Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011854 (type 1 diabetes)
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Human Gene/Protein
imogen 38 10.6
KIAA1838 10.6
BAT1 protein 10.6
CAPSL 10.6
FLJ11152 10.6
FLJ32798 10.6
C2orf79 10.6
VTCN1 protein 10.6
MRPS21 10.6
TTC34 10.6
IDDM1 10.6
TRBV6-3 10.6
bactericidal/permeability-increasing protein-like 1 10.6
Aryl hydrocarbon receptor nuclear translocator-like 10.6
CAG-isl 7 10.6
NUP50 protein 10.6
TRAJ53 10.6
TRBV6-2 10.6
ATPase family, AAA domain containing 1 10.6
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 10.6
Similar to cytokine 10.6
protein EFR3 homolog B 10.6
FLJ00279 10.6
IDD 10.6
DKFZp667F0711 10.6
C14orf181 10.6
IDDM 10.5
IDDM5 10.1
C6orf208 10.0
insulinoma-associated protein 2 9.7
C1q/TNF-related protein 8 9.6
F8A1 9.6
DCAL-1 9.6
IGLL3 9.6
HUMPPA 9.6
KIAA0215 9.6
transcription factor PAX4 9.6
TRAJ9 9.6
PCDHB16 9.6
HLA-DQ-beta 9.6
ZNF187 9.6
zinc transporter 8 9.6
glutamate decarboxylase GAD65 9.4
type 1 diabetes autoantigen 9.4
SUMO4 9.4
NIDD 9.3
IA-2 9.3
ICA12 9.3
islet-specific glucose-6-phosphatase catalytic subunit-related protein 9.2
C1QTNF6 9.2
interferon induced with helicase C domain 1 9.1
DQw3.2 9.1
Lipopolysaccharide-responsive and beige-like anchor protein 9.0
PTP-HSCF 9.0
HLA-DQB1/DRB1 9.0
TRBV4-3 9.0
EFHB 9.0
AI4 9.0
FYB protein 9.0
NKG2H 9.0
AngA 9.0
PLEKHN1 9.0
FAM63B 9.0
psoriasis susceptibility 1 candidate 1 9.0
C6orf120 9.0
UBASH3A 9.0
IGHV3-66 9.0
UHX1 9.0
LADA 9.0
paired box 4 8.8
Zinc transporter 8 8.8
C4B3 8.8
HLA DQB1 8.7
NIDDM 8.7
PPIL2 8.7
TRBV31 8.6
Sialic acid acetylesterase 8.6
DNASE1L1 8.6
WDR27 8.6
KLHL35 8.6
more...
Disease
Hypos 10.6
Drug-induced malabsorption 10.6
Tropical diabetes 10.6
stage IIB melanoma 10.6
type 1 diabetes 10.6
Other biliary tract disorders 10.6
IDDM15 10.6
IDDM18 10.6
IDDM10 10.6
IDD 10.5
IDDM5 10.4
IDDM8 10.3
IDDM12 10.2
IDDM2 10.1
IDDM7 10.1
IDDM17 10.0
IDDM4 9.9
IDDM13 9.8
Hypoglycemia unawareness 9.7
Congenital rubella infection 9.6
mumps pancreatitis 9.6
Latent autoimmune diabetes in adults 9.5
Mauriac syndrome 9.4
Diabetic mastopathy 9.3
Autoimmune Diabetes 9.3
IDDM6 9.2
IDDM11 9.0
Diabetes complicating pregnancy 9.0
Childhood atopic dermatitis 9.0
Hepatic glycogenosis 9.0
MRDM 9.0
Hypoglycemic encephalopathy 9.0
Diabetic diarrhea 9.0
Hypoglycemic episodes 8.8
Microproteinuria 8.6
Diabetic cheiroarthropathy 8.6
IDDM3 8.6
Insulin allergy 8.3
diabetic ketoacidosis 8.3
Endocrine pancreas 8.3
Endocrine pancreas 8.3
brittle diabetes 8.2
Clinical diabetic nephropathy 8.0
Starvation ketoacidosis 8.0
Type V hyperlipidemia 8.0
Proliferative retinopathy 7.9
Wolcott-Rallison syndrome 7.9
Bullosis diabeticorum 7.9
Demyelinating disorders 7.8
Diabetic polyneuropathy 7.8
Diabetic microangiopathy 7.8
Diabetic dermopathy 7.8
RP24 7.8
Autoimmune Addison's disease 7.7
Diabetic amyotrophy 7.7
MODY 7.6
Ramon syndrome 7.6
MODY2 7.6
Postpartum thyroiditis 7.5
NOD 7.5
Lipohypertrophy 7.5
PNDM 7.5
Macroangiopathy 7.5
Somogyi phenomenon 7.4
autoimmune endocrine disorder 7.4
Celiac crisis 7.4
Neonatal polycythemia 7.4
TNDM 7.4
GAD 7.4
microalbuminuria 7.4
other autoimmune disease 7.3
MODY3 7.3
Cardiac autonomic neuropathy 7.3
background retinopathy 7.3
Lipemia retinalis 7.3
Neonatal hypertension 7.3
Critical illness myopathy 7.3
Wolfram syndrome 7.3
autoimmune thyroid disease 7.2
Addison's disease 7.2
more...
