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Query: UMLS:C0011849 (diabetes)
 277,896 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The state of the parodontium was studied clinically and morphologically in 70 patients suffering from diabetes mellitus. Blood histamine and serotonin level was determined fluorometrically. Gingivitis was revealed in diabetic patients; the severity of inflammatory changes in the gingiva proved to depend on the duration and the severity of diabetes mellitus. Changes pointing to increase of the vaso-tissue permeability were revealed histologically. At the same time there was an increase in the blood histamine level and a tendency to reduction of serotonin level. This can serve as one of the factors causing an increase of the vascular permeability and a disturbance of microcirculation in the gingiva.
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PMID:[State of tissue-vascular permeability in diabetic patients with parodontosis]. 90 55

The prevalence of Actinobacillus actinomycetemcomitans (Aa) in subgingival plaque specimens from 26 insulin-dependent diabetes mellitus patients, 11-25 years of age, was determined between January 1987 and December 1989. One hundred and thirty subgingival plaque samples were collected with sterile periodontal curettes. The specimens were weighted, diluted, inoculated on trypticase-soy-serum-bacitracin-vancomycin agar medium (TSBV) and incubated under microacrophilic conditions. Aa was isolated from 2.3% of healthy periodontal areas in these patients, while the microorganism was found in 12.5% of the sites with gingivitis and in 2.6% of the periodontal pockets examined. Although biochemical tests used for the characterization of Aa strains showed homogeneous results, different biotypes were isolated from one or more periodontal sites in the same patient.
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PMID:Actinobacillus actinomycetemcomitans in Brazilian insulin-dependent individuals with diabetes mellitus. 130 14

Diabetic patients have been reported to be more susceptible to gingivitis and periodontitis than healthy subjects, and these diseases are commonly considered to be oral complications of diabetes. The influence of diabetes on the onset and development of periodontal disease has been studied for many years but clear agreement is still lacking on the nature of the relationship between diabetes and these oral disorders. In fact recent observational epidemiological studies suggest that diabetes should not be considered as the direct cause of periodontal disease but rather as a systemic promoting factor, able to produce conditions suitable for local agents producing gingivitis and periodontitis. The overriding oral problem in diabetes is infection, like with any of the dermal lesions in the diabetic. In fact periodontal disease is caused by specific bacteria (Bacteroides Gingivalis, Actinobacillus actinomycetemcomitans) growing in the periodontal pocket so that the bacterial products such as histolytic enzymes, endotoxins or exotoxins may exert a direct effect. Particular attention has been directed to the neutrophils and to their role in antibacterial defense. In fact a reduced phagocytosis, leukotaxis and leucocyte index have been reported in neutrophils from diabetics. The careful metabolic control was reported by most of the Authors to lower the incidence and to reduce the severity of periodontal disease. This may be related both to the improvement in leukocyte function and to a change in gingival fluid rendering it less suitable for bacterial growth. In diabetics also local factors, such as decreased pH of salivary fluid and a reduced salivary flow, seem to play an important role.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Diabetic disease and periodontal disease. Diabetes and periodontopathy]. 149 56

Conflicting reports exist in dental literature on the relationship of diabetes mellitus to periodontal disease. Among the controversies about this relation, the role played by the age of patient has been widely investigated. Some authors, in fact, reported an increased prevalence and severity of gingivitis and periodontitis in children and young individuals with insulin dependent diabetes mellitus (IDDM) in comparison to healthy subjects, while other researchers were not able to confirm this finding. In particular some authors postulated the hypothesis that the diabetic state could influence periodontal conditions just after the age of 30-35. The aim of the present study has been to verify this hypothesis. One hundred thirty-two subjects participated in this study; among them 66 were IDDM patients and 66 were healthy controls comparable to the diabetics for the main epidemiological features. In particular, control subjects were similar to the diabetics for oral hygiene level in order not to attribute eventually occurring differences by mistake to the diabetic state instead of to a not comparable amount of bacterial plaque present on the teeth. Among 66 IDDM patients 33 were younger than 30 (medium age = 14; extremes: 6-22) and were indicated as DG (young diabetics) group; others 33 were older than 30 (medium age = 45.1; extremes: 31-66) and were indicated as DA (adult diabetics) group. A similar differentiation was made in the control group obtaining, in this way, two subgroups (CG = young controls and CA = adult controls). In the diabetic groups males were 53% while among controls they represented 58%.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[The influence of the "age factor" on periodontal conditions in the diabetic patient]. 150 26

