Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011849 (
diabetes
)
277,896
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A hospital-based study was designed to find out the frequency of use of oral pills to reassess the relative incidence of adverse drug reactions (ADRS) and the possibility of drug interactions and also to review the role of physicians or hospital clinics in monitoring their use. A group of women of reproductive age attending the postpartum unit of North Bengal Medical College and Hospital and the immunization clinic for coverage of their children were interviewed during July-September, 1987. Out of 500 women studied 66 (13.2%) were using oral contraceptives (OCs). Females of younger age group used OCs more frequently (86.3%) and none above 35 years used them. The acceptance of OCs was based on doctor's recommendation in 47 users (71.21%), while for 19 (28.79%) it was based on the advice of either husband or friends or relatives. 44 (66.67%) of the users received their monthly quota of OCs free from government hospitals. OC use was not halted in spite of malnutrition (24.24%), obesity (27.27%), breathlessness on exertion (28.79%), lump in the breast (9.09%), or
diabetes
(9.09%).
Visual disturbances
were present in 12.12% of users. 17 (15.76%) of users smoked. Less than 6 months after childbirth 17 (25.76%) nursing mothers resumed OC use. 58 (87.88%) of 66 users used OCs continuously for less than 3 years, 8 (12.12%) used them continuously for 2-5 years, and none used them continuously for over 5 years. 30 OC users (45.45%) were also taking one or more drugs concurrently along with the OCs. The most frequent were oral anticoagulants, phenytoin, antitubercular drugs, chloroquine, antileprosy drugs, salbutamol, corticosteroids and some antibiotics. In all such cases the prescribing physicians never seemed to be concerned about taking the drug use history.
...
PMID:Profile of oral contraceptive usage by females of the northern part of West Bengal. 130 87
We studied the long-term outcome of 268 patients suffering from diabetic end-stage renal disease (DM-ESRD) treated with long-term haemodialysis between 1978 and 1991, with special emphasis on visual acuity as well as the heterogeneity of DM-ESRD. The 50% patient survival on haemodialysis was 60 months.
Visual disturbances
were found in 73.1% (392/536) of eyes at the start of haemodialysis. Chronological assessment of visual acuity demonstrated the stabilization of visual acuity and 87.1% (364/418) of eyes were stable, 4.8% (20/418) were improved, and 8.1% (34/418) were aggravated in the long term respectively. The change of visual acuity was frequently seen in the short term, and rapid shifts of body fluid to correct overhydration induced abrupt changes of glycaemic control as well as retraction of macular oedema. Hence it might be one of the factors affecting rapid change of visual acuity in the short term. Meanwhile, long-term deterioration of visual acuity resulted from either hypertension unresponsive to medical treatment or poor glycaemic control. Some DM-ESRD patients had only background retinopathy at the start of haemodialysis and these were likely to have the nephrosclerotic glomerular lesion. They were old, not nephrotic and had a mild degree of
diabetes
during the predialysis stage. Thus, DM-ESRD patients seem to have some heterogeneity in their clinical characteristics, and old DM-ESRD patients with only background retinopathy have the appearance of diabetic macroangiopathy rather than microangiopathy.
...
PMID:Long-term follow-up study of 268 diabetic patients undergoing haemodialysis, with special attention to visual acuity and heterogeneity. 841 59
Visual disturbance
including visual loss is a rare but devastating complication after non-ophthalmic surgery. Reported incidence of visual disturbances ranged from 0.028 to 0.2% after spine surgery and from 0.0009 to 25.6% after cardiac surgery. Ischemic optic neuropathy, central retinal artery occlusion, and cortical blindness can be involved as an etiology. After spine surgery, posterior ischemic optic neuropathy is most prevalent and risk factors included prone surgery, long operative time, massive hemorrhage and anemia. After cardiac surgery, anterior ischemic optic neuropathy is most prevalent and risk factors included age,
diabetes
, long cardiopulmonary bypass time and anemia. Anesthesiologists and surgeons should be aware of this complication and further investigations regarding etiology, prevention and managements on postoperative visual disturbances would be required.
...
PMID:[Postoperative visual disturbances after non-ophthalmic surgery]. 1970 7
Diabetes mellitus
(DM) is a common disease in the elderly population. The concept of autonomy is linked to a balance between the impairments observed in the daily activities and the availability of resources to compensate these incapacities. In the evolution of the DM, micro and macro vascular complications are commonly observed. The burden of these complications is usually proportional to the duration of the disease and the quality of glycaemic control.
Visual alteration
and progressive kidney failure requiring haemodialysis have significant impact on the functional status on the elderly diabetic patient living at home. Alterations of cardiac function and peripheral vascular disease which can ultimately lead to lower limb amputation also result in a dramatic alteration in the capacity of elderly patient to carry routine activities of daily living. The presence of DM seems to be a risk factor for cognitive decline and dementia. This article will review the usual complications of DM and link these complications to functional changes in the elderly population.
...
PMID:[Diabetes and changes in functional status of the elderly: a reality?]. 2122 10