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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The objectives of this study were to determine the ability of the 30-, 15- and 8-item versions of the GDS for screening and assessing change in severity of depression in nursing home patients. The GDS and the MADRS were administered to 350 elderly NH-patients by trained interviewers. The presence of major (MaD) or minor depression (MinD) was evaluated with the Schedules for Clinical Assessment in Neuropsychiatry. Receiver Operator Characteristic (ROC) curves of the GDS-versions were performed to measure the ability to screen on depression. The ability to measure change in severity of depression was measured by differences in mean GDS-scores and mean MADRS-scores between patients with MaD, MinD and no depression, and expressed in terms of effect sizes. It was found that in ROC-curves all three GDS-versions performed well. The MADRS showed larger effect sizes for the differences between MaD, MinD and no depression than the GDS-versions. The effect sizes of the three GDS versions were comparable. We conclude that all three versions of the GDS can be used for screening on depression among NH-patients. The MADRS is superior to the GDS for assessment of (changes in) severity of depression, but the GDS also appears to be an acceptable instrument for this purpose and is less time-consuming.
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PMID:Screening for depression and assessing change in severity of depression. Is the Geriatric Depression Scale (30-, 15- and 8-item versions) useful for both purposes in nursing home patients? 1838 5

Correctly identifying asthma patients who need treatment for depression is part of comprehensive care. The objective of this study was to compare the prevalence of depressive symptoms measured by the short-form Center for Epidemiologic Studies Depression Scale (CESD-SF), which measures somatic and psychological symptoms, with the original and short-form Geriatric Depression Scale (GDS and GDS-SF), which measure only psychological symptoms. In total, 257 asthma patients (mean age 42 years, 75% women) completed the GDS (score range 0-30, positive screen > or = 11) and the CESD-SF (score range 0-30, positive screen > or = 10). The performance of each scale was compared to clinical diagnoses of depressive disorders reported by physicians using a skill score analysis. Twenty percent of patients had GDS scores > or = 11 and 32% had CESD-SF scores > or = 10. The somatic symptom of restless sleep was the most common CESD-SF symptom and the symptom that contributed most to the total score. The GDS had a skill score of +.16 (+1 = maximum possible, 0 = best guess) and the CESD-SF had a skill score of -.02 compared to physician-reported depressive disorders. Similar results were found for the GDS-SF. Thus, more patients had a positive CESD-SF screen, which was attributable mostly to a somatic sleep symptom that overlaps with asthma symptoms, and the GDS was more consistent with physicians' reports of depressive disorders.
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PMID:Psychological and somatic symptoms in screening for depression in asthma patients. 1841 30

Although several epidemiologic studies have assessed the relationship between low blood pressure and depressive symptoms in geriatric populations, the results have been inconsistent. Because the white-coat phenomenon is observed frequently in patients with depressive symptoms, we have considered that blood pressure measured in nonmedical settings is important in assessing the relationship between blood pressure and depressive symptoms among the geriatric population. The aim of this study was to investigate the relationships between home blood pressure and depressive symptoms in a community-based elderly population aged 70 years and over. We analyzed a cross-sectional survey comprised of 888 community-dwelling Japanese aged 70 years and older. Blood pressure was self-measured at home, and depressive symptoms were evaluated using the 30-item Geriatric Depression Scale (GDS 30) with a cutoff point of 11. The prevalence of depressive symptoms was 34.8%. For all subjects, after adjustments for potentially confounding factors, the odds ratios of having depressive symptoms by increasing quartiles of systolic blood pressure of subjects not taking antihypertensive drugs to subjects taking them were 1.00, 0.97, 0.88, 0.59, and 0.70. Statistically significant inverse relationships were observed in subjects not taking antihypertensive drugs. No apparent association between diastolic blood pressure and depressive symptoms was observed in any subjects or in a stratified analysis of antihypertensive drug use. In this study, a higher home systolic blood pressure was independently and continuously related to a lower prevalence of depressive symptoms in participants not using antihypertensive medication. Further study is required to clarify the causality of this relationship.
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PMID:Home blood pressure is associated with depressive symptoms in an elderly population aged 70 years and over: a population-based, cross-sectional analysis. 1849 59

