness of breath
6
dizziness
5
hypoproteinemia
5
headache
5
numbness
4
ketonuria
4
exhaustion
4
seizures
4
cachexia
4
Ill
4
back pain
4
discomfort
3
myalgia
3
discomfort
3
chorea
3
dysuria
3
vertigo
3
spasm
3
starvation
3
paresis
2
alexithymia
2
more...
Drug
Dial
158
ROS
108
lysine
101
Nephron
98
Nephron
98
Angiotensin II
78
Cardiovasc
74
Albumin
71
Monit
34
Captopril
30
vitamin E
29
Aliskiren
25
NAG
24
ROC
22
Ramipril
20
ADM
20
Aminoguanidine
18
Vitamin B
14
PTH
14
Pyridoxamine
13
Glucagon
13
NADH
12
Rosiglitazone
12
ascorbate
12
Indomethacin
11
Nitric Oxide
10
MAP
10
Liraglutide
10
DM1
10
Dermatol
8
CCL
8
Olmesartan
8
Valsartan
8
Gel
7
Parkin
7
Leaf
7
ETA
7
Parkin
7
Vitamin E
7
Growth hormone
6
more...
Enzyme
renin
797
ACE
477
mitogen-activated protein kinase
292
superoxide dismutase
239
protein kinase C
232
catalase
153
protein kinase
136
NADPH oxidase
131
caspase-3
111
NADPH oxidase
110
luciferase
106
ERK
99
aldose reductase
93
AMP-activated protein kinase
81
glutathione peroxidase
73
focal adhesion kinase
63
AMPK
41
ATPase
41
AMPK
40
GSK
32
HK2
32
kallikrein
30
plasmin
28
calcineurin
28
peroxidase
27
lactate dehydrogenase
27
alkaline phosphatase
26
MEK
24
alanine aminotransferase
24
NO synthase
24
collagenase
23
phosphatidylinositol 3-kinase
23
caspase-1
22
PARP
21
thrombin
21
aspartate aminotransferase
19
proteasome
19
trypsin
18
carnosinase
18
reverse transcriptase
18
more...
Compound
glucose
2869
creatinine
1599
Clin
994
Dec
691
oxygen
559
urea
429
sodium
385
nitrogen
330
acetate
317
aldosterone
301
DNA
278
calcium
262
STZ
258
water
219
nitric oxide
206
Angiotensin II
193
TNF
190
Dial
158
Insulin
125
salt
110
lysine
106
phosphate
104
potassium
98
GSH
95
GSH
95
Ang II
85
galactose
78
sulfate
71
EDTA
70
EDTA
70
arginine
65
vitamin D
63
nicotinamide
62
8-OHdG
61
Diabetol
58
ATP
57
Diabetol
57
MDA
54
Irbesartan
53
iron
52
more...