Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011854 (type 1 diabetes)
20,749 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
insulin 8654
IDDM 2220
Sep 1225
HLA 1013
cytokine 843
hemoglobin 814
NOD 805
CD4 673
NIDDM 620
glucagon 618
Mol 602
albumin 539
glutamic acid decarboxylase 514
CD8 441
autoantigen 436
DR4 326
GAD65 325
IA-2 318
DR3 292
IL-10 287
gut 285
major histocompatibility complex 278
GAD 268
interferon 252
MHC 250
IDD 249
IFN 233
human leukocyte antigen 231
proinsulin 221
DQB1 220
IFN-gamma 217
HLA class II 208
TNF 207
CD25 202
IL-4 199
HLA-DR 197
She 191
thymus 189
IL-6 186
collagen 175
more...
Disease
type 1 diabetes 20749
diabetes 11648
type 2 diabetes 2930
hypoglycemia 1517
hyperglycemia 1503
autoimmune disease 1045
renal disease 918
NOD 805
diabetic nephropathy 721
hypertension 700
obesity 623
retinopathy 610
diabetic ketoacidosis 578
rheumatoid arthritis 523
multiple sclerosis 493
microalbuminuria 429
cardiovascular disease 399
celiac disease 394
systemic lupus erythematosus 384
neuropathy 368
diabetic retinopathy 314
cancer 309
GAD 268
atherosclerosis 259
proteinuria 256
IDD 249
glucose intolerance 223
gestational diabetes mellitus 215
Graves' disease 211
renal failure 200
autonomic neuropathy 190
insulinoma 180
depression 178
metabolic syndrome 157
virus infection 156
hypothyroidism 154
hyperinsulinemia 153
autoimmune thyroid disease 151
chronic disease 150
ketosis 150
more...
Symptom
pain 142
overweight 120
polyuria 74
abdominal pain 73
diarrhea 67
vomiting 65
polydipsia 62
fatigue 62
seizures 57
weakness 52
nausea 50
ketonuria 46
hepatomegaly 44
exhaustion 41
discomfort 31
headache 25
starvation 22
respiratory distress 20
low back pain 19
anesthesia 18
cerebellar ataxia 18
ataxia 18
lethargy 17
anorexia 17
angina 17
discomfort 17
nausea and vomiting 16
thinning 16
back pain 14
dyspnea 14
stigma 13
dizziness 12
chest pain 12
tremor 11
myalgia 11
hunger 10
constipation 10
sleepiness 10
Ill 9
cough 8
more...
Drug
IFN-gamma 207
IL-2 156
DM1 130
Glucagon 63
lysine 50
Cardiovasc 47
Dermatol 39
CSF 33
ROS 28
Albumin 28
Dial 24
vitamin E 21
Pramlintide 20
CPR 19
Insulin glargine 18
ADM 18
ascorbate 17
Growth hormone 17
Growth hormone 17
Nephron 16
ROC 15
Asthma 15
Bifidobacterium 13
Angiotensin II 13
PTH 13
MAP 12
niacin 12
Insulin detemir 12
caffeine 11
Exenatide 11
nitroglycerin 10
Monit 9
CTX 9
Insulin aspart 9
Lantus 9
Insulin lispro 8
p75 8
Nephron 8
Nitric Oxide 8
Liraglutide 8
more...
Enzyme
renin 144
ACE 132
mitogen-activated protein kinase 115
superoxide dismutase 90
transglutaminase 80
glutamate decarboxylase 75
thyroid peroxidase 74
ATPase 73
caspase-3 69
catalase 63
protein kinase 62
ERK 60
glucokinase 52
protein kinase C 48
NO synthase 46
APC 45
AMP-activated protein kinase 44
focal adhesion kinase 41
aldose reductase 39
luciferase 39
alanine aminotransferase 37
NADPH oxidase 35
collagenase 35
alkaline phosphatase 34
peroxidase 33
NADPH oxidase 33
proteasome 33
reverse transcriptase 33
lipase 32
glutathione peroxidase 28
aspartate aminotransferase 26
21-hydroxylase 25
trypsin 25
lipoprotein lipase 22
calcineurin 22
granzyme B 22
thrombin 20
alpha-glucosidase 20
CPR 19
lactate dehydrogenase 19
more...
Compound
glucose 4924
Clin 2202
Dec 1531
Insulin 863
DNA 581
creatinine 357
oxygen 350
sodium 297
Diabetol 281
Diabetol 266
calcium 265
nitric oxide 229
vitamin D 224
TNF 207
water 190
STZ 190
arginine 173
acetate 120
ATP 105
IAA 101
IAA 101
zinc 100
potassium 94
Asp 87
nicotinamide 84
His 82
Vitamin D 80
alloxan 77
TSH 73
Cardiol 73
lysine 71
phosphate 70
alanine 68
iron 66
leucine 63
Glucagon 63
tyrosine 62
urea 59
nitrogen 59
iodine 57
more...