Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0011854 (type 1 diabetes)
20,749 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein insulin 8654 IDDM 2220 Sep 1225 HLA 1013 cytokine 843 hemoglobin 814 NOD 805 CD4 673 NIDDM 620 glucagon 618 Mol 602 albumin 539 glutamic acid decarboxylase 514 CD8 441 autoantigen 436 DR4 326 GAD65 325 IA-2 318 DR3 292 IL-10 287 gut 285 major histocompatibility complex 278 GAD 268 interferon 252 MHC 250 IDD 249 IFN 233 human leukocyte antigen 231 proinsulin 221 DQB1 220 IFN-gamma 217 HLA class II 208 TNF 207 CD25 202 IL-4 199 HLA-DR 197 She 191 thymus 189 IL-6 186 collagen 175 tumor necrosis factor 170 HDL 170 IL-2 155 DQ2 149 renin 144 MHC class II 142 lymphoid 139 growth hormone 139 TNF-alpha 138 TCR 138 DM1 130 chemokine 128 leptin 124 STZ 123 HLA-DQ 122 DRB1 121 tyrosine phosphatase 118 IgA 117 endoplasmic reticulum 117 HLA-DR3 116 Pol 116 interferon-gamma 112 DQA1 111 ATP 105 PTPN22 102 protein tyrosine phosphatase 101 Fas 99 caspase-3 96 somatostatin 96 CTLA-4 95 inducible nitric oxide synthase 93 T cell receptor 93 IL-1 93 IL-17 91 amylin 89 ACE 89 CTLA4 85 HLA-DRB1 84 HLA-DR4 83 Cytokine 82 nitric oxide synthase 80 glutamate decarboxylase 75 insulin receptor 74 MHC class I 72 angiotensin II 72 ATPase 71 preproinsulin 70 lipopolysaccharide 70 IGF-I 69 C-reactive protein 69 superoxide dismutase 68 tissue transglutaminase 66 adiponectin 65 HLA class I 64 MRI 63 HLA-DQB1 62 GFR 60 fibrinogen 59 CD40 59 CD28 58 thyroglobulin 58 FOXP3 58 CXCL10 57 vitamin D receptor 57 catalase 56 vascular endothelial growth factor 55 GLP-1 receptor 55 thyroid peroxidase 54 interleukin-2 53 HLA-A 53 glucokinase 52 TGF-beta 51 serum albumin 51 PD-1 50 amylase 49 glucose transporter 49 insulin-like growth factor 48 Bcl-2 48 fibronectin 48 IDDM1 47 GLP-1 47 interleukin-4 47 phosphatase 47 islet-specific glucose-6-phosphatase catalytic subunit-related protein 46 pancreatic polypeptide 45 GAD67 45 osteocalcin 45 MODY 44 CD86 44 human leucocyte antigen 43 CD80 43 MAPK 42 IGF-1 42 ANOVA 42 Glutamic acid decarboxylase 42 GSH 41 peptidase 41 telomeric 41 IL-18 41 INS-1 41 polypeptide 41 p38 41 TLR4 41 B18 40 Leptin 40 PDX-1 40 chronic renal failure 40 tumor necrosis factor alpha 39 aldose reductase 39 Fas ligand 39 HLA-B 39 perforin 39 RIP 38 IFIH1 38 microsomal 38 autoimmune regulator 37 casein 37 HLA-DQA1 36 glycoprotein 36 IL2RA 36 more...

