Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
172,036 document(s) hit in 31,850,051 MEDLINE articles (0.07 seconds) .

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Human Gene/Protein
Sep 10427
Mol 2553
CA1 1979
brain-derived neurotrophic factor 1735
GABA 1617
insulin 1409
Gen 1216
cytokine 1179
NMDA receptor 1095
ATP 935
MRI 888
5-hydroxytryptamine 845
serotonin transporter 784
olfactory 761
gut 754
beta-endorphin 752
IL-6 735
lipopolysaccharide 682
ICD 680
CA3 665
tumor necrosis factor 647
CO2 635
She 632
TNF 630
Pol 602
prolactin 561
interferon 538
reserved 530
5-HT1A 526
metabotropic glutamate receptor 519
hemoglobin 511
glucocorticoid receptor 486
SCL 486
5-HTTLPR 464
ATPase 456
opioid receptor 456
Men 455
APA 440
ACTH 435
ANOVA 433
REM 432
C-reactive protein 425
glutamate receptor 419
CD4 410
superoxide dismutase 393
interleukin-6 389
growth hormone 372
corticotropin-releasing factor 369
albumin 367
AMP 354
ADHD 352
San 352
nitric oxide synthase 351
axonal 348
calcium channel 345
substance P 344
HPA 344
vasopressin 338
cage 336
catalase 332
oxytocin 331
MDD 320
CSF 311
acetylcholinesterase 306
short form 302
IFN 296
CBT 282
5-HT2A 277
IL-10 276
ionotropic 264
lymphoid 261
thymus 253
CGI 251
GSH 251
neurotrophic factor 250
amyloid precursor protein 244
tyrosine hydroxylase 244
LPS 244
leptin 241
thyroid hormone 240
calmodulin 238
CB1 237
GDS 236
neurotrophin 233
phosphodiesterase 233
MAO-A 232
CRH 228
Mot 222
collagen 221
renin 219
somatostatin 219
GAD 215
cytochrome P450 214
microsomal 214
anonymous 209
CREB 206
endoplasmic reticulum 206
ADP 205
ACS 204
serotonin receptor 199
mTOR 199
neuropeptide Y 198
creatine kinase 195
GABA(A) receptor 193
NR2B 192
NMR 184
alkaline phosphatase 181
Brain-derived neurotrophic factor 181
glucagon 181
adenylate cyclase 179
caspase-3 178
ERK1 177
adrenocorticotropic hormone 177
ASA 176
PHA 176
ERK 176
glial fibrillary acidic protein 176
MAC 173
B12 173
HDL 168
MAPK 168
inducible nitric oxide synthase 167
IL-1 167
glutathione peroxidase 167
Mem 166
TNF-alpha 165
Met 165
PSD-95 163
dopamine transporter 163
phosphatase 162
IL-2 161
angiotensin II 160
serum albumin 160
histone 158
TRH 158
RDC 154
cannabinoid receptor 153
IgA 152
cytochrome P-450 151
tryptophan hydroxylase 149
nodal 149
muscarinic receptor 148
adenylyl cyclase 147
Mal 147
p38 146
nerve growth factor 143
MAO-B 143
CD8 143
parvalbumin 142
calcitonin 141
c-fos 141
orexin 139
Mil 139
mGluR5 138
lactate dehydrogenase 138
thyrotropin-releasing hormone 138
calcineurin 137
interleukin-2 137
galanin 137
Aplysia 137
more...
