Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011854 (
type 1 diabetes
)
20,749
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The development of type 1 (insulin dependent) diabetes mellitus (
IDDM
) requires a genetically susceptible host and exposure, early in life, to environmental trigger molecules that induce diabetic autoimmunity to insulin producing islet cells. We previously identified islet cell protein p69 as a candidate autoimmune target in
IDDM
. Here we describe a human genomic p69 fragment which allowed us to map the gene (
ICA1
) to chromosome 7p22.
...
PMID:ICA1 encoding p69, a protein linked to the development of type 1 diabetes, maps to human chromosome 7p22. 816 6