Disease type 1 diabetes 20749 diabetes 11648 type 2 diabetes 2930 hypoglycemia 1517 hyperglycemia 1503 autoimmune disease 1045 renal disease 918 NOD 805 diabetic nephropathy 721 hypertension 700 obesity 623 retinopathy 610 diabetic ketoacidosis 578 rheumatoid arthritis 523 multiple sclerosis 493 microalbuminuria 429 cardiovascular disease 399 celiac disease 394 systemic lupus erythematosus 384 neuropathy 368 diabetic retinopathy 314 cancer 309 GAD 268 atherosclerosis 259 proteinuria 256 IDD 249 glucose intolerance 223 gestational diabetes mellitus 215 Graves' disease 211 renal failure 200 autonomic neuropathy 190 insulinoma 180 depression 178 metabolic syndrome 157 virus infection 156 hypothyroidism 154 hyperinsulinemia 153 autoimmune thyroid disease 151 ketosis 150 chronic disease 150 diabetic neuropathy 138 asthma 138 Hashimoto's thyroiditis 137 inflammatory bowel disease 136 dyslipidemia 135 DM1 131 Pancreas 131 Pancreas 130 peripheral neuropathy 128 Addison's disease 123 Addison's disease 122 INS 122 osteoporosis 121 Crohn's disease 120 encephalomyelitis 119 stroke 119 coronary artery disease 112 infectious diseases 112 vascular disease 110 tumor 108 psoriasis 108 prediabetes 107 coronary heart disease 105 chronic renal failure 103 hyperlipidemia 99 autoimmune thyroiditis 99 thyroiditis 96 arthritis 93 vitamin D deficiency 93 SEM 88 pancreatitis 86 myocardial infarction 85 lupus 80 mimicry 79 coma 79 vitiligo 78 diabetic cardiomyopathy 78 cognitive impairment 76 cold 74 ischemia 72 heart failure 72 lupus 72 SCID 71 polyneuropathy 68 metabolic disorder 67 myocardial ischemia 67 influenza 65 coxsackievirus 63 glomerulosclerosis 62 enteropathy 61 NPH 59 preeclampsia 59 heart disease 59 deafness 59 blindness 59 hepatitis 57 epilepsy 57 myasthenia gravis 55 MODY 54 hyperthyroidism 53 cardiomyopathy 53 plaque 53 anemia 52 malnutrition 52 IDDM2 52 cystic fibrosis 50 cytomegalovirus 49 Alzheimer's disease 49 chronic pancreatitis 48 pernicious anemia 48 Infection 48 Best 48 adrenal insufficiency 47 ulcerative colitis 46 PSS 46 proliferative diabetic retinopathy 44 lymphopenia 44 dehydration 44 West 43 immunodeficiency 43 gastritis 42 renal insufficiency 41 GSH 41 optic atrophy 41 hypoparathyroidism 41 periodontitis 40 cirrhosis 40 sepsis 40 diabetes insipidus 40 eating disorder 40 Mycobacterium 40 hypercholesterolemia 39 Wolfram syndrome 39 fatty liver 39 myocarditis 39 primary biliary cirrhosis 38 sepsis 38 graft-versus-host disease 38 tuberculosis 38 candidiasis 37 peripheral vascular disease 37 breast cancer 37 aggression 37 encephalopathy 36 tetanus 36 goiter 36 polycystic ovary syndrome 36 schizophrenia 36 APC 36 PGA 36 periodontal disease 35 uremia 35 pneumonia 35 Poland 34 chronic hepatitis 34 malabsorption 34 colitis 34 glomerulopathy 33 essential hypertension 33 melanoma 33 more...