Disease
depression 172036
major depressive disorder 11171
schizophrenia 5441
cancer 5009
mental illness 4679
suicide 4492
posttraumatic stress disorder 4321
anxiety disorders 4276
dementia 4256
psychosis 3715
diabetes 3586
Alzheimer's disease 3460
cognitive impairment 3289
stroke 3192
Parkinson's disease 3187
bipolar disorder 2864
hypertension 2633
HIV 2541
obesity 2352
epilepsy 2332
chronic pain 2254
ischemia 2069
mania 2043
psychological distress 1997
aggression 1861
violence 1856
AIDS 1856
affective disorder 1831
coronary artery disease 1726
myocardial infarction 1701
addiction 1608
substance abuse 1593
migraine 1580
obsessive-compulsive disorder 1529
substance use 1481
alcoholism 1454
myocardial ischemia 1438
suicide attempts 1424
cardiovascular disease 1406
anhedonia 1337
tumor 1309
autism 1265
postpartum depression 1262
neuroticism 1249
clinical depression 1223
multiple sclerosis 1172
sleep disturbances 1138
heart failure 1115
emotional distress 1102
panic disorder 1069
breast cancer 1014
CES 950
sleep disorders 946
confusion 923
delusions 903
hallucinations 830
rumination 830
asthma 826
ADHD 800
fibromyalgia 792
alcohol abuse 782
dysthymia 761
coronary heart disease 735
sexual abuse 727
cold 702
chronic disease 686
type 2 diabetes 684
chronic obstructive pulmonary disease 684
ICD 681
unipolar depression 678
heart disease 669
major depressive episode 659
anemia 643
HAM 637
delirium 636
drug abuse 622
acute myocardial infarction 619
sexual dysfunction 618
psychological stress 614
rheumatoid arthritis 605
eating disorder 604
malnutrition 594
arthritis 566
fits 564
sepsis 559
social phobia 553
osteoporosis 550
dysphoria 549
anorexia nervosa 536
parkinsonism 521
bipolar depression 516
sepsis 515
personality disorder 498
memory impairment 497
drug addiction 495
pruritus 494
borderline personality disorder 492
binge eating 488
irritable bowel syndrome 476
GAD 464
Syndrome 460
substance use disorders 446
panic attacks 440
West 435
Huntington's disease 431
coma 429
psychiatric diagnosis 428
metabolic syndrome 426
LTD 423
atherosclerosis 423
melancholia 416
immunodeficiency 408
SAD 407
hypothyroidism 400
Brown 400
hypomania 398
disinhibition 396
bulimia nervosa 392
renal disease 379
congestive heart failure 379
hypochondriasis 367
incontinence 366
systemic lupus erythematosus 365
sleep apnea 364
ECT 357
SEM 354
Abuse 349
HPA 344
chronic fatigue syndrome 344
infectious diseases 344
osteoarthritis 343
agoraphobia 335
abortion 332
conduct disorder 330
erectile dysfunction 325
psoriasis 325
obstructive sleep apnea 325
Depressive disorders 324
child abuse 323
xerostomia 322
emotionality 320
carcinoma 315
social stress 312
Autism 311
cerebral ischemia 309
hepatitis C 304
tetanus 303
infertility 299
encephalopathy 298
hyperglycemia 296
phobia 288
renal failure 288
adjustment disorder 280
hypoglycemia 279
paranoia 279
psychopathy 277
cardiomyopathy 276
Disorder 271
dehydration 267
chronic renal failure 265
more...