Symptom
Burning mouth 7.3
feeling faint 7.0
Gastrointestinal discomfort 7.0
ketonuria 7.0
Tissue sensitivity 6.5
disturbance of sensation 6.4
feeling sick 5.7
polydipsia 5.4
polyuria 5.2
Cushingoid 5.2
Cushingoid 5.1
Foot pain 5.0
corpulence 4.3
frequent urination 4.2
dysosmia 4.1
hepatomegaly 3.5
muscle stiffness 3.3
physical exhaustion 3.2
jaw pain 3.1
Gastrointestinal symptoms 3.0
cerebellar ataxia 2.9
dry skin 2.9
bloating 2.9
overweight 2.8
disturbed balance 2.8
muscle rigidity 2.5
rigors 2.5
hyperemesis gravidarum 2.5
dark urine 2.4
lassitude 2.4
visual hallucination 2.4
chorea 2.4
hyperemesis 2.4
neurological disability 2.3
thirsty 2.3
enuresis 2.2
exhaustion 2.2
lethargy 2.2
forgetfulness 2.2
right upper quadrant pain 2.2
hypoproteinemia 2.0
leg pain 1.9
tachypnea 1.9
abdominal pain 1.8
abdominal discomfort 1.8
asthenia 1.8
incoordination 1.8
nausea 1.7
Neuropathic pain 1.7
vomiting 1.6
low back pain 1.6
emaciation 1.5
hyperesthesia 1.5
abdominal cramps 1.5
dysarthria 1.5
ataxic gait 1.5
retching 1.5
urinary frequency 1.4
hunger 1.4
excessive sweating 1.4
decreased appetite 1.4
halitosis 1.4
myalgia 1.4
nausea and vomiting 1.4
dental pain 1.4
Fluctuation 1.3
pallor 1.3
Depressive symptoms 1.2
leg edema 1.2
partial seizure 1.2
thinning 1.1
myoclonus 1.1
tense 1.1
weakness 1.1
groin pain 1.0
anosmia 1.0
discomfort 1.0
flushing 0.9
intestinal bleeding 0.9
dizziness 0.9
more...
Drug
Lycium bark 10.6
Brocal 9.6
Ocinaplon 9.0
Pramlintide 8.8
Medalist 8.7
Nemifitide ditriflutate 8.6
Abetimus sodium 8.6
Symlin 8.5
Insulin glulisine 8.3
Imidapril hydrochloride 8.3
Insulin aspart 8.2
Insulin glargine 8.2
Lantus 8.1
Insulin lispro 7.9
Mecasermin rinfabate 7.8
Visilizumab 7.8
Insulin detemir 7.7
Rubitecan 7.6
Amiloride hydrochloride 7.4
Humalog 7.4
BETA-2 7.3
DM1 7.0
Lisofylline 6.8
Prolastin 6.8
Exametazime 6.8
Roquinimex 6.7
Candoxatril 6.6
Humulin 6.5
Pleconaril 6.3
Ziprasidone hydrochloride 6.2
Metreleptin 6.2
Fampridine 5.8
Exenatide 5.7
Candoxatril 5.7
Diethylpropion 5.5
Palonosetron hydrochloride 5.5
Morphine hydrochloride 5.5
Lescol 5.5
Gliclazide 5.3
Lescol 5.2
Vatalanib 5.1
Colesevelam 4.9
Liraglutide 4.8
Genasense 4.8
Glucagon 4.7
Ontak 4.7
Ontak 4.7
Folic Acid 4.6
Ximelagatran 4.5
Alefacept 4.3
Methyldopa 4.3
CET 4.3
Beta-2 4.2
Darbepoetin alfa 4.2
Iodixanol 4.2
Anakinra 4.2
Sandostatin LAR 4.1
CPR 4.1
Muse 4.1
Belimumab 4.0
Ethylcellulose 4.0
Abatacept 4.0
Glybenclamide 4.0
Sandostatin 3.9
Sandostatin 3.9
Aminoguanidine 3.9
Resovist 3.8
Efalizumab 3.8
Efalizumab 3.7
Sodium alginate 3.7
Dexfenfluramine 3.6
PDL 3.5
Epoetin 3.5
IFN-gamma 3.5
Febuxostat 3.4
Ramipril 3.4
Prednisone 3.4
Human Serum Albumin 3.4
Trental 3.3
Fenbendazole 3.3
more...
