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Query: UMLS:C0011849 (diabetes)
 277,896 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Several medications can be used to treat patients with painful diabetic neuropathy. However, studies differ as to the efficacy of many of these agents. We hope future research will help to delineate a more exact usage of these agents in the treatment of this condition. Ischemic neuropathy as it pertains to arteriosclerosis, thromboangiitis obliterans and diabetes mellitus has been discussed in this study. The vascular anatomy of peripheral nerves has been presented. Furthermore, research has been discussed that shows diffuse ischemic results in nerve demyelination and axonal degeneration. It is hoped that this report will help to delineate the incidence and significance of ischemic neuritis in patients with peripheral vascular occlusive disease.
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PMID:Ischemic neuropathy. 282 2

Ischemic neuropathy from sources other than diabetes is less common, but can be encountered in clinical practice. Diagnosis can be challenging, and many patients may be referred to the electrodiagnostic laboratory. Overlapping mononeuritis multiplex is a common presentation, but distal symmetric polyneuropathy and monomelic neuropathy patterns can be seen. Depending on the disease associated with ischemic neuropathy, a mononeuropathy or a sensory-motor, axonal-demyelinating peripheral neuropathy may be seen as well. The treatment of ischemic neuropathy varies depending on the associated disease. Prognosis can be poor in the case of amyloidosis and the primary vasculitides. The literature is limited to cross-sectional case series and rare longitudinal studies likely related to the incidence of the diseases. Further study is needed to fully define the extent of the neurologic consequences of peripheral ischemia and its significance clinically.
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PMID:Ischemic peripheral neuropathy. 1134 13