Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011854 (
type 1 diabetes
)
20,749
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
TolerRx Inc, under license from
BTG
plc, is developing TRX-4, an anti-CD3 humanized monoclonal antibody for the potential treatment of
type 1 diabetes
and psoriasis. Phase II trials of the therapeutic antibody in
type 1 diabetes
have been completed and the company is planning a pivotal phase III trial for this indication. TolerRx is also enrolling psoriasis patients in a phase Ib clinical study of TRX-4. TRX-4 has been awarded Orphan Drug status for recent-onset
type 1 diabetes
.
...
PMID:TRX-4 (TolerRx Inc). 1659 83
