Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011881 (diabetic nephropathy)
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Human Gene/Protein
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase 11.5
OR2L8 11.5
PP13439 11.5
FLJ00279 11.5
ANKRD56 11.5
SET domain-containing protein 6 11.5
CTNNBIP1 protein 11.5
Eukaryotic translation initiation factor 4A, isoform 2 11.5
carnosinase 1 10.9
bone morphogenic protein type II receptor 10.5
LGP1 10.5
OR2AK2 10.5
MIOX protein 10.5
SFRS15 10.5
Engulfment and cell motility protein 1 10.5
CNDP1 10.4
ZNF236 10.2
UbA52 10.2
FRMD3 10.1
engulfment and cell motility 1 10.0
more...
Disease
Adult Fanconi syndrome 11.5
Chronic proliferative glomerulonephritis 11.5
nephropathy; hereditary 11.5
Hypercholesterolemia aggravated 11.5
Nodular diabetic glomerulosclerosis 11.5
diabetic nephropathy 11.5
Renal failure and impairment 11.5
Clinical diabetic nephropathy 10.9
Incipient diabetic nephropathy 10.9
Nodular glomerulosclerosis 10.4
GFND 9.9
Acute on chronic renal failure 9.9
Residual proteinuria 9.9
microalbuminuria 9.6
Microproteinuria 9.5
kidney hypertrophy 9.4
Segmental glomerulosclerosis 9.2
Hepatic calcification 9.2
von Willebrand disease type 2A 8.9
von Willebrand disease type 2A 8.9
more...
Symptom
excessive urination 7.5
KIDNEY 7.5
polyuria 4.9
ketonuria 4.4
acid regurgitation 4.1
abdominal fullness 3.8
asterixis 3.8
pedal edema 3.8
hypoproteinemia 3.7
disturbed balance 3.7
oliguria 3.5
Decreased activity 3.5
polydipsia 3.4
non-productive cough 3.4
lassitude 3.4
Gastrointestinal symptoms 3.3
urinary frequency 2.4
mental fatigue 2.3
limb pain 2.1
chorea 2.1
more...
Drug
Caprylic Acid 11.5
Ibrolipim 11.5
Succinic Acid 9.9
Dilazep dihydrochloride 9.9
Imidapril hydrochloride 9.2
Mudanpi 9.2
Pyridoxamine 9.0
Camostat mesilate 8.7
Monopril 8.7
Avapro 8.7
Lotrel 8.4
Gliquidone 8.4
Amiloride hydrochloride 8.4
Aliskiren 8.1
Benfotiamine 8.0
Aliskiren fumarate 7.9
Fosinopril sodium 7.8
Alacepril 7.8
Benazepril hydrochloride 7.4
Medalist 7.4
more...
Enzyme
serum carnosinase 9.1
carnosinase 8.7
meprin B 7.6
HK2 7.4
myo-inositol oxygenase 7.2
EC 2.4.2.26 7.1
5,10-methenyltetrahydrofolate synthetase 7.0
NSY 6.7
calpain 10 6.5
aldose reductase 6.4
carnosine synthetase 6.3
pantetheinase 6.3
ACE 6.3
aspartyl aminopeptidase 6.2
renin 6.0
dimethylarginine dimethylaminohydrolase 5.8
beta-D-fucosidase 5.5
FPS 5.4
3-hydroxy-3-methylglutaryl-CoA lyase 5.2
thrombin-activatable fibrinolysis inhibitor 5.1
more...
Compound
C8H12N2O2 10.5
C20H18NO4 10.5
C20H18NO4 9.9
Skimmin 9.9
Sequoyitol 9.9
SN 46 9.9
Dilazep dihydrochloride 9.9
Berberine iodide 9.5
Irbesartan 9.2
Pyridoxamine 9.0
Dihydrochalcone 8.2
Plantamajoside 8.2
Calmagite 8.1
Taraxerol 8.1
1,5-isoquinolinediol 8.1
Taraxerol 8.1
Diiodothyronine 7.9
DJP 7.9
4-hydroxyphenyl acetate 7.8
Lithospermic acid 7.8
more...