Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011849 (diabetes)
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This study will explore a few recipes in relation to what monastic medicine considered kidney disorders. Technical terms, such as strangury, cause us difficulties in interpreting early medieval monastic medicine. The action described can vary considerably. For example, he has action for urination problems that center in the verb: (in translation) "dries out", "quietens", "expels", "moves", "provoking", and treating "retention of urine". Sometimes the term "diuretic" is used. The Lorsch monastic book of medical recipes, written around 800, employed the words "deuritica" and "diureticon" but most of monastic accounts simply say something similar to that in Reichenau Monastery's recipe book, 9th or 10th century: "urinam movet/moves the urine"; "urinam provocat/stimulates urination"; "ad difficultate urine/difficulty in urination". In order to examine the relationship between diagnosis and therapy, let us turn to a disease that is difficult even for modern medicine, diabetes. An examination of several early medieval monastic accounts reveals that they could have effectively treated diabetes.
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PMID:Kidney and urinary therapeutics in early medieval monastic medicine. 1529 38

Strychnos potatorum Linn. seeds are used in the Indian traditional system of medicine for the treatment of hepatopathy, nephropathy, gonorrhoea, leucorrhoea, gastropathy, bronchitis, chronic diarrhoea, strangury, renal and vesicle calculi, diabetes and eye diseases. The present study describes the hepatoprotective and antioxidant activities of the seed powder (SPP) and aqueous extract (SPE) of Strychnos potatorum seeds against CCl4-induced acute hepatic injury. Hepatic injury was achieved by injecting 3 ml/kg, s.c. of CCl4 in equal proportion with olive oil. Both SPP and SPE at the doses 100 and 200 mg/kg, p.o. offered significant (p < 0.001) hepatoprotective action by reducing the serum marker enzymes like serum glutamate oxaloacetate transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT). They also reduced the elevated levels of ALP and serum bilirubin. Reduced enzymic and nonenzymic antioxidant levels and elevated lipid peroxide levels were restored to normal by administration of SPP and SPE. Histopathological studies further confirmed the hepatoprotective activity of SPP and SPE when compared with the CCl4 treated control groups. The results obtained were compared with Silymarin (50 mg/kg, p.o.), the standard drug. In conclusion, SPE (200 mg/kg, p.o.) showed significant hepatoprotective activity similar to that of the standard drug, Silymarin (50 mg/kg, p.o.).
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PMID:Studies on hepatoprotective and antioxidant actions of Strychnos potatorum Linn. seeds on CCl4-induced acute hepatic injury in experimental rats. 1638 23