Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011849 (diabetes)
 277,896 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Out of 1,251 patients above 65 years of age staying at the Charles Foix Hospital (prolonged hospitalization) and the St. Joseph Hospital (acute cases), 168 had one or more positive blood cultures. Urinary tract infection is a major source of septicemia due to gram negative bacilli. It is important to stress cases of septicemia due to pneumococcal pneumoniae, eschars, and other skin lesions. Mortality varies between 33 and 36%, depending upon the hospital. Collapse, although infrequent, still portends a grave prognosis (61% of cases of collapse led to death at Charles Foix Hospital). The combination of more than two risk factors considerably worsens the prognosis. Hypoproteinemia and dementia are every bit as grave as diabetes and cancer. A better isolation of the microorganisms involved in cases of septicemia in the elderly will lead to a more judicious choice of antibiotics. The administration of chemotherapy immediately after the samples were obtained remains the main guarantee of successful therapy.
 ...
PMID:[Septicemia in the elderly (author's transl)]. 2 83

Phase contrast microscopy has been used for examination of urinary sediments from 19 patients with hydronephrosis. Casts were seldom seen. A raised number of erythrocytes was seen only in association with catheter, calculi or diabetes. A raised number of leukocytes was seen in patients with bacteriuria. A striking observation was the finding of a great proportion (64%) of histiocyte-like cells in six out of 12 cases in whom a differential count was performed. The proportion of histiocyte-like cells was small (14%) in cases with bacteriuria or history of urinary tract infection.
 ...
PMID:The urinary sediment in hydronephrosis. 7 Sep 64

The prevalence of urinary tract infection was determined in 333 patients attending a diabetes mellitus outpatient clinic during a one-year period. A total of 19% of the women and 2% of the men were found to have urinary tract infections. Antibody-coated bacteria, indicating parenchymal infection, were initially present in 43% of patients and rose to 79% within a mean pretreatment period of seven weeks. In those with recurrent infection following treatment, there were more reinfections than relapses, both in those with kidney infections (67%) and those with bladder infections (57%). The high prevalence of urinary tract infection among diabetic women and the evidence of rapid parenchymal involvement emphasizes the need for clinical awareness of the problem and clarification of its consequences.
 ...
PMID:Urinary tract infections in patients with diabetes mellitus. Studies on antibody coating of bacteria. 33 37

The methodical prerequisitis and the clinical results-of simultaneous double-radionuclide determinations of renal clearances of 99mTc-DTPA (Sn) and 131I-Hippuran, using a partially shielded whole-body counter, are reported. Examination of the in vitro stability of the 99mTc-DTPA (Sn) complex by radiochromatographic separation revealed an unbound 99mTc fraction of 4.7%. The whole body measurement geometry was found over the non-shielded regions of the body to be independent of the various physiological distribution volumes of the clearance substances. The simultaneously determined clearances of 51Cr-EDTA and 99mTc-DTPA resulted in a strong linear correlation (r = 0.96; n = 20). The relation between serum creatinine concentration and 99mTc-DTPA clearance was approximately hyperbolic (r = 0.89; n = 154). In a group of normals (n = 102) the renal filtration fraction (FF - ClTc-DTPA/ClOIH) was 0.18 +/- 0.04. In a group of urological patients (n = 72) this fraction did not change appreciably before and after operations, whereas it was found increased to 0.25 and 0.24, respectively, in patients with diabetes and albuminuria or urinary tract infection (n = 37). The relative error of the clearance determination with a partially shielded whole-body counter was about 15% down to clearances of some 50 ml/min, and higher than 50% with clearances below 20 ml/min.
 ...
PMID:[Simultaneous determination of kidney glomerular and tubular partial functions with 99mTc-DTPA and 131I-hippuran using a partially shielded whole body counter]. 40 95

Emphysematous cystitis unassociated with diabetes mellitus was diagnosed in two dogs. One dog had chronic recurring urinary tract infection with aerobic and anaerboic bacteria, and the other had urinary tract infection associated with renal glucosuria. In both dogs, the cystitis was resolved with appropriate antibacterial therapy.
 ...
PMID:Nondiabetic emphysematous cystitis in two dogs. 43 43