The purposes of this study were: (i) to compare the extent of depression in the nursing home and community-dwelling elderly people, and (ii) to find the variables including residential status and other related variables explaining depression in Korea. Two sets of secondary data were combined and used to achieve the objectives of this study. One data set relating to elderly people in nursing homes was from a part of 2002 Kyunggi Long-term Care System Construction Study by Kyunggi Research Institute, Kyunggi province, Korea. The other data set for community-dwelling elderly people was from a part of 2001 National Long-term Care Study by Korea Institute for Health and Social Affairs. The data set for this study included 307 elderly people living in nursing homes and 166 elderly people living in the community. Depression was measured and determined using the geriatric depression scale-short form (GDS-SF) Korean version, with scores of 8 or higher to indicate possible depression. A total of 39.3%[95% confidence interval (CI); 32.1-46.9%] of the sample in the community elderly showed symptoms of depression, higher than the rate found in the nursing home elderly (24.0%) (95% CI; 19.5-29.2%). The mean (standard deviation) GDS-SF score for the elderly in the nursing home was 6.1 (3.4), and 7.4 (4.3) for elderly in the community, the difference being statistically significant [t (275.5) = -3.33; P < 001]. As a result of multiple logistic regression analysis, residential status has appeared as an important predictor after controlling other related variables. The adjusted odds ratio of depression associated with the nursing home residents in residential status, all other factors being equal, was 3.14 (95% CI; 1.30-7.58). Community-dwelling elderly people have higher odds of depression. These findings suggest that there is a need to provide adequate health-related care services for the elderly people in the community.
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PMID:Residential status and depression among Korean elderly people: a comparison between residents of nursing home and those based in the community. 1861 13

Elders with cognitive impairments frequently experience concomitant unidentified depressive symptoms due to an impaired capacity for verbal communication. Therefore, determination of a valid and reliable instrument with which to detect depression in this population requires confirmation through observation. The Cornell Scale for Depression in Dementia (CSDD) has been employed worldwide. However, no formally established psychometric properties have yet been made available for its Chinese version. For this study, we attempted to translate and test the validity and reliability of the CSDD Chinese version (CSDD-C). After completing translation and expert validity, a convenient sample of 145 older adults with dementia was assessed by their caregivers in several care facilities in Southern Taiwan. The CSDD-C was administered to collect data along with the Geriatric Depression Scale short form (GDS-SF). Results found an expert content validity index (CVI) of .92 and concurrent validity between CSDD-C and GDS-SF of .322 (p < .001). The number of factors extracted through our samples is consistent with the original CSDD; inter-rater agreement over a two-week period on each item was significant (Kappa = .43-.89); and the Cronbach's alpha for internal consistency reliability was .84. Results indicate the CSDD-C to be a reliable and valid instrument to help Chinese speaking caregivers determine signs and symptoms of depression in elders with dementia under their care.
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PMID:Psychometric evaluation of the Chinese version of the Cornell Scale for Depression in Dementia. 1879 90

We compared the quality of life (QOL) of older adults in a post-communist country (the Czech Republic) with those living in traditional western democracies. The sample comprised 1981 respondents aged 60+ (from 60 to 99). The subjective QOL was measured using the WHOQOL-BREF and the add-on module for older adults, the WHOQOL-OLD. The findings showed higher score of depressive symptoms measured by the GDS scale and lower QOL in Czech sample as compared to other centres. Analyses of factors related to QOL of older adults showed similar patterns for the Czech sample and other centres with depression emerging as the strongest determinant of reduced QOL Findings also underline that subjective quality of life measurement reflects cross-country differences in accordance with objective indicators of national prosperity.
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PMID:Demographic and psychosocial correlates of quality of life in the elderly from a cross-cultural perspective. 1911 40

