Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011860 (type 2 diabetes)
 57,723 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two experimental inhomogeneous microfilled composites with spherical prepolymerized particles and an interpenetrating network (IPN), which provides a stable bond between prepolymerized spheres and the matrix (B-21 and B-51), and amalgam were used for Class II MOD fillings in mandibular molars. After 3 and 6 months of clinical use, wear of the material was measured with a replica technique and a modified surface roughness test. The failure mode was analysed with SEM photographs also using a replica technique. After 6 months the wear of the composites in the occlusal contact area was more than twice as high as the substance loss of amalgam. It was concluded that the composites were not suitable for fillings bearing occlusal load. However, the failure mode seen in the SEM for B-21 indicated that the IPM leads to a stable incorporation of the spherical prepolymerized particles into the matrix. Due to its good surface characteristics B-21 should be further investigated for its use as an anterior composite. B-51 was especially designed as a posterior composite. Beside the construction elements of B-21 it contained also barium glass spheres to obtain radiopacity. This hybrid construction failed due its wear mode.
 ...
PMID:In vivo evaluation of occlusal wear of two experimental composites versus amalgam. 659 75

A 49-year-old woman with poorly controlled type 2 diabetes mellitus was admitted to hospital complaining of fever, vomiting, and lower abdominal pain. Laboratory investigation revealed leukocytopenia, high blood sugar, and pyuria. Pyelonephritis was then diagnosed. Escherichia coli was isolated from blood and urinary cultures. In spite of antimicrobial therapy, the patient's condition deteriorated. A computed tomography scan of the abdomen on the second day of hospitalization revealed the presence of air in the collecting system of the left kidney. Emphysematous pyelonephritis was diagnosed, and a renoureteral catheter was promptly inserted via the left ureter into the affected pelvis of the left kidney. Imipenem, cefotiam, and levofloxacin were administered during the clinical course. This early intervention and the appropriate antimicrobial therapy were effective in resolving the infection. Urinary tract infections should be carefully managed in patients with poorly controlled diabetes mellitus.
 ...
PMID:Emphysematous pyelonephritis successfully treated by early intervention using a renoureteral catheter. 1955 6