Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011854 (type 1 diabetes)
 20,749 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The aim of the study was to determine whether IDDM affects the course of psychological adjustment in youths. The study sample included 164 children with IDDM (mean age=10.2) and their parents compared to 164 healthy controls matched for age, sex and socioeconomic status. Adjustment was measured with the Child Behavior Checklist, a parental rating scale, validated and adapted for the French population. Two-way ANOVAs on CBCL scale scores showed that scores for both internalizing and externalizing problem behaviors and the total CBCL score were significantly raised in diabetic children (p<0.001). Further comparisons on the 8 narrow-band scale scores of the CBCL indicated increased scores for diabetic children on 6 dimensions. A significant Gender x Status (IDDM versus Controls) interaction was found, supportive of higher rates of aggressive behaviors amongst male diabetic children (p<0.01). Controlling for age, no correlation was found between CBCL total, internalizing and externalizing scores and duration of IDDM or HbA1c levels within the diabetic group. Psychological adjustment to chronic illness needs to be considered with respect to both normal developmental demands as well as in the context of the specific challenges posed by the disease.
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PMID:Psychological adjustment in a french cohort of type 1 diabetic children. PEDIAB Collaborative Group. 1070 1

Diabetes mellitus type 1 (T1DM) is a chronic disease with long term consequences dictating daily struggle to maintain a good metabolic control. Children and adolescents with T1DM seem to have inferior psychological adjustment to their normal counterparts, which might be associated with glycemic control and disease duration. The aim of this study is to evaluate the psychological characteristics of children and adolescents with T1DM treated last year in the University Children Hospital in Skopje, Macedonia and to propose some response measures. For psychological evaluation we used CBCL (Child Behavior Check List), GAS (General Anxiety Scale), EPQ (Eysenck Personality Questionnaire) and MMPI-201 (Minnesota Multiphasic Personality Inventory). The results confirmed the following psychological characteristics: mild depression and anxiety, emotional instability, need for social acceptance, as well as the possible psychopathic traits. Suffering for a complex metabolic and chronic illness, these patients need psychological evaluation and intervention in the management.
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PMID:Some Psychological Aspects of T1DM in Children and Adolescents. 2744 4