Symptom pain 142 overweight 120 polyuria 74 abdominal pain 73 diarrhea 67 vomiting 65 polydipsia 62 fatigue 62 seizures 57 weakness 52 nausea 50 ketonuria 46 hepatomegaly 44 exhaustion 41 discomfort 31 headache 25 starvation 22 respiratory distress 20 low back pain 19 anesthesia 18 ataxia 18 cerebellar ataxia 18 discomfort 17 anorexia 17 angina 17 lethargy 17 nausea and vomiting 16 thinning 16 dyspnea 14 back pain 14 stigma 13 dizziness 12 chest pain 12 myalgia 11 tremor 11 hunger 10 sleepiness 10 constipation 10 Ill 9 bloating 8 flushing 8 hypothermia 8 cough 8 muscle stiffness 8 collapse 7 chorea 7 dysarthria 7 numbness 6 myoclonus 6 cachexia 6 paresthesia 6 spasm 6 arthralgia 6 tachypnea 6 distraction 6 asthenia 6 erythema 6 Cushingoid 5 leg pain 5 functional recovery 5 Cushingoid 5 tinnitus 5 dry skin 5 enuresis 5 abdominal discomfort 4 pallor 4 incoordination 4 muscle rigidity 4 syncope 4 splenomegaly 4 memory loss 4 hypotonia 4 analgesia 4 spasticity 4 rigors 3 vertigo 3 agitation 3 ophthalmoplegia 3 paresis 3 Gastrointestinal symptoms 3 hypoproteinemia 3 neurological disability 3 Depressive symptoms 3 tense 3 Neuropathic pain 3 insomnia 3 sore throat 3 Wind 3 wheezing 2 chills 2 hemiplegia 2 frequent urination 2 forgetfulness 2 sneezing 2 hypocapnia 2 hyperemesis gravidarum 2 regurgitation 2 anosmia 2 decreased appetite 2 Tissue sensitivity 2 acute abdominal pain 2 urinary frequency 2 dental pain 2 acute stress 2 emaciation 2 right upper quadrant pain 2 acidity 2 blurred vision 2 facial pain 2 fever of unknown origin 2 epigastric pain 2 skin irritation 2 heartburn 1 abdominal cramps 1 masculinization 1 hip pain 1 hoarseness 1 hypercapnia 1 partial seizure 1 hyperesthesia 1 shortness of breath 1 leg edema 1 microbial colonization 1 ENT 1 bone pain 1 general problem 1 neck pain 1 jaw pain 1 thirsty 1 skin damage 1 dark urine 1 physical exhaustion 1 retching 1 exertional dyspnea 1 colic 1 alexithymia 1 apathy 1 chronic constipation 1 photophobia 1 excessive sweating 1 groin pain 1 physical appearance 1 HSA 1 lassitude 1 chronic cough 1 feeling faint 1 Gastrointestinal discomfort 1 corpulence 1 hyperemesis 1 intestinal bleeding 1 hopelessness 1 otalgia 1 dysosmia 1 Fluctuation 1 fasciculation 1 visual hallucination 1 joint stiffness 1 disturbed balance 1 disturbance of sensation 1 acute abdomen 1 more...

Drug IFN-gamma 207 IL-2 156 DM1 130 Glucagon 63 lysine 50 Cardiovasc 47 Dermatol 39 CSF 33 ROS 28 Albumin 28 Dial 24 vitamin E 21 Pramlintide 20 CPR 19 ADM 18 Insulin glargine 18 Growth hormone 17 Growth hormone 17 ascorbate 17 Nephron 16 Asthma 15 ROC 15 Bifidobacterium 13 PTH 13 Angiotensin II 13 niacin 12 MAP 12 Insulin detemir 12 Exenatide 11 caffeine 11 nitroglycerin 10 Lantus 9 CTX 9 Monit 9 Insulin aspart 9 p75 8 Insulin lispro 8 Nitric Oxide 8 Nephron 8 Liraglutide 8 Fluorescein 8 Prednisone 7 Diurnal 7 Tacrolimus 7 IL-1ra 7 Spectrum 7 Insulin glulisine 7 lactose 7 TAT 6 DMI 6 Humalog 6 Gliclazide 6 NAG 6 Captopril 6 Fluorescein 6 Simvastatin 6 ABC 6 CTX 5 IFN-beta 5 CTX 5 Leaf 5 CCL 5 Retinoic acid 5 EPI 5 Humulin 5 BCG vaccine 5 Medalist 5 PDL 5 Rituximab 5 NADH 5 Gel 5 Portal 5 Vitamin E 4 Activin 4 Aminoguanidine 4 Asn 4 Imatinib 4 Glutathione 4 Glide 3 Ginseng 3 EPA 3 Kenyan 3 ENT 3 EE2 3 Anakinra 3 Ouabain 3 Fragment 3 Award 3 Xanthium 3 Sandostatin 3 Symlin 3 Vitamin B12 3 pyridoxal phosphate 3 Ramipril 3 FAD 3 Bayer 3 citric acid 3 Dakar 3 Prolastin 3 Check 3 AMC 3 Mutagen 3 Indomethacin 3 Vitamin A 3 Sandostatin 3 Sodium alginate 2 Honey 2 CIA 2 Thyroglobulin 2 ACT 2 Iohexol 2 RFP 2 Gleevec 2 Darbepoetin alfa 2 Pleconaril 2 Adenosine deaminase 2 Lisofylline 2 Antithrombin III 2 Alanine 2 Infliximab 2 Parkin 2 Isotretinoin 2 Photofrin 2 Iodixanol 2 GHRP 2 Heme 2 Lovastatin 2 Spectrum 2 Camp 2 PCP 2 NBT 2 Epoetin 2 Salbutamol 2 Sinemet 2 MRC 2 IL-11 2 Abatacept 2 Methyldopa 2 Infliximab 2 Beta-2 2 Ximelagatran 2 Abetimus sodium 2 G-CSF 2 Parkin 2 Alliance 2 ampicillin 2 GRF 2 Erlotinib 2 APD 2 CET 2 Neoral 2 Ranitidine 2 Atropine 2 Trental 1 Perindopril 1 Ontak 1 Irinotecan 1 Amoxicillin 1 Methylprednisolone 1 Caspofungin 1 more...