The present study was undertaken to establish the dental disease and treatment levels in 101 young insulin dependent diabetic patients in Northern Ireland. There was a significantly greater proportion of children from the higher social classes in the diabetic group. Their dental caries experience was lower than that reported for the general population and the restorative indices were high. However, those whose diabetes was diagnosed at a late stage had a higher caries experience. There was significantly more gingivitis detected in older diabetic patients, but oral hygiene status did not significantly differ with age. There was a pattern of regular dental attendance in the majority of diabetic subjects.
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PMID:Dental health of young insulin dependent diabetic subjects in Northern Ireland. 179 Apr 78

As a systemic disease, diabetes mellitus also involves alterations of oral structures as an integral part of the body. A group of 47 diabetics, 34 females and 13 males, mean age 55 years, were included in the study. Mean blood glucose was 12.6 mol/l. Results of clinical studies of oral alterations showed oral symptoms, i.e. xerostomia, to predominate in study subjects, followed by glossopyrosis, stomatopyrosis, gingivitis with hyperkeratosis and exfoliations effecting the tongue and lips. Membranes and ulcerations were less frequent in the group of diabetics under study. Along with the occurrence of metabolic and hormonal disturbances, cardiovascular diseases occupy the first place, followed by locomotor, gastrointestinal, respiratory and renal disturbances.
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PMID:[Oral manifestations in diabetes]. 181 30

In observing medical prescriptions the therapeutic diet of the diabetic children is a model of stomatologic preventive behaviour of nutrition. Compared are clinical dental statements of children, differently long diseased on diabetes mellitus and those with healthy metabolism of the same age. After 5 years restriction of sugar the dental statements of diabetic children show a third less carious destruction then the group in comparison. Gingivitis are widely spread in this group of age, but after the criteria of the sulcus-bleeding index they are less marked distinctly. Bone destructions of the marginal periodontium can be observed on bite-wing-radiograms of lateral teeth at 5.7% of patients.
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PMID:[Caries, gingivitis and periodontitis in l2- to 14-year olds under conditions of sugar restriction--research on type-1 diabetics]. 253 27

The prevalence of periodontitis was studied in a population of 157 insulin dependent diabetes mellitus patients aged 8-78 years attending the outpatients diabetic clinic of a large general hospital in Cork, Ireland. Every third diabetic patient attending the clinic was selected for examination. The dental parameters measured were plaque index (PI), gingivitis index (GI), periodontal pocket depth (PD) and periodontal attachment loss (PAL). Diabetic control was measured by estimating percentage haemoglobin glycolysation (% Hb Alc) known duration of diabetes (KDD) and insulin dependence. It was found that none of the diabetic measurements showed any consistent pattern in relation to any of the periodontal measurements. The findings are in agreement with other studies which suggest that no significant correlation between diabetic parameters and periodontal disease can be demonstrated. When the diabetic patient suffered periodontitis it was due to factors (such as genetic predisposition) other than impaired glucose metabolism.
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PMID:Diabetes mellitus and periodontal disease in an Irish population. 253 53

Systemic diseases--like diabetes mellitus--are able to injure the local and common resistance of an organism. Therefore we must expect a more intensive and severer progress of gingivitis and periodontitis in diabetic patients in comparison with a non-diabetic control-group. On the Gondar College of Medical Sciences in Northwest-Ethiopia are investigated 77 Insulin-obliged diabetics and 312 persons for control by means of the plaque-Index, the Oral-Hygiene-Index simplified. The DMF/T-Index and the Gingivitis-respectively Periodontal-Disease-Index for evaluation of the oral health situation. The comparison shows that the diabetic group has a moderate higher Plaque-pictures of gingivitis or periodontitis. This confirms our opinion that the diabetes mellitus is a risk-factor for the development of periodontal diseases. Therefore patients with diabetes mellitus should perform a very intensive care for mouth-hygiene.
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PMID:[Report on experiences with a one-year action at the Gondar College of Medical Sciences in Ethiopia. 3. Influence of diabetes mellitus on the teeth supporting apparatus]. 263 34

Inflammatory periodontal diseases are common in the United States. The incidence of gingivitis and periodontitis appears to be the same for persons with controlled diabetes as for those in the nondiabetic population. For patients with uncontrolled diabetes, however, periodontal diseases progress more rapidly than in their controlled counterparts. In addition, once a person with diabetes has periodontitis, the disease is usually more aggressive than in nondiabetic controls. These differences may be due to microangiopathy, altered polymorphonuclear leukocyte chemotaxis, increased dental plaque formation, or other causes. Patients with diabetes should be counseled to have a periodontal screening, which must include the use of a probe to measure the depth of the periodontal pockets. When problems are found, they should be treated and the patient should be placed in maintenance therapy.
Diabetes Educ
PMID:Periodontal diseases and diabetes. 267 37


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