Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011854 (
type 1 diabetes
)
20,749
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
insulin
8654
IDDM
2220
Sep
1225
HLA
1013
cytokine
843
hemoglobin
814
NOD
805
CD4
673
NIDDM
620
glucagon
618
Mol
602
albumin
539
glutamic acid decarboxylase
514
CD8
441
autoantigen
436
DR4
326
GAD65
325
IA-2
318
DR3
292
IL-10
287
gut
285
major histocompatibility complex
278
GAD
268
interferon
252
MHC
250
IDD
249
IFN
233
human leukocyte antigen
231
proinsulin
221
DQB1
220
IFN-gamma
217
HLA class II
208
TNF
207
CD25
202
IL-4
199
HLA-DR
197
She
191
thymus
189
IL-6
186
collagen
175
more...
Disease
type 1 diabetes
20749
diabetes
11648
type 2 diabetes
2930
hypoglycemia
1517
hyperglycemia
1503
autoimmune disease
1045
renal disease
918
NOD
805
diabetic nephropathy
721
hypertension
700
obesity
623
retinopathy
610
diabetic ketoacidosis
578
rheumatoid arthritis
523
multiple sclerosis
493
microalbuminuria
429
cardiovascular disease
399
celiac disease
394
systemic lupus erythematosus
384
neuropathy
368
diabetic retinopathy
314
cancer
309
GAD
268
atherosclerosis
259
proteinuria
256
IDD
249
glucose intolerance
223
gestational diabetes mellitus
215
Graves' disease
211
renal failure
200
autonomic neuropathy
190
insulinoma
180
depression
178
metabolic syndrome
157
virus infection
156
hypothyroidism
154
hyperinsulinemia
153
autoimmune thyroid disease
151
chronic disease
150
ketosis
150
more...
Symptom
pain
142
overweight
120
polyuria
74
abdominal pain
73
diarrhea
67
vomiting
65
polydipsia
62
fatigue
62
seizures
57
weakness
52
nausea
50
ketonuria
46
hepatomegaly
44
exhaustion
41
discomfort
31
headache
25
starvation
22
respiratory distress
20
low back pain
19
anesthesia
18
cerebellar ataxia
18
ataxia
18
lethargy
17
anorexia
17
angina
17
discomfort
17
nausea and vomiting
16
thinning
16
back pain
14
dyspnea
14
stigma
13
dizziness
12
chest pain
12
tremor
11
myalgia
11
hunger
10
constipation
10
sleepiness
10
Ill
9
cough
8
more...
Drug
IFN-gamma
207
IL-2
156
DM1
130
Glucagon
63
lysine
50
Cardiovasc
47
Dermatol
39
CSF
33
ROS
28
Albumin
28
Dial
24
vitamin E
21
Pramlintide
20
CPR
19
Insulin glargine
18
ADM
18
ascorbate
17
Growth hormone
17
Growth hormone
17
Nephron
16
ROC
15
Asthma
15
Bifidobacterium
13
Angiotensin II
13
PTH
13
MAP
12
niacin
12
Insulin detemir
12
caffeine
11
Exenatide
11
nitroglycerin
10
Monit
9
CTX
9
Insulin aspart
9
Lantus
9
Insulin lispro
8
p75
8
Nephron
8
Nitric Oxide
8
Liraglutide
8
more...
Enzyme
renin
144
ACE
132
mitogen-activated protein kinase
115
superoxide dismutase
90
transglutaminase
80
glutamate decarboxylase
75
thyroid peroxidase
74
ATPase
73
caspase-3
69
catalase
63
protein kinase
62
ERK
60
glucokinase
52
protein kinase C
48
NO synthase
46
APC
45
AMP-activated protein kinase
44
focal adhesion kinase
41
aldose reductase
39
luciferase
39
alanine aminotransferase
37
NADPH oxidase
35
collagenase
35
alkaline phosphatase
34
peroxidase
33
NADPH oxidase
33
proteasome
33
reverse transcriptase
33
lipase
32
glutathione peroxidase
28
aspartate aminotransferase
26
21-hydroxylase
25
trypsin
25
lipoprotein lipase
22
calcineurin
22
granzyme B
22
thrombin
20
alpha-glucosidase
20
CPR
19
lactate dehydrogenase
19
more...
Compound
glucose
4924
Clin
2202
Dec
1531
Insulin
863
DNA
581
creatinine
357
oxygen
350
sodium
297
Diabetol
281
Diabetol
266
calcium
265
nitric oxide
229
vitamin D
224
TNF
207
water
190
STZ
190
arginine
173
acetate
120
ATP
105
IAA
101
IAA
101
zinc
100
potassium
94
Asp
87
nicotinamide
84
His
82
Vitamin D
80
alloxan
77
TSH
73
Cardiol
73
lysine
71
phosphate
70
alanine
68
iron
66
leucine
63
Glucagon
63
tyrosine
62
urea
59
nitrogen
59
iodine
57
more...