Gene/Protein
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Symptom
Drug
Enzyme
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Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
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Target Concepts:
Gene/Protein
Disease
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Query: UMLS:C0011570 (
depression
)
172,036
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Studies were carried out to determine the comparative toxicity and pathophysiology of 13 of the more poisonous snakes indigenous to Saudi Arabia. Included were four snakes from the Viperidae family, six from the Elapidae family, and three representative sea snakes from the family Hydrophidae. Anesthetized adult beagle dogs and anesthetized