Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011860 (type 2 diabetes)
 57,723 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Three different indirect adhesive inlay systems were investigated for marginal fit and microleakage. MOD cavities were prepared in 67 extracted sound premolar teeth initially with parallel cavity walls. Thirty-four of the premolars had the cavity walls modified to a 10 degrees and 33 to a 15 degrees occlusal divergence. EOS, Isosit and Hi-Ceram porcelain inlays did not fit cavities prepared with parallel walls. All inlays in the Isosit and porcelain groups were able to be seated without modifications in cavities prepared with either a 10 degrees or 15 degrees occlusal divergence. Inlays made by the EOS system required considerable modification of the fitting surface in order for them to fit. Results showed the EOS system to have the largest marginal gaps before cementation (P < 0.001). There was no significant difference in leakage between the three inlay systems after cementation (P < 0.05). The cementum margins leaked more than margins finished on enamel for all inlay systems (P < 0.05). It is concluded from this study that inlay cavities for Isosit and porcelain require at least a 10 degrees occlusal divergence of cavity walls to permit the fitting of inlays without unacceptable modification. The EOS inlays required considerable trimming even when a 15 degrees occlusal divergence of the cavity walls was used.
 ...
PMID:Marginal fit and microleakage of indirect inlay systems. 839 88

The purpose of this in vitro study was to evaluate the microleakage of direct and indirect inlay/onlay systems. Two of the groups investigated have indirect applications only and consist of microfine composites. The other two groups of inlay/onlay systems have both direct and indirect applications and are hybrid composites. Standardized MOD preparations were cut in 60 extracted human premolars. One gingival margin was placed in enamel above the cementoenamel junction (CEJ) and the other was placed in dentine below the CEJ. The inlays were made and luted according to each manufacturer's recommendation. The restored teeth were thermocycled and immersed in a basic fuchsin solution for 24 h. Following the mesiodistal sectioning of the specimens, extent of dye penetration at the restoration-glass ionomer cement and tooth-glass ionomer cement interfaces were scored using a stereomicroscope. Both direct and indirect inlays showed substantial leakage at gingival-dentine margins. However, there was only superficial leakage at enamel margins. Comparing the overall indirect inlay systems, EOS inlay leaked the most (P < 0.05). Indirect Brilliant Dentin inlays showed a significantly smaller amount of leakage than the other inlay systems. SR-Isosit and Estilux Posterior C VS inlays provided a favourable marginal seal. In the case of Brilliant Dentin and Estilux Posterior C VS, indirect inlays leaked more than direct inlays. Generally, no significant difference was observed between the interfaces evaluated in microleakage performance.
 ...
PMID:Microleakage of direct and indirect inlay/onlay systems. 885 Jan 64