Enzyme
formyl-CoA transferase 6.3
CSAD 5.9
glutamate decarboxylase 5.7
nardilysin 5.6
DIPP 5.6
calpain 10 5.6
GPI-PLD 5.3
thyroid peroxidase 5.2
inositol polyphosphate kinase 5.2
21-hydroxylase 5.0
deoxyhypusine synthase 4.9
glucokinase 4.8
transglutaminase 4.7
carboxypeptidase E 4.5
GLO 4.5
acetoacetyl-CoA reductase 4.4
dihydroxyacetone phosphate acyltransferase 4.2
retinyl ester hydrolase 4.2
aldose reductase 4.2
prolyl-tRNA synthetase 3.9
LMT 3.8
peptidylarginine deiminase 3.7
ACE 3.5
biliverdin reductase 3.5
hepsin 3.4
hepsin 3.4
granzyme B 3.4
dimethylarginine dimethylaminohydrolase 3.3
AGT 3.3
dipeptidyl peptidase IV 3.2
proteinase-3 3.2
kynurenine aminotransferase 3.1
glucose-6-phosphatase 3.1
cathepsin H 3.1
meprin 3.1
nicotinamide phosphoribosyltransferase 3.0
phosphoglyceromutase 3.0
methionine synthase reductase 2.9
angiotensin-converting enzyme 2 2.9
alpha-glucosidase 2.9
furin 2.9
paraoxonase 2.8
12-lipoxygenase 2.8
KAT 2.8
3-hydroxyacyl-CoA dehydrogenase 2.8
3-hydroxyacyl-CoA dehydrogenase 2.7
inositol 3-kinase 2.7
eEF2 kinase 2.7
3-mercaptopyruvate sulfurtransferase 2.7
indoleamine 2,3-dioxygenase 2.7
isoamylase 2.6
esterase D 2.6
lysyl hydroxylase 2.6
clostripain 2.6
renin 2.6
cathepsin S 2.6
thrombin-activatable fibrinolysis inhibitor 2.6
calcium pump 2.6
C3 convertase 2.6
paraoxonase 2.6
CYP27A1 2.5
acyl-CoA thioesterase 2.5
CPR 2.5
PRA 2.5
PHD 2.4
15-lipoxygenase 2.4
AMP-activated protein kinase 2.4
chondroitinase AC 2.3
NADPH oxidase 2.3
lipoprotein lipase 2.3
VOR 2.3
NADPH oxidase 2.3
PTPase 2.2
NO synthase 2.2
GCA 2.1
MIP 2.1
E-2 2.1
APC 2.1
alanine aminopeptidase 2.1
insulin-degrading enzyme 2.1
more...
Compound
BG 105 10.6
Catenarin 10.6
Ribonic acid 9.6
DG 2 7.8
Norval 7.6
2-hydrazinoquinoline 7.6
Previtamin D3 7.6
Navidrex 6.9
Fructosamine 6.8
AR 1 6.6
hexahydropyridazine 6.4
STZ 6.3
L-365260 6.3
Chlorpropamide 6.3
1,5-isoquinolinediol 6.1
Diethylpropion 6.1
IAA 6.0
BCM 5.9
M 14 5.8
IAA 5.8
Dithizone 5.7
Diabetol 5.6
Syringin 5.6
Insulin 5.6
Boswellic acid 5.5
Metanephrine 5.5
DQ1 5.5
1,5-AG 5.5
Diabetol 5.3
Thiazolidinedione 5.3
Aucubin 5.2
Magnesium hydroxide 5.2
5-aminovalerate 5.2
TKB 5.2
Homotaurine 5.1
Sulfatide 5.1
DPT 5.1
2-methyl-2-butanol 5.1
DAQ 5.0
Pantethine 5.0
DNC 4.9
DNC 4.9
2-methyl-2-butanol 4.9
Nandrolone decanoate 4.9
pentosidine 4.9
alloxan 4.9
25-Hydroxyvitamin D 4.8
FUR 4.8
TDT 4.8
Monastral Blue 4.8
NKT 4.7
Pima 4.7
Glucagon 4.7
B17 4.7
glucose 4.6
Sepiapterin 4.5
Fibrinopeptide A 4.5
Irbesartan 4.5
4-phenylbutanoic acid 4.5
Sorbinil 4.5
DMB 4.5
CONV 4.4
Tropisetron 4.4
Glimepiride 4.4
ITG 4.4
Fosinopril 4.4
Bilobalide 4.4
Naringin 4.3
238A 4.3
MHT 4.3
Butein 4.3
Metformin 4.3
Metformin 4.2
Vitamin D 4.2
Wellcome 4.2
Resiniferatoxin 4.2
GRG 4.1
DMB 4.1
DR-1 4.1
Propylparaben 4.1
more...