Enzyme renin 144 ACE 132 mitogen-activated protein kinase 115 superoxide dismutase 90 transglutaminase 80 glutamate decarboxylase 75 thyroid peroxidase 74 ATPase 73 caspase-3 69 catalase 63 protein kinase 62 ERK 60 glucokinase 52 protein kinase C 48 NO synthase 46 APC 45 AMP-activated protein kinase 44 focal adhesion kinase 41 aldose reductase 39 luciferase 39 alanine aminotransferase 37 NADPH oxidase 35 collagenase 35 alkaline phosphatase 34 peroxidase 33 proteasome 33 reverse transcriptase 33 NADPH oxidase 33 lipase 32 glutathione peroxidase 28 aspartate aminotransferase 26 trypsin 25 21-hydroxylase 25 lipoprotein lipase 22 calcineurin 22 granzyme B 22 alpha-glucosidase 20 thrombin 20 lactate dehydrogenase 19 CPR 19 lysozyme 18 glucose-6-phosphatase 17 PARP 17 NOS 16 AMPK 15 furin 15 AMPK 15 caspase-1 15 complex I 15 MIP 14 phosphatidylinositol 3-kinase 14 creatine kinase 13 ACS 12 IKK 12 hexokinase 12 aldehyde dehydrogenase 12 phospholipase C 11 pyruvate dehydrogenase 11 phosphoenolpyruvate carboxykinase 11 phosphoinositide 3-kinase 11 dipeptidyl peptidase IV 10 MAP 10 beta-galactosidase 10 elastase 10 tissue plasminogen activator 10 MMP 9 MEK 9 pyruvate dehydrogenase 9 pyruvate dehydrogenase 9 hyaluronidase 9 phosphoenolpyruvate carboxykinase 8 plasmin 8 arginase 8 endonuclease 8 RNA polymerase 8 glucose-6-phosphate dehydrogenase 8 paraoxonase 8 glyceraldehyde-3-phosphate dehydrogenase 8 paraoxonase 8 phosphoenolpyruvate carboxykinase 8 GSK 8 hexosaminidase 8 AST 8 phospholipase A2 8 tyrosine hydroxylase 8 RNase 7 gamma-glutamyl transpeptidase 7 glucose oxidase 7 caspase-8 7 pyruvate kinase 7 CPT 7 caspase-9 7 heme oxygenase 7 acetylcholinesterase 7 cathepsin D 7 adenylate cyclase 7 kallikrein 7 glutathione reductase 7 hyaluronidase 7 guanylate cyclase 7 RNase 7 GLO 6 phosphodiesterase 6 glutathione S-transferase 6 PRA 6 indoleamine 2,3-dioxygenase 6 TAT 6 thromboplastin 6 cholinesterase 6 carboxypeptidase E 6 AGT 5 citrate synthase 5 methylenetetrahydrofolate reductase 5 xanthine oxidase 5 glyceraldehyde-3-phosphate dehydrogenase 5 CPT 5 methylenetetrahydrofolate reductase 5 angiotensin-converting enzyme 2 5 CPT 5 glyceraldehyde-3-phosphate dehydrogenase 5 CAD 5 BMT 5 glyceraldehyde-3-phosphate dehydrogenase 5 neutrophil elastase 5 CAD 5 CAD 5 glyceraldehyde-3-phosphate dehydrogenase 5 protein phosphatase 2A 5 MMP-3 4 