Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011860 (
type 2 diabetes
)
57,723
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The results of 8 years of combined caries prophylaxis (fluoride tablets in school, brushing with aminofluoride gel, motivation of teachers, pupils and parents) are reported from the community of Massagno TI.
Caries
reduction of about 60%, or from 2.72 new lesion to 1.12 new lesion per pupil and year. About 60% of pupils did not require dental treatment in the year 1977/78. Root canal treatment and fillings of anterior teeth have all but disappeared. MO and
MOD
fillings have receded more than occlusal fillings. The community and the canton have economized some SFr. 20000.-per annum.
...
PMID:[Prevention in the schools of Massagno, Ticino: results after 8 years]. 29 28
The purpose of this study was to examine the microleakage and cusp fracture resistance of heat-treated composite resin inlays. One hundred and twenty extracted human bicuspid teeth were prepared with
MOD
Class II preparations and divided into 12 experimental groups. Ten extracted human teeth were kept sound as positive controls and 10 of the prepared teeth were left unrestored as negative controls for the cusp fracture resistance experiment. The remaining prepared teeth were grouped and restored with the following restorations: bulk or incremental placement, light-cured inlays, heat-treated inlays "cemented" with enamel bonding agent, enamel bonding agent/glass ionomer "sandwich", or a dentinal bonding agent. Heat-treated inlays showed significantly (P less than 0.05) less microleakage than all other groups. The cusp fracture resistance of the heat-treated inlays was in the same magnitude as that of the traditionally placed composite resin restoration. All restorations were significantly (P less than 0.05) lower in cusp fracture resistance than sound non-
carious teeth
.
...
PMID:Microleakage and cusp fracture resistance of heat-treated composite resin inlays. 200 91
The purpose of this study was to investigate the reasons for placement and replacement of restorations provided to military personnel by all 34 dentists stationed in the four Atlantic provinces of Canada. All dentists who participated in this study are salaried. Over a period of 30 working days, each dentist recorded information on all restorations performed. Data were collected on dentists' year of graduation, patient age, treatment requirements, tooth number, restoration class, materials used and reasons for placement and replacement. All dentists used the same data collection form which was pilot tested. Information was collected on 2,280 restorations from 643 adults, 18 to 57 years of age. Of all restorations, 54.3% were placements and 45.7% were replacements. No difference in placement and replacement rates between amalgam and composites was reported. The major reason for placement was primary caries (90%). The major reasons for replacements were recurrent caries (40.0%), primary caries of interproximal surfaces (18.9%), and fractured restorations (12.3%). Of the 297
MOD
restorations, 74.3% were replacements and of the 1,140 Class I + III + V restorations, 27.8% were replacements. This study showed that about half of the restorative work carried out were replacements.
Caries
is the primary reason for placement and replacement of restorations in adults.
...
PMID:Placement and replacement of restorations in a military population. 187 40
One hundred and twenty caries-free molar teeth were stored in saline. Three types of cavities were prepared in these teeth: conventional
MOD
, parallel-sided
MOD
with no buccal or lingual extensions, and a slit cavity.
Cavity
dimensions were recorded. Each group of teeth were restored with either a microfine or conventional composite, used in conjunction with a dentine adhesive. Cusp movement was recorded via two linear variable displacement transducers attached to the cusps. Using dye penetration studies, the marginal adaptation of the material to the teeth was assessed. In a small number of cases, the amount and type of cuspal movement and the degree of dye penetration was variable, depending on cavity design and the composite used, but generally cusp movement was unaffected by variation in cavity outline.
...
