Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011860 (type 2 diabetes)
 57,723 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The purpose of this study was to investigate benzocyclobutene (BCB) derivatives as non-toxic curing agents to replace accelerated sulfur systems in certain synthetic biomedical materials. Prototype artificial spinal discs have been made and implanted in a few patients from a carbon black-filled copolymer of 1-hexene and 5-methyl-1,4-hexadiene (MHD), which is sulfur cured. The polymers investigated in this study were composed of 1-hexene, allyl-BCB, and MHD (or 7-methyl-1,6-octadiene, MOD). Curing was effected through reactions on BCB, forming carbon-carbon crosslinks. Preliminary cytotoxicity tests showed the material to be non-toxic, and the physical and mechanical properties of the BCB-cured materials were comparable with those of the sulfur-cured polymers.
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PMID:A new, non-toxic, curing agent for synthetic polyolefins. 147 11