Symptom
pain 9782
fatigue 4534
anesthesia 2924
seizures 2525
insomnia 2436
headache 2124
angina 2079
analgesia 1651
Depressive symptoms 1424
sleepiness 1296
nausea 1264
stigma 1220
agitation 1130
anorexia 1125
hopelessness 1118
discomfort 995
vomiting 958
apathy 943
chest pain 879
diarrhea 768
weakness 710
dyspnea 692
tremor 668
discomfort 628
dizziness 616
constipation 586
despair 577
overweight 558
hypothermia 486
ataxia 453
alexithymia 443
exhaustion 417
acute stress 404
low back pain 380
nausea and vomiting 377
lethargy 352
hypercapnia 350
abdominal pain 340
back pain 333
tinnitus 327
cough 322
dystonia 285
memory loss 250
collapse 243
functional recovery 241
spasm 210
spasticity 206
hypersomnia 195
distraction 189
vertigo 187
myalgia 180
acute pain 173
cancer pain 167
arthralgia 166
bradykinesia 166
respiratory distress 163
starvation 160
hunger 155
Ill 150
asthenia 149
exertional angina 140
cachexia 131
hot flushes 129
syncope 117
menopausal symptoms 111
shortness of breath 108
hyperoxia 107
hot flashes 105
numbness 105
thinning 104
myoclonus 103
decreased appetite 103
Sedation 102
catatonia 102
Psychiatric symptoms 99
paresthesia 98
snoring 95
dysarthria 88
personality change 88
pelvic pain 87
facial pain 86
chronic back pain 84
tachypnea 81
forgetfulness 81
polyuria 76
paresis 76
colic 76
bloating 75
chorea 73
erythema 73
neck pain 72
hypotonia 71
incoordination 71
Neuropathic pain 69
flushing 64
twitching 64
motor symptom 64
Poor sleep 63
polydipsia 63
enuresis 62
physical appearance 61
splenomegaly 61
blurred vision 56
mental fatigue 53
muscle rigidity 53
cerebellar ataxia 53
hemiplegia 52
physical symptom 51
tense 51
cyanosis 51
nasal discharge 49
emaciation 48
anosmia 48
chills 47
hypocapnia 46
bewilderment 46
tingling 45
torticollis 45
lassitude 45
Postoperative pain 44
eds 44
tonic-clonic seizure 43
acidity 42
pallor 42
night sweats 41
bone pain 41
neuralgia 40
orofacial pain 40
photophobia 39
shoulder pain 39
hepatomegaly 39
regurgitation 38
asynergy 38
atypical chest pain 33
feeling depressed 33
heartburn 33
body pain 33
ENT 32
lightheadedness 32
Anoxia 32
elevated mood 31
wheezing 29
exertional dyspnea 29
blepharospasm 29
clonus 28
leg pain 27
excessive sweating 27
dysuria 27
knee pain 26
hypertonia 25
Extrapyramidal symptoms 25
stomach pain 24
limb pain 24
dry eye 24
abnormal gait 24
auditory hallucination 24
muscle stiffness 24
Excitability 24
Involuntary Movement 23
hyperacusis 23
more...
Drug
Spectrum 1289
Cardiovasc 748
Dermatol 456
Portal 442
caffeine 422
nitroglycerin 383
CSF 333
Check 279
Monit 202
Nephron 184
Ethanol 170
IL-2 162
lysine 161
Fentanyl 140
Asthma 135
Frontal 135
MAP 128
vitamin E 121
Escitalopram 119
Propofol 118
Leaf 118
ROC 112
Domperidone 111
Clonidine 104
NADH 104
Duloxetine 95
ascorbate 95
Mirtazapine 91
Spectrum 89
Atropine 86
ENT 85
IFN-gamma 84
Dial 84
lactose 78
Alliance 76
Agomelatine 75
PCP 74
CTX 73
EE2 73
TMS 72
DMI 62
CaCl2 62
ICI 61
Moclobemide 61
Prozac 60
Indomethacin 58
Histamine 56
CaCl2 55
CaCl2 55
Ringer's solution 53
CAM 52
niacin 51
Reboxetine 51
DBS 51
EPA 50
Diurnal 50
ROS 50
Retinoic acid 49
Reserpine 49
9-THC 48
Tianeptine 47
Bupivacaine 45
DEX 44
OIF 42
Isotretinoin 42
Phenytoin 40
p75 40
Modafinil 39
CFS 38
Bifidobacterium 38
DHT 35
DHT 35
Gabapentin 34
Ouabain 34
MDS 34
Nephron 32
Mutagen 32
Adriamycin 31
citric acid 31
Growth hormone 30
Growth hormone 30
Pramipexole 29
TAT 29
ABC 28
Angiotensin II 27
Apomorphine 27
BH4 27
Anafranil 27
Forskolin 26
Hyperforin 26
Sulpiride 26
Monensin 26
Scopolamine 26
Rimonabant 26
CDP 26
Vitamin B12 25
Fraction 25
Horizon 25
MRC 25
Pramipexole 25
PTH 25
Vitamin A 25
EPI 24
ADM 24
ALA 24
Theophylline 24
Atenolol 24
HCH 24
Ginseng 24
Norplant 24
Glucagon 23
Glutathione 23
Triad 23
MgSO4 23
Kenyan 23
DFP 23
Phentolamine 23
Vitamin E 22
pyridoxal phosphate 22
Triad 22
Estrogens 21
Gel 21
THF 20
Award 20
Anafranil 20
ACT 20
NVP 19
APD 19
Hypaque 19
NH3 19
Thiopentone 18
Zoloft 18
ampicillin 18
Pregabalin 18
Narcan 18
Butorphanol 17
Tubocurarine 17
FAD 17
Hypaque 17
IL-1ra 17
Norplant 17
Asn 16
DPA 16
Cimetidine 16
Ludiomil 15
Cimetidine 15
Captopril 15
G-CSF 15
IFN-beta 15
HCG 15
Ranitidine 15
Doxapram 15
CTX 14
Ritalin 14
Vitamin B 14
Parkin 14
CPR 14
Donepezil 14
Flunitrazepam 14
Ludiomil 14
more...