The most important side effects of oral contraceptives (OCs) and their incidence, together with advice and monitoring of the patient at risk, are pointed out. There is a mild increase in blood pressure in longterm contraceptive use caused by increased angiotensinogen production by the liver. It is significant only for women with a history of familial hypertension, diabetes mellitus, or pre-eclampsia. Smoking increases this risk. Urinary tract infections are 25-50% more frequent in pill users. Glucose tolerance is slightly decreased. Contraceptives' diabetogenic effect is higher in women with hereditary tendency for diabetes, latent diabetes, and/or obesity. They are contraindicated in latent diabetes. Findings are contradictory in their effects on cholesterol and triglyceride serum level, but the pill is contraindicated in lipid metabolism disorders. There is an increased incidence in cholecystitis and cholelithiasis in pill-users (70-80 additional cases/100,000 user years). Liver diseases, intrahepatic cholestasis, occur rarely and benign liver tumors have not conclusively been proved to be caused by the pill. A variety of laboratory findings have been related to contraceptive use and drug interactions occur with barbiturates, rifampicin, hydantoin, and phenylbutazone. Blood coagulation is increased, partially by increased production of various blood coagulation factors; but more importantly, by a decreased synthesis of antithrombin III, a natural protective mechanism against intravascular coagulation. This increases thrombosis risk. Risk doubles with simultaneous cigarette smoking. Various epidemiological studies indicate a 5-10 fold increase in thromboembolism and thrombophlebitis, deep vein thrombosis, and pulmonary embolism. There is a correlation between contraceptive use and cerebrovascular disorders and myocardial infarction. This risk increases with age and years of pill use. The pill is contraindicated with symptoms of thrombophlebitis and thromboembolism, sickle cell anemia, proposed surgery, and longterm immobilization. Overall risk factors are not too high. Recommendations for rational pill use related to age are given and further contraindications are mentioned.
 ...
PMID:[Adverse effects of oral contraceptives]. 55 52

The obstetric performance and pregnancy outcome in 208 massively obese patients who were delivered over an eight-year period were compared with those of nonobese control subjects. The incidence of obesity in their infants was also compared. No significant increase in the incidence of urinary tract infection, diabetes, breech presentation, cesarean section, forceps delivery, or maternal and infant morbidity was noted in the obese women. Significantly increased incidences of hypertensive disorders of pregnancy (p less than 0.01), gestational diabetes (p less than 0.01), inadequate weight gain (p less than 0.001), and wound or episiotomy infection (p less than 0.05) were observed in the study group. The mean birth weight of the infants of obese women was 209 grams greater than that of the control subjects. A significantly increased number of the obese patients were delivered of excessive-sized infants. Despite this, the incidence of obesity in infants of obese women was not significantly increased at birth or six months of age. By 12 months of age, however, these infants were significantly more obese than the control infants.
 ...
PMID:Pregnancy in the massively obese: course, outcome, and obesity prognosis of the infant. 67 88

In a prospective, randomized study in 96 patients undergoing prostatic surgery (92 patients) and extensive transurethral bladder surgery (4 patients) all patients received postoperative antibiotics for five days. Following this the patients were divided into two groups. Group A received Bactrim for three months and Group B received a placebo for three months. Urine cultures were carried out six times during this three month period. In Group A, 13 patients (25%) were infected preoperatively and 9 patients (17%) postoperatively. In group B, 10 patients (22.8%) were infected preoperatively and 9 patients (20.5%) postoperatively. There was no significant difference between the results in the two groups. These and other results allow the following conclusions: 1. Routine postoperative long term treatment with antibacterial substances has no significant effect on the postoperative urinary tract infection. 2. Long term preoperative indwelling catheter treatment increases the incident of postoperative urinary tract infection. This can be prevented by operating patients early following the first urinary retention. It is confirmed that there is an increased risk of persistent urinary tract infection in patients with neurogenic bladder disturbances, preoperative ureteral dilatation, diabetes mellitus and various other complications.
 ...
PMID:[The effect of long term antibacterial treatment following prostatic surgery. A comparative study in 96 patients]. 80 30

Urine of 198 diabetics and 147 non-diabetics was examined for bacteriuria by means of the Uricult dip slide method. Prevalence of bacteriuria in diabetics (18,7%) was significantly higher than in the control group (7,6%). This increased prevalence in diabetics was due primarily to an exceedingly high prevalence in diabetic women (27%). There was no relation between bacteriuria and age, duration of diabetes, treatment for diabetes, quality of control of diabetes, symptoms of urinary tract infection or hypertension.
 ...
PMID:Bacteriuria in Black diabetics. 84 59

In search of urinary tract infections 3185 gynaecological patients and 1600 pregnant women were examined by means of TTC-Test. 12.8% of the gynaecological patients and 12% of the pregnant women showed bacteruria. A special disposition to urinary tract infection was found by patients suffering from descensus, fistula of urogenital system and by gravid women with toxaemea of pregnancy and diabetes mellitus. Infection through E. coli was found to be dominating and the germs showed a relatively high sensitivity against Chloramphenicol and Nifurantin now as before. Problems of diagnosis and therapy are discussed. The necessity of most effective screening methods, of early diagnosis and of interdisciplinary team-work is pointed out.
 ...
PMID:[Significance of urinary tract infections in gynecologic diseases and in pregnancy]. 91 92


1 2 3 4 5 6 7 8 9 10 Next >>