Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011849 (
diabetes
)
277,896
document(s) hit in 31,850,051 MEDLINE articles (0.18 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
insulin
67475
Sep
17073
hemoglobin
6421
Mol
6177
glucagon
5794
albumin
4327
HDL
3271
cytokine
2957
collagen
2651
ATP
2550
leptin
2419
renin
2333
gut
2166
superoxide dismutase
1804
adiponectin
1803
insulin receptor
1796
C-reactive protein
1793
HLA
1637
NIDDM
1586
TNF
1568
IDDM
1535
NOD
1528
tumor necrosis factor
1518
endoplasmic reticulum
1514
STZ
1449
catalase
1358
growth hormone
1317
IL-6
1271
somatostatin
1236
CD4
1230
angiotensin II
1198
She
1158
GLP-1 receptor
1132
peptidase
1081
serum albumin
1069
aldose reductase
1049
chronic renal failure
1043
vascular endothelial growth factor
1042
peroxisome proliferator-activated receptor
1012
proinsulin
998
GSH
994
fibrinogen
974
caspase-3
973
amylin
959
nitric oxide synthase
955
glutathione peroxidase
935
ACE
905
glucose transporter
901
glucokinase
874
IRS-1
825
peroxisome proliferator-activated receptor gamma
824
GLP-1
809
Pol
785
amylase
777
mTOR
777
AMP-activated protein kinase
774
MRI
768
glucosidase
768
glutamic acid decarboxylase
762
ATPase
756
CD8
746
interleukin-6
724
DPP
713
GLUT4
698
IL-10
684
calcium channel
640
autoantigen
638
inducible nitric oxide synthase
629
interferon
622
ADP
614
alkaline phosphatase
606
PI3K
606
fibronectin
606
TNF-alpha
596
AMPK
593
p38
588
AKT
582
angiotensin receptor
581
ROS
574
AMP
573
more...
Disease
diabetes
277896
hypertension
30437
obesity
27445
type 2 diabetes
25264
hyperglycemia
15274
cardiovascular disease
13560
cancer
12555
type 1 diabetes
11648
atherosclerosis
8882
renal disease
8348
stroke
7424
metabolic syndrome
7253
hypoglycemia
6566
glucose intolerance
5620
diabetic nephropathy
5402
myocardial infarction
5227
dyslipidemia
5158
coronary artery disease
4983
heart failure
4722
hyperlipidemia
4598
retinopathy
4146
diabetic retinopathy
3858
coronary heart disease
3787
neuropathy
3603
depression
3586
hyperinsulinemia
3325
Alzheimer's disease
3250
heart disease
2973
renal failure
2850
tumor
2837
hypercholesterolemia
2763
ischemia
2714
vascular disease
2541
proteinuria
2496
myocardial ischemia
2483
gestational diabetes mellitus
2371
microalbuminuria
2171
chronic disease
2139
osteoporosis
2019
diabetic neuropathy
1965
chronic renal failure
1964
fatty liver
1858
cirrhosis
1834
asthma
1825
autoimmune disease
1739
dementia
1694
congestive heart failure
1658
rheumatoid arthritis
1637
HIV
1574
peripheral neuropathy
1563
NOD
1528
prediabetes
1465
anemia
1460
infectious diseases
1403
arthritis
1380
sepsis
1370
diabetic ketoacidosis
1353
cognitive impairment
1333
liver disease
1326
plaque
1298
chronic obstructive pulmonary disease
1279
acute myocardial infarction
1269
blindness
1245
autonomic neuropathy
1239
metabolic disorder
1236
peripheral vascular disease
1235
sepsis
1210
malnutrition
1171
tuberculosis
1162
cardiomyopathy
1098
diabetic cardiomyopathy
1088
breast cancer
1082
hepatocellular carcinoma
1039
hypothyroidism
1033
GSH
995
cataract
938
pancreatitis
935
pneumonia
922
systemic lupus erythematosus
917
multiple sclerosis
903
more...
Symptom
overweight
3482
pain
3351
angina
1337
diarrhea
767
anesthesia
732
fatigue
669
weakness
657
abdominal pain
608
headache
541
starvation
533
seizures
487
vomiting
476
nausea
470
polyuria
464
chest pain
415
dyspnea
365
respiratory distress
348
polydipsia
346
cough
342
discomfort
316
discomfort
272
constipation
258
anorexia
240
back pain
232
ketonuria
231
exhaustion
219
ataxia
210
dizziness
204
insomnia
199
hepatomegaly
187
sleepiness
187
cachexia
179
erythema
174
hunger
172
numbness
167
collapse
158
analgesia
151
functional recovery
141
ophthalmoplegia
135
thinning
131
syncope
128
nausea and vomiting
120
hypothermia
119
stigma
112
tremor
109
paresthesia
109
myalgia
106
Ill
104
shortness of breath
100
flushing
99
arthralgia
97
lethargy
93
dysarthria
93
Neuropathic pain
93
vertigo
87
low back pain
84
memory loss
81
snoring
81
spasm
79
hemoptysis
67
epigastric pain
66
hemiplegia
64
bloating
63
chills
62
cerebellar ataxia
62
hypotonia
60
Wind
59
dry eye
59
tinnitus
58
flank pain
57
acute stress
54
paresis
54
oliguria
51
dysuria
49
splenomegaly
49
Depressive symptoms
49
chorea
45
HSA
45
hypercapnia
45
hypoproteinemia
44
more...