PMID:Cusp movement of molar teeth with composite filling materials in conventional and modified MOD cavities. 252 8
This study compared the diagnostic efficacy of four imaging modalities for the detection of artificially induced recurrent caries: intraoral film, direct digital bitewing images, tuned apertuce computed tomography (TACT) slices and iteratively restored TACT images using an in vitro model. Twenty-four posterior teeth were prepared for
MOD
inlay restorations. These were then restored with different restorative materials (amalgam, Herculite and Durafill). Lesions were simulated in half the number of surfaces studied. These lesions were created either at the intersection of the facial or lingual walls and the gingival floor or on the gingival floor midway between the facial and lingual walls in the proximal boxes of the
MOD
restorations. Analysis of observations from 8 observers using ROC curve reveal the superior diagnostic efficacy with TACT iteratively restored images (Az for TACT iteratively restored images = 0.9171, TACT slices = 0.7052, Film = 0.6608, direct digital images = 0.5979). ANOVA revealed significance with respect to the imaging modality used (p < 0.0001). The results suggest that TACT images hold promise as a more effective imaging modality than film or direct digital systems for detection of recurrent caries.
Caries
Res 1998
PMID:Tuned aperture computed tomography and detection of recurrent caries. 943 68
Evidence is increasing that oral health has important impacts on systemic health. This paper presents data from the third National Health and Nutrition Examination Survey (NHANES III) describing the prevalence of
dental caries
and periodontal diseases in the older adult population. It then evaluates published reports and presents data from clinical and epidemiologic studies on relationships among oral health status, chronic oral infections (of which caries and periodontitis predominate), and certain systemic diseases, specifically focusing on
type 2 diabetes
and aspiration pneumonia. Both of these diseases increase in occurrence and impact in older age groups. The NHANES III data demonstrate that
dental caries
and periodontal diseases occur with substantial frequency and represent a burden of unmet treatment need in older adults. Our review found clinical and epidemiologic evidence to support considering periodontal infection a risk factor for poor glycemic control in
type 2 diabetes
; however, there is limited representation of older adults in reports of this relationship. For aspiration pneumonia, several lines of evidence support oral health status as an important etiologic factor. Additional clinical studies designed specifically to evaluate the effects of treating periodontal infection on glycemic control and improving oral health status in reducing the risk of aspiration pneumonia are warranted. Although further establishing causal relationships among a set of increasingly more frequently demonstrated associations is indicated, there is evidence to support recommending oral care regimens in protocols for managing
type 2 diabetes
and preventing aspiration pneumonia.
...
PMID:Impact of oral diseases on systemic health in the elderly: diabetes mellitus and aspiration pneumonia. 1124 53
Packable resin composites may offer improved properties and clinical performance over conventional resin composites or dental amalgam. This in vitro study examined the cuspal stiffness of molars restored with a packable resin composite, a conventional posterior microfilled resin composite and amalgam. Forty-eight intact caries-free human third molars were distributed into four treatment groups (n=12) so that the mean cross-sectional areas of all groups were equal. Standardized
MOD
cavity preparations were made and specimens restored using one of four restorative materials: (1) a spherical particle amalgam (Tytin); (2) Tytin amalgam with a dentin adhesive liner (OptiBond Solo); (3) a conventional microfilled posterior resin composite (Heliomolar); (4) a packable posterior resin composite (Prodigy Posterior). Cuspal stiffness was measured using a Bionix 200 biomaterials testing machine (MTS). Specimens were loaded vertically to 300 N at a crosshead speed of 1.0 mm/minute. Stiffness was measured at 10 intervals: (1) prior to cavity preparation (intact); (2) following cavity preparation, but before restoration; (3) seven days after restoration; then (4) 1, 2, 3, 4, 5, 6 and 12 months after restoration. All specimens were stored at 37 degrees C in deionized water throughout the study and thermocycled (5 degrees/55 degrees C; 2000 cycles) monthly for 12 months. Repeated Measures ANOVA revealed significant differences among treatment groups over time (p<0.0001).
Cavity
preparation reduced cuspal stiffness by more than 60%. At 12 months, the cuspal stiffness of restored teeth was, on average, 58% that of intact specimens. Neither the packable nor the conventional resin composite increased cuspal stiffness over that of amalgam.
...