Enzyme
monoamine oxidase 917
protein kinase 775
mitogen-activated protein kinase 577
acetylcholinesterase 552
ATPase 496
superoxide dismutase 459
ERK 456
protein kinase C 446
catalase 379
cholinesterase 329
creatine kinase 272
tyrosine hydroxylase 237
phosphodiesterase 233
calcineurin 225
renin 219
ACS 206
alanine aminotransferase 204
adenylate cyclase 198
aspartate aminotransferase 193
alkaline phosphatase 181
focal adhesion kinase 173
NO synthase 171
glutathione peroxidase 168
lactate dehydrogenase 164
tryptophan hydroxylase 149
caspase-3 147
phospholipase C 141
peroxidase 139
ACE 130
CaMKII 125
GSK 118
AOR 115
indoleamine 2,3-dioxygenase 111
NOS 104
AMPK 99
guanylate cyclase 85
cytochrome oxidase 81
phospholipase A2 80
xanthine oxidase 78
CFI 76
luciferase 75
lysozyme 75
PCP 74
thrombin 74
proteasome 74
glutathione reductase 74
P-glycoprotein 71
reverse transcriptase 71
gamma-glutamyl transpeptidase 70
demethylase 66
CPT 65
glutathione S-transferase 65
AMP-activated protein kinase 65
trypsin 65
CAD 65
CAD 64
CAD 64
MAP 62
MEK 61
DAT 60
BIS 60
AST 59
CPT 58
CPT 57
succinate dehydrogenase 57
complex I 54
lipase 53
lipoprotein lipase 53
adenosine deaminase 48
adenosine deaminase 48
acid phosphatase 47
choline acetyltransferase 47
caspase-1 47
CYP3A4 47
MCS 45
alcohol dehydrogenase 44
PKG 44
ceruloplasmin 43
tissue plasminogen activator 43
glucose-6-phosphate dehydrogenase 43
monoacylglycerol lipase 42
thromboplastin 40
heme oxygenase 40
NADPH oxidase 38
NADPH oxidase 37
lipoxygenase 37
neuraminidase 36
CPR 36
diaphorase 36
glutamine synthetase 35
pyruvate dehydrogenase 34
plasmin 34
carbonic anhydrase 34
collagenase 33
pyruvate kinase 32
ornithine decarboxylase 31
APC 31
aldehyde dehydrogenase 31
phosphatidylinositol 3-kinase 30
TMT 29
TAT 29
aryl hydrocarbon hydroxylase 28
RNA polymerase 27
pyruvate dehydrogenase 27
pyruvate dehydrogenase 27
alpha-glucosidase 27
PDE 26
phosphoinositide 3-kinase 26
invertase 26
thyroid peroxidase 26
RNase 26
hexokinase 26
urokinase-type plasminogen activator 26
phosphorylase 25
beta-glucuronidase 25
chymotrypsin 24
AMPK 24
phosphofructokinase 24
GAS 24
alpha-amylase 24
citrate synthase 23
SPT 23
glyceraldehyde-3-phosphate dehydrogenase 23
arginase 23
RNase 23
lactase 22
glutamate dehydrogenase 22
DNA polymerase 22
ATP synthase 22
glutamate dehydrogenase 22
SPT 22
prostaglandin synthetase 22
CD10 22
acetyl-CoA carboxylase 21
glutamate dehydrogenase 21
PST 21
pepsin 21
HSD 21
glyceraldehyde-3-phosphate dehydrogenase 21
protein phosphatase 2A 21
BMT 21
aldehyde dehydrogenase 21
N-acetyltransferase 20
malate dehydrogenase 20
dopamine beta-hydroxylase 20
myosin ATPase 20
prolyl endopeptidase 19
glucose-6-phosphatase 19
aldehyde dehydrogenase 19
aldehyde dehydrogenase 19
botulinum neurotoxin 19
aldehyde dehydrogenase 19
elastase 18
GABA transaminase 18
5'-nucleotidase 18
5alpha-reductase 18
5alpha-reductase 18
NQO1 18
glyceraldehyde-3-phosphate dehydrogenase 18
MDP 18
more...
