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Query: UMLS:C0011849 (diabetes)
 277,896 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Three cases of pulmonary actinomycosis are reported. Case 1 was a 33-year-old man complaining of hemosputum. A large mass lesion was noted in the right upper lobe and surgically resected. Actinomycosis was diagnosed pathologically. The second case was a 41-year-old man with lung abscess. An actinomyces species was cultured by percutaneous aspiration biopsy. He was effectively treated with clindamycin. The third case was a 46-year-old man with a chronic cough and cavitary lesion. Gram staining of sputum revealed sulfur granules. Piperacillin was administered with prompt response. All three cases had dental disease and two had diabetes mellitus. In patients with a mass lesion or those with lung abscess not effectively treated by cephem antibiotics, actinomycosis should be suspected especially when diabetes mellitus and/or dental disease coexists. Adequate treatment may not always require long-term antibiotics.
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PMID:[Three cases of pulmonary actinomycosis]. 146 91

Actinomycosis is an uncommon bacterial infection that has a characteristic chronic indolent course. Patients with this infection frequently undergo multiple surgical procedures before a correct diagnosis is made. Perianal actinomycosis should be suspected if a nontender perianal mass is found to contain thin purulent material and small yellow particles (sulfur granules). The diagnosis is confirmed by special stains and anaerobic cultures. Recognition of this infection is important because successful treatment requires combined surgical and antibiotic therapy. We report two patients, one with diabetes mellitus and one with human immunodeficiency virus III, who had recurrent perianal abscesses caused by Actinomyces and were treated successfully with surgical drainage and antimicrobial therapy.
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PMID:Actinomyces as a cause of recurrent perianal fistula in the immunocompromised patient. 159 81

A 53-year-old woman was admitted with diabetes mellitus. After admission, a tumor shadow was detected by chest radiography and blood was found in her sputum. Despite further investigations, no definite diagnosis was made. Pulmonary wedge resection was performed because malignancy could not be excluded. Histological examination of the resected lung specimen led to the diagnosis of pulmonary actinomycosis. In Japan, 59 cases of pulmonary actinomycosis were reported between 1964 and 1993. These reports indicate that many cases of this disease are diagnosed by histological examination of resected lung specimens. Pulmonary actinomycosis has become even rarer recently because of the development of chemotherapy. We report this case and discuss the relevant literature.
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PMID:[Pulmonary actinomycosis presenting as a mass shadow with a cavity on chest radiography]. 773 Nov 23

Primary laryngeal actinomycosis is rare. The case of a woman with diabetes that presented with a 2-month history of hoarseness and cough is reported. The literature is reviewed and the clinical features and histology of laryngeal actinomycosis are discussed.
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PMID:[Primary laryngeal actinomycosis]. 923 41

A patient presented with a pelvic tumor which mimicked an advanced ovarian carcinoma with invasion into urinary bladder, rectum and uterus, as detected by MR imaging. After surgery, however, actinomycosis of the left ovary was diagnosed by pathological examination. Ovarian actinomycosis in this patient was complicated by diabetes mellitus.
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PMID:Ovarian actinomycosis complicated by diabetes mellitus simulating an advanced ovarian carcinoma. 1057 24

We report two cases of isolated abdominal wall actinomycosis and review 18 previously reported cases to further characterize the clinical findings and the therapeutic management of this syndrome. This diagnosis would be advocated in patients with a palpable abdominal mass of subacute appearance with a previous history of digestive medical illness, diabetes, abdominal surgery, or prolonged IUD use. In contrast with other actinomycosis locations, remarkable data were a more elevated mean age of patients; a female predominance; a prevalent location of mass in abdominal lower left quadrant; and a shorter duration of symptomatology before to diagnosis. The CT is the first choice for imaging study and percutaneous needle aspiration would be recommended for definite diagnosis. The long-term antibiotic therapy, with or without percutaneous drainage, is the first treatment choice because is very effective and made unnecessary a more invasive surgical management. The prognosis is excellent with adequated treatment.
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PMID:[Primary actinomycosis of the abdominal wall. Description of 2 cases and review of the literature]. 1132 3

Epidural abscess of the spinal column is a rare condition that can be fatal if left untreated. Risk factors for epidural abscess include immunocompromised states such as diabetes mellitus, alcoholism, cancer, and acquired immunodeficiency syndrome, as well as spinal procedures including epidural anesthesia and spinal surgery. The signs and symptoms of epidural abscess are nonspecific and can range from low back pain to sepsis. The treatment of choice in most patients is surgical decompression followed by four to six weeks of antibiotic therapy. Nonsurgical treatment may be appropriate in selected patients. The most common causative organism in spinal epidural abscess is Staphylococcus aureus. Spinal epidural abscess involving actinomycosis is rare.
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PMID:Spinal epidural abscess: a diagnostic challenge. 1199 16

The Population Council recently reworded the package labeling for the copper T380A IUD as follows: pelvic inflammatory disease (PID) is related to a woman's sexual behavior and not to the device itself. Formerly contraindicated, histories of PID or ectopic pregnancy are now merely precautions. The labeling now warns that the Copper T is contraindicated in the presence of PID or in women with a history of PID since the last pregnancy. If a woman has been free of infection, there is no need not to give her an IUD. The former contraindication about ectopic pregnancy has been deleted, while contraindications in the section of the label on conditions associated with increased susceptibility to infections with microorganisms now include only leukemia and AIDS. IV drug use and conditions requiring chronic corticosteroid therapy have been dropped from the section, along with diabetes. Finally, the former contraindication of genital actinomycosis has been changed to address symptomatic genital actinomycosis with organism confirmed by culture. This latter change is due to the high number of false-positives seen with Pap smears alone. These changes are logical given recent research findings about IUDs. A brief overview is given of recent findings about IUDs with regard to pelvic inflammatory disease, ectopic pregnancy, and diabetes.
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PMID:New label broadens IUD candidacy profile. History of some diseases now just a precaution. 1231 42

Contraceptive practice guidelines have the potential to assist health care providers in evaluating the needs and expectations of women seeking contraception, educating patients, and monitoring successful contraceptive use. This article presents guidelines for IUD patient selection developed by several members of the editorial board of the US newsletter, "Dialogues in Contraception." Misinformation about the IUD has prevented many clinicians and patients from considering this method, despite recent improvements in its design. The currently available data suggest that the two IUDs available in the US, Copper T 380A and Progestasert, cause a local reaction that is toxic to sperm (and perhaps ova), thereby preventing fertilization. Modern IUDs, which use only monofilament tails, do not increase the risk of pelvic inflammatory disease in women without evidence of lower genital tract infection. Beyond avoiding women at risk for sexually transmitted diseases, there are few barriers to IUD use. The method is appropriate for women who are contemplating but ambivalent about sterilization, aged under 25 years, perimenopausal, nulliparous or parous, postpartum or postabortion, lactating, and cigarette smokers over 35 years of age. Contraindications to IUD use are postpregnancy infection, unresolved acute cervicitis or vaginitis, distorted uterine cavity, uterine or cervical cancer, unexplained abnormal vaginal bleeding, increased susceptibility to infection, genital actinomycosis, immunocompromised patients, and diabetes mellitus (progesterone-releasing IUD only).
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PMID:IUD patient selection and practice guidelines. 1232 91

Actinomycosis is a granulomatous suppurative bacterial disease caused by anaerobic actinomyces, which presents primarily with the cervico-facial, thoracic, abdominal or pelvic form. Cutaneous involvement is well documented and it is usually secondary to local extension or exceptionally to ematogenous spreading from visceral sites. Primary cutaneous actinomycosis is very rare and usually associated with external trauma and/or local ischemia. We report on the case of a primary cutaneous actinomycosis of the forehead in a 59-year-old man with diabetes mellitus who had had a preceding cranial trauma and several cutaneous reconstructive surgical procedures. The patient was treated successfully with combined antibiotic therapy.
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PMID:Primary cutaneous actinomycosis of the forehead. 1270 79


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