peroxiredoxin 4 carbonic anhydrase 4 STR 4 ATP synthase 4 12-lipoxygenase 4 PAH 4 15-lipoxygenase 4 succinate dehydrogenase 4 acid phosphatase 4 KAT 4 transcriptase 4 cathepsin K 4 phosphofructokinase 4 TdT 4 calcium pump 4 phosphorylase 4 C3 convertase 4 adenosine deaminase 4 soluble epoxide hydrolase 4 adenosine deaminase 4 chymotrypsin 4 glycerol-3-phosphate dehydrogenase 3 glycerol-3-phosphate dehydrogenase 3 meprin 3 urokinase-type plasminogen activator 3 ceruloplasmin 3 demethylase 3 deoxyhypusine synthase 3 phosphoglycerate kinase 3 CD10 3 peptidylarginine deiminase 3 more...

Compound glucose 4924 Clin 2202 Dec 1531 Insulin 863 DNA 581 creatinine 357 oxygen 350 sodium 297 Diabetol 281 Diabetol 266 calcium 265 nitric oxide 229 vitamin D 224 TNF 207 water 190 STZ 190 arginine 173 acetate 120 ATP 105 IAA 101 IAA 101 zinc 100 potassium 94 Asp 87 nicotinamide 84 His 82 Vitamin D 80 alloxan 77 TSH 73 Cardiol 73 lysine 71 phosphate 70 alanine 68 iron 66 leucine 63 Glucagon 63 tyrosine 62 urea 59 nitrogen 59 iodine 57 PEG 52 salt 51 Thyroid 47 serine 45 galactose 45 hydrogen 44 Optimal 44 NKT 44 GSH 44 GSH 44 aspartic acid 43 methionine 43 Metformin 42 Pac 42 Metformin 42 aspartic acid 41 glycerol 40 aspartic acid 39 aspartic acid 39 threonine 39 aldosterone 39 sulfate 38 PEG 37 ADP 37 Hemoglobin 36 copper 36 ethanol 34 tryptophan 33 CO2 31 ADP 31 cysteine 31 ADP 31 retinoic acid 30 glutamate 30 Angiotensin II 30 tryptophan 29 nitrate 29 GABA 29 noradrenaline 29 NAD 28 SDS 27 GABA 27 Sodium 26 glutamic acid 26 DBA 25 DBA 25 tryptophan 25 Retinal 25 Wellcome 25 tryptophan 25 Dial 25 DBA 25 NH2 24 cAMP 24 glutamine 24 homocysteine 23 Phe 22 EDTA 21 acetone 21 EDTA 21 phosphorus 20 ACTH 20 retinol 20 DPP 20 gamma-aminobutyric acid 19 APS 18 BCR 18 MDR 18 Cholesterol 18 proline 18 FK506 18 NAD 18 MTT 17 cGMP 17 6-12 17 selenium 17 ASA 16 H2O2 16 dUTP 16 Pima 16 chromium 16 DPT 15 valine 15 Cyclosporine 15 AMP 15 Adrenal 14 BMD 14 TRH 14 Abbott 14 Resveratrol 14 carbonate 13 Mg2+ 13 Cereb 13 Fructosamine 13 Ile 13 hyaluronic acid 13 BCG 13 PMA 12 CoA 12 pentosidine 12 Gly 12 Alginate 12 superoxide radical 12 8-OHdG 12 ornithine 11 Salt 11 ornithine 11 BMC 11 MDA 11 caffeine 11 ornithine 11 DBP 11 PGE2 11 ornithine 11 Collagen 11 THP 11 ornithine 11 ACS 11 DBP 11 MAP 11 more...

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