Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0011854 (type 1 diabetes)
20,749 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein insulin 8654 IDDM 2220 Sep 1225 HLA 1013 cytokine 843 hemoglobin 814 NOD 805 CD4 673 NIDDM 620 glucagon 618 Mol 602 albumin 539 glutamic acid decarboxylase 514 CD8 441 autoantigen 436 DR4 326 GAD65 325 IA-2 318 DR3 292 IL-10 287 gut 285 major histocompatibility complex 278 GAD 268 interferon 252 MHC 250 IDD 249 IFN 233 human leukocyte antigen 231 proinsulin 221 DQB1 220 IFN-gamma 217 HLA class II 208 TNF 207 CD25 202 IL-4 199 HLA-DR 197 She 191 thymus 189 IL-6 186 collagen 175 tumor necrosis factor 170 HDL 170 IL-2 155 DQ2 149 renin 144 MHC class II 142 growth hormone 139 lymphoid 139 TNF-alpha 138 TCR 138 DM1 130 chemokine 128 leptin 124 STZ 123 HLA-DQ 122 DRB1 121 tyrosine phosphatase 118 endoplasmic reticulum 117 IgA 117 Pol 116 HLA-DR3 116 interferon-gamma 112 DQA1 111 ATP 105 PTPN22 102 protein tyrosine phosphatase 101 Fas 99 caspase-3 96 somatostatin 96 CTLA-4 95 IL-1 93 inducible nitric oxide synthase 93 T cell receptor 93 IL-17 91 ACE 89 amylin 89 CTLA4 85 HLA-DRB1 84 HLA-DR4 83 Cytokine 82 more...

Disease type 1 diabetes 20749 diabetes 11648 type 2 diabetes 2930 hypoglycemia 1517 hyperglycemia 1503 autoimmune disease 1045 renal disease 918 NOD 805 diabetic nephropathy 721 hypertension 700 obesity 623 retinopathy 610 diabetic ketoacidosis 578 rheumatoid arthritis 523 multiple sclerosis 493 microalbuminuria 429 cardiovascular disease 399 celiac disease 394 systemic lupus erythematosus 384 neuropathy 368 diabetic retinopathy 314 cancer 309 GAD 268 atherosclerosis 259 proteinuria 256 IDD 249 glucose intolerance 223 gestational diabetes mellitus 215 Graves' disease 211 renal failure 200 autonomic neuropathy 190 insulinoma 180 depression 178 metabolic syndrome 157 virus infection 156 hypothyroidism 154 hyperinsulinemia 153 autoimmune thyroid disease 151 chronic disease 150 ketosis 150 diabetic neuropathy 138 asthma 138 Hashimoto's thyroiditis 137 inflammatory bowel disease 136 dyslipidemia 135 Pancreas 131 DM1 131 Pancreas 130 peripheral neuropathy 128 Addison's disease 123 Addison's disease 122 INS 122 osteoporosis 121 Crohn's disease 120 stroke 119 encephalomyelitis 119 coronary artery disease 112 infectious diseases 112 vascular disease 110 psoriasis 108 tumor 108 prediabetes 107 coronary heart disease 105 chronic renal failure 103 hyperlipidemia 99 autoimmune thyroiditis 99 thyroiditis 96 vitamin D deficiency 93 arthritis 93 SEM 88 pancreatitis 86 myocardial infarction 85 lupus 80 mimicry 79 coma 79 vitiligo 78 diabetic cardiomyopathy 78 cognitive impairment 76 cold 74 lupus 72 more...

Symptom pain 142 overweight 120 polyuria 74 abdominal pain 73 diarrhea 67 vomiting 65 fatigue 62 polydipsia 62 seizures 57 weakness 52 nausea 50 ketonuria 46 hepatomegaly 44 exhaustion 41 discomfort 31 headache 25 starvation 22 respiratory distress 20 low back pain 19 anesthesia 18 cerebellar ataxia 18 ataxia 18 lethargy 17 angina 17 anorexia 17 discomfort 17 thinning 16 nausea and vomiting 16 dyspnea 14 back pain 14 stigma 13 chest pain 12 dizziness 12 myalgia 11 tremor 11 hunger 10 sleepiness 10 constipation 10 Ill 9 muscle stiffness 8 bloating 8 flushing 8 cough 8 hypothermia 8 collapse 7 dysarthria 7 chorea 7 cachexia 6 spasm 6 myoclonus 6 paresthesia 6 arthralgia 6 tachypnea 6 distraction 6 asthenia 6 numbness 6 erythema 6 enuresis 5 Cushingoid 5 Cushingoid 5 dry skin 5 tinnitus 5 functional recovery 5 leg pain 5 analgesia 4 splenomegaly 4 pallor 4 muscle rigidity 4 syncope 4 abdominal discomfort 4 memory loss 4 incoordination 4 hypotonia 4 spasticity 4 vertigo 3 ophthalmoplegia 3 rigors 3 hypoproteinemia 3 agitation 3 tense 3 more...