PMID:The influence of a packable resin composite, conventional resin composite and amalgam on molar cuspal stiffness. 1221 72
The purpose of this paper is to provide guidelines to assist in the selection of dental materials for restoring posterior teeth in adolescents. Currently, amalgam is still the best plastic restorative material for some Class I cavities, and for Class II cavities and all multi-surface restorations. Tooth-coloured materials are preferred by some patients and dentists, however these alternatives are more technique sensitive than amalgam. Composite resin is the most common direct placement alternative to dental amalgam, providing patients with relatively low cost, tooth-coloured restorations. However, composite resins have limited indication, their placement is more time-consuming than for amalgam, cost-benefit considerations are a concern, difficulty in obtaining a marginal seal persists and there are few long-term studies published in the peer reviewed scientific literature. The literature currently supports the use of composite resin for the restoration of a limited range of Class I and Class II cavities. Composite resin restorations are not recommended for
MOD
or other multi-surface restorations. In selected clinical situations, fissure sealants, preventive resin restorations and glass ionomer cement are also appropriate materials to use to restore posterior teeth. Fissure sealants, when properly maintained, can play a significant role in the prevention and control of
dental caries
in pits and fissures in primary and permanent teeth. Preventive resin restorations should be placed to restore deep pits and fissures with incipient caries and/or developmental defects in primary and permanent teeth. Glass ionomer cement may be used for restoring Class V cavities where appearance is not the primary concern, for conservative Class III cavities, and as a provisional restorative material. It is not recommended for Class II or IV restorations.
...
PMID:Direct placement restorative materials for use in posterior teeth: the current options. 1533 60
Diabetes mellitus, is a common chronic disease, and its prevalence in the United States, particularly
type 2 diabetes
, is increasing. Complications associated with diabetes impose a heavy burden on many people, especially among certain minority populations. Periodontal diseases,
dental caries
, and tooth loss also are common conditions in the United States, but their prevalence is generally decreasing. Nevertheless, among important subgroups of the population, particularly certain minority and economically disadvantaged groups, there is a disproportionately higher burden of periodontal diseases,
dental caries
, and tooth loss. This article reviews the post-1960 English-language literature on the relationship between diabetes and oral health, specifically focusing on periodontal disease,
dental caries
, and tooth loss. Substantial evidence exists to support the role of diabetes and poorer glycemic control as important risk factors for periodontal disease. Additionally, the evidence provides support for viewing the relationship between diabetes and periodontal diseases as bidirectional. However, additional research is necessary to firmly establish that treating periodontal infections can contribute to glycemic control management and possibly to the reduction of
type 2 diabetes
complications. The literature does not describe a consistent relationship between
type 2 diabetes
and
dental caries
. It reports increased, decreased, and similar caries experiences between those with and without diabetes. This review suggests that currently there is insufficient evidence to determine whether a relationship between diabetes and risk for coronal or root caries exists. Most of the reviewed studies reported greater tooth loss in people with diabetes. However, the differences were slight and not significant in several of the reports. Furthermore, this review of the association between diabetes and tooth loss reveals that valid population-based evidence generalizable to the US population is sparse. Further investigations of the association of diabetes with
dental caries
and tooth loss are warranted. If adverse effects of diabetes on
dental caries
and/or tooth loss are substantiated, the results of such studies would help design intervention studies to prevent or reduce the occurrence of
dental caries
and tooth loss in people with diabetes. These results also may affect existing clinical practice protocols and promote new public policy related to diabetes.
...
PMID:Diabetes, periodontal diseases, dental caries, and tooth loss: a review of the literature. 1564 24
Approximately 7% of pregnant women develop gestational diabetes mellitus (GDM), a usually transient form of diabetes mellitus, because of the production of some placental and maternal adipose tissue elaborated hormones that alter glucose metabolism. In most women the disorder resolves at delivery, but within 10 years 50% to 70% of these women go on to develop
type 2 diabetes
. The identification of women with past medical histories of GDM is a clinically useful marker for alerting the dentist to patients at heightened risk of occult
type 2 diabetes
, with a possible greater risk of developing periodontal disease and
dental caries
. Screening these patients for diabetes and establishing a preventative dental regimen may result in reducing the number of women with undiagnosed diabetes and diabetes-associated dental and cardiovascular diseases.
...
PMID:A past medical history of gestational diabetes: its medical significance and its dental implications. 1723 28
1
2
3
Next >>