Acculturative stress and relevant demographic variables, including immigration status, English skills, level of education, age, gender, country of origin, and years since immigration to the U. S. are examined along with their relationship to depressive symptoms. The 200 Arab-American and recent Arab immigrant participants ranged from age 60-92 and represented eight countries of origin. Most had limited fluency in English. Arabic versions of the Multi-dimensional Acculturative Stress Inventory (MASI) and Geriatric Depression Scale were administered. MASI and GDS results indicated greater degrees of acculturative stress and depression for those with a refugee or temporary resident status. More recent entry into the U.S. also predicted greater stress, while greater levels of education and English skills predicted lower levels of stress and depression. Composite stress levels and the nature of stress varied by country of origin. Although demographic variables were predictive of depression when examined separately, multiple regression analyses revealed that perceived acculturative stress, particularly pressure to learn English, provided a notable increment in prediction of depression over the demographic variables.
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PMID:Acculturative stress and depression in an elderly Arabic sample. 1926 7

The study explored whether apathy and depressive mood symptoms (DMS) are related to cognitive and functional features of dementia in 63 nursing home (NH) residents with early-onset dementia (EOD). All EOD residents from one NH (n = 41) and a random sample from another NH were assessed for depressive symptoms (Montgomery Asberg Depression Rating Scale [MADRS]), apathy (Neuropsychiatric Inventory [NPI]), global cognitive functions (Mini-Mental State Examination [MMSE]), activities of daily living (ADL, Minimum Data Set-Resident Assessment Instrument [MDS-RAI]), and overall dementia severity (Global Deterioration Scale [GDS]). DMS were not associated with apathy and dementia severity. Regression analyses adjusted for age, gender, the type of dementia, and DMS revealed that dementia severity measures accounted, respectively, for 14% (ADL), 13% (GDS), and 9% (MMSE) of the variance in apathy. In line with previous research in older patients, the higher apathy scores were associated with more cognitive and functional problems in EOD.
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PMID:Apathy and depressive mood in nursing home patients with early-onset dementia. 1934 2

The aim of the present study was to assess the presence of depressive symptomatology among elderly residents in long stay institution (LSI) and in the community of Recife, Brazil. In total, 81 LSI elderly patients (mean age of 75.55 + or - 9.18 years) and 132 elderly (mean age of 73.14 + or - 8.27 years) individuals from the community were evaluated. Depressive symptomatology was assessed by the geriatric depression scale (GDS-15), cognitive status by the mini mental state examination (MMSE) and capacity to perform the activities of daily living (ADL) by the Katz Index. Comorbidities and the use of medication were recorded. The LSI elderly exhibited more depressive symptoms (p < 0.001) and more dependency (p < 0.001). We observed no differences in MMSE (p = 0.058). The elderly in the community displayed more comorbidities and the LSI elderly consumed more medication (p < 0.001 and < 0.001, respectively). According to multivariate analysis (logistic regression), being male, having no spouse and having a low schooling level are risk factors for depressive symptoms. In conclusion, most elderly with depressive symptoms received no medication for depression.
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PMID:Undertreatment of depressive symptomatology in the elderly living in long stay institutions (LSIs) and in the community in Brazil. 1935 53

Little is known about the course of depressive symptoms in Parkinson's disease (PD). We studied the course of clinically significant depressive symptoms using data from two clinical trials that followed 413 early, untreated PD subjects for 12 to 18 months. We measured depressive symptoms with the 15-item geriatric depression scale (GDS-15); a score of > or =5 indicates clinically significant depressive symptoms. We used a time-dependent Cox model to examine the association between demographic variables, PD severity, and medication use on the time to resolution of depressive symptoms. One hundred fourteen of 413 (27.6%) subjects were screened positive for depression during the study, with a median GDS-15 score of 6, indicating mild symptoms. Within 6 months, 47% of subjects experienced remission of clinically significant depressive symptoms. Subjects with mild depressive symptoms were more likely to develop moderate to severe depressive symptoms (GDS > or = 10) than those without prior symptoms (relative risk = 6.16). Increasing severity of depressive symptoms, older age, and longer PD duration predicted a lower likelihood of symptom resolution (hazard ratios 0.83-0.92). Mild depressive symptoms have a variable course, with remission and development of more sustained and severe symptoms occurring over time. More severe depressive symptoms may herald a protracted course.
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PMID:The course of depressive symptoms in early Parkinson's disease. 1941 39


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