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Query: UMLS:C0011854 (type 1 diabetes)
 20,749 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Insulin-dependent diabetes mellitus (IDDM) has rarely, if ever, been reported to be an autoimmune disease associated with myasthenia gravis (MG). Two Chinese patients, one of whom was successfully treated with cyclosporin A (CyA) are reported, with discussion of pathophysiologic mechanisms involved and rationale for the treatment used.
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi 1989 Feb
PMID:Myasthenia gravis and insulin-dependent diabetes mellitus in two adolescents. 279 20

The purpose of this study was to investigate the self-reported self-management of juveniles with IDDM and the factors influencing self-management. Sixty-eight subjects, ranging from the fourth grade of primary school to the third year of junior high school, were recruited from the enrollment list of the Taipei IDDM Registry and from the list of the Kang-Tai IDDM Association. Results illustrated that patient's age, educational level, knowledge about IDDM, self-concept, and family rearing behaviors had significant associations with some aspects of self-management. Intensive health education or counselling for patients and their parents is highly recommended in order to improve their knowledge, self-management practice and psychosocial adjustment.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi
PMID:Self-management and attributes of juveniles with insulin-dependent diabetes mellitus. 777 44

The incidence of insulin-dependent diabetes (IDDM) in Chinese is much lower than for Western persons. The study was designed to determine whether Chinese children with transient hyperglycemia would develop diabetes as frequently as Western children. Ten children presenting with transient hyperglycemia were investigated using glucagon stimulation test, oral glucose tolerance test (OGTT) and i.v. glucose tolerance test (IVGTT) to estimate pancreatic insulin secretory function. They were followed up for one to three years. Islet cell antibodies and insulin autoantibodies were also measured. During the follow-up period, 2 of the 10 children developed diabetes at 1 month and 1 year, respectively, after the occurrence of transient hyperglycemia. Both of them had lower C-peptide peak level to glucagon stimulation, decreased first phase insulin release to IVGTT and a diabetic sibling. Islet cell antibodies and insulin autoantibodies were all negative except in one of the two children who later developed diabetes. Although it is still premature owing to the small sample size to conclude that Chinese children with transient hyperglycemia are less likely to develop diabetes than Western children, it is advisable to closely follow up those with a family history of IDDM who seem to be at the greatest risk.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi
PMID:Clinical implication of transient hyperglycemia in childhood. 907 82