Drug IFN-gamma 207 IL-2 156 DM1 130 Glucagon 63 lysine 50 Cardiovasc 47 Dermatol 39 CSF 33 ROS 28 Albumin 28 Dial 24 vitamin E 21 Pramlintide 20 CPR 19 Insulin glargine 18 ADM 18 ascorbate 17 Growth hormone 17 Growth hormone 17 Nephron 16 ROC 15 Asthma 15 Angiotensin II 13 PTH 13 Bifidobacterium 13 MAP 12 niacin 12 Insulin detemir 12 caffeine 11 Exenatide 11 nitroglycerin 10 Monit 9 Insulin aspart 9 CTX 9 Lantus 9 Insulin lispro 8 Nitric Oxide 8 Liraglutide 8 p75 8 Fluorescein 8 Nephron 8 Insulin glulisine 7 Tacrolimus 7 Spectrum 7 IL-1ra 7 Prednisone 7 Diurnal 7 lactose 7 NAG 6 Fluorescein 6 TAT 6 Gliclazide 6 ABC 6 Simvastatin 6 Captopril 6 DMI 6 Humalog 6 CTX 5 Rituximab 5 NADH 5 Portal 5 BCG vaccine 5 Leaf 5 Gel 5 CCL 5 EPI 5 CTX 5 Humulin 5 PDL 5 Medalist 5 IFN-beta 5 Retinoic acid 5 Vitamin E 4 Asn 4 Activin 4 Aminoguanidine 4 Imatinib 4 Glutathione 4 Indomethacin 3 Prolastin 3 more...

Enzyme renin 144 ACE 132 mitogen-activated protein kinase 115 superoxide dismutase 90 transglutaminase 80 glutamate decarboxylase 75 thyroid peroxidase 74 ATPase 73 caspase-3 69 catalase 63 protein kinase 62 ERK 60 glucokinase 52 protein kinase C 48 NO synthase 46 APC 45 AMP-activated protein kinase 44 focal adhesion kinase 41 luciferase 39 aldose reductase 39 alanine aminotransferase 37 NADPH oxidase 35 collagenase 35 alkaline phosphatase 34 peroxidase 33 proteasome 33 NADPH oxidase 33 reverse transcriptase 33 lipase 32 glutathione peroxidase 28 aspartate aminotransferase 26 trypsin 25 21-hydroxylase 25 calcineurin 22 lipoprotein lipase 22 granzyme B 22 thrombin 20 alpha-glucosidase 20 CPR 19 lactate dehydrogenase 19 lysozyme 18 PARP 17 glucose-6-phosphatase 17 NOS 16 caspase-1 15 AMPK 15 complex I 15 AMPK 15 furin 15 MIP 14 phosphatidylinositol 3-kinase 14 creatine kinase 13 ACS 12 aldehyde dehydrogenase 12 IKK 12 hexokinase 12 pyruvate dehydrogenase 11 phospholipase C 11 phosphoenolpyruvate carboxykinase 11 phosphoinositide 3-kinase 11 tissue plasminogen activator 10 dipeptidyl peptidase IV 10 beta-galactosidase 10 elastase 10 MAP 10 MEK 9 MMP 9 hyaluronidase 9 pyruvate dehydrogenase 9 pyruvate dehydrogenase 9 glucose-6-phosphate dehydrogenase 8 AST 8 phosphoenolpyruvate carboxykinase 8 plasmin 8 phospholipase A2 8 phosphoenolpyruvate carboxykinase 8 GSK 8 RNA polymerase 8 paraoxonase 8 tyrosine hydroxylase 8 more...

Compound glucose 4924 Clin 2202 Dec 1531 Insulin 863 DNA 581 creatinine 357 oxygen 350 sodium 297 Diabetol 281 Diabetol 266 calcium 265 nitric oxide 229 vitamin D 224 TNF 207 STZ 190 water 190 arginine 173 acetate 120 ATP 105 IAA 101 IAA 101 zinc 100 potassium 94 Asp 87 nicotinamide 84 His 82 Vitamin D 80 alloxan 77 Cardiol 73 TSH 73 lysine 71 phosphate 70 alanine 68 iron 66 Glucagon 63 leucine 63 tyrosine 62 urea 59 nitrogen 59 iodine 57 PEG 52 salt 51 Thyroid 47 galactose 45 serine 45 hydrogen 44 GSH 44 NKT 44 GSH 44 Optimal 44 aspartic acid 43 methionine 43 Metformin 42 Metformin 42 Pac 42 aspartic acid 41 glycerol 40 threonine 39 aspartic acid 39 aspartic acid 39 aldosterone 39 sulfate 38 PEG 37 ADP 37 copper 36 Hemoglobin 36 ethanol 34 tryptophan 33 CO2 31 ADP 31 cysteine 31 ADP 31 retinoic acid 30 Angiotensin II 30 glutamate 30 tryptophan 29 noradrenaline 29 nitrate 29 GABA 29 NAD 28 more...

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