Drug
Cardiovasc
2249
lysine
918
Glucagon
831
Dermatol
805
vitamin E
601
ROS
574
Dial
567
ascorbate
520
IFN-gamma
454
IL-2
332
Monit
303
ADM
269
NADH
242
Nephron
241
Albumin
212
caffeine
212
niacin
210
ROC
208
Angiotensin II
185
Rosiglitazone
184
Liraglutide
179
Nephron
174
CSF
172
Leaf
153
DM1
152
MAP
152
Growth hormone
147
Troglitazone
146
Growth hormone
143
nitroglycerin
143
Fructose
142
Exenatide
136
Vitamin E
135
PTH
132
Spectrum
126
Gliclazide
126
Asthma
104
Gel
101
Aminoguanidine
101
ampicillin
100
Tacrolimus
94
Glutathione
91
CTX
87
Simvastatin
81
Bifidobacterium
79
citric acid
75
Ramipril
75
lactose
73
Captopril
69
Fluorescein
68
Indomethacin
68
FAD
67
EPA
66
EPI
66
Nitric Oxide
63
ENT
63
Valsartan
62
ALA
62
ABC
61
Portal
59
Aloe
58
Clopidogrel
57
Vitamin A
56
Perindopril
56
Insulin glargine
55
Ginseng
53
Insulin detemir
52
CPR
52
AHF
52
BH4
51
CTX
51
CTX
51
Ethanol
50
Orlistat
50
Glide
49
p75
49
NAG
49
EE2
48
Fluorescein
47
Serum albumin
47
more...
Enzyme
renin
2333
superoxide dismutase
2110
mitogen-activated protein kinase
1719
protein kinase
1509
catalase
1481
ACE
1466
AMP-activated protein kinase
1310
protein kinase C
1254
aldose reductase
1062
glutathione peroxidase
942
glucokinase
875
ERK
834
ATPase
828
alanine aminotransferase
809
caspase-3
740
AMPK
646
aspartate aminotransferase
631
alkaline phosphatase
608
NADPH oxidase
606
AMPK
593
NO synthase
502
NADPH oxidase
490
lipoprotein lipase
477
alpha-glucosidase
476
focal adhesion kinase
449
peroxidase
408
luciferase
405
lactate dehydrogenase
392
glucose-6-phosphatase
383
collagenase
380
lipase
379
thrombin
377
calcineurin
369
phosphodiesterase
358
phosphoenolpyruvate carboxykinase
350
phosphatidylinositol 3-kinase
338
hexokinase
331
GSK
324
creatine kinase
319
proteasome
285
trypsin
280
acetylcholinesterase
269
phosphoenolpyruvate carboxykinase
265
PARP
259
glutathione reductase
259
ACS
259
phosphoenolpyruvate carboxykinase
257
tissue plasminogen activator
240
phosphorylase
236
glucose oxidase
230
aldehyde dehydrogenase
228
reverse transcriptase
223
AST
221
pyruvate dehydrogenase
214
glucose-6-phosphate dehydrogenase
214
adenylate cyclase
214
xanthine oxidase
198
APC
197
phosphoinositide 3-kinase
195
gamma-glutamyl transpeptidase
194
dipeptidyl peptidase IV
193
CAD
190
CAD
190
CAD
190
NOS
184
acetyl-CoA carboxylase
169
pyruvate kinase
165
pyruvate dehydrogenase
162
pyruvate dehydrogenase
162
phospholipase A2
161
glutathione S-transferase
158
complex I
156
kallikrein
153
CPT
151
ceruloplasmin
151
MEK
140
cholinesterase
139
glutamate decarboxylase
139
phospholipase C
137
caspase-1
136
more...
Compound
glucose
56842
Clin
25480
Dec
18563
Insulin
7550
oxygen
6112
DNA
5256
calcium
4894
creatinine
4532
sodium
3877
Cardiol
3869
water
3682
nitric oxide
3107
ATP
2551
STZ
2480
alloxan
2382
arginine
1973
phosphate
1740
Diabetol
1646
acetate
1616
potassium
1608
TNF
1568
urea
1385
galactose
1376
iron
1352
Diabetol
1216
tyrosine
1184
Metformin
1149
Metformin
1139
vitamin D
1139
nitrogen
1129
aldosterone
1118
lysine
1094
Pac
1075
GSH
1054
GSH
1054
zinc
1041
hydrogen
1004
ethanol
968
salt
870
cAMP
869
Glucagon
831
nicotinamide
823
His
779
Cholesterol
766
serine
754
alanine
748
leucine
730
ADP
719
DPP
713
sulfate
673
homocysteine
647
AMP
636
glycerol
625
ADP
621
ADP
614
cysteine
610
Dial
594
NAD
591
threonine
536
copper
524
glutamate
514
methionine
495
noradrenaline
458
prostacyclin
457
Angiotensin II
443
NAD
433
ASA
401
CO2
399
iodine
397
Retinal
389
TSH
388
Pima
383
glutamine
371
ACTH
362
phosphorus
362
NADPH
361
NADPH
360
Hemoglobin
359
CoA
357
Optimal
354
more...