Compound
Clin 12553
Dec 11648
calcium 4214
DSM 4182
oxygen 3059
water 3007
glutamate 2860
5-HT 2717
glucose 2269
Cardiol 2057
sodium 2011
DNA 1655
GABA 1654
GABA 1630
ethanol 1612
noradrenaline 1369
potassium 1183
NMDA 1073
CO2 1055
CES 950
ATP 936
tryptophan 901
AMPA 884
tryptophan 882
nitric oxide 882
tryptophan 856
tryptophan 856
acetate 638
TNF 630
phosphate 604
gamma-aminobutyric acid 595
cAMP 543
arginine 528
iron 485
zinc 484
sulfate 481
nitrogen 465
ACTH 451
methionine 450
tyrosine 440
His 435
caffeine 426
LTD 424
AMP 375
salt 351
hydrogen 350
creatinine 344
Ketamine 343
Cereb 338
Malondialdehyde 337
urea 330
Mg2+ 305
TSH 295
Phe 278
Morphine 275
leucine 272
vitamin D 270
GSH 265
GSH 265
hydroxyindoleacetic acid 259
copper 257
Dopamine 256
Lithium 253
cGMP 252
Naloxone 251
serine 246
carbonate 244
nitrate 244
ADP 236
Cortisol 229
ASA 228
EPSP 226
lysine 221
alanine 214
glutamine 213
galactose 210
ADP 208
ADP 205
ACS 205
ACS 204
L-DOPA 200
Neuronal 195
ammonia 194
Imipramine 190
N2O 190
Imipramine 189
Glutamate 188
ACh 187
Adenosine 187
TRH 183
HCl 180
Diazepam 180
Nicotine 180
Dexamethasone 180
threonine 178
phosphorus 176
glycerol 169
5-hydroxytryptophan 167
Venlafaxine 167
iodine 167
Insulin 163
cysteine 159
acetic acid 159
Sertraline 154
Paroxetine 152
ammonium 148
Melatonin 148
Norepinephrine 147
Gly 146
cadmium 145
Hearts 144
PEG 144
Thyroid 143
propionic acid 142
propionic acid 142
Adrenal 141
SDS 140
silver 139
homocysteine 139
Estrogen 138
aspartic acid 138
bromide 137
Bupropion 136
DHA 135
6-12 134
aldosterone 133
Halothane 131
DBA 131
manganese 131
Pac 130
5-HIAA 130
Propofol 130
NH2 128
Cocaine 128
Asp 122
Citalopram 119
Propranolol 119
Optimal 119
methanol 118
DBA 117
DBA 117
Propranolol 115
Verapamil 114
NAD 114
Estrogen 113
Amitriptyline 112
pyridine 111
Verapamil 110
PEG 107
selenium 106
prostacyclin 105
NADH 104
nicotinamide 103
Nifedipine 102
cyanide 102
isoxazole 100
proline 99
H2O2 98
dicarboxylic acid 98
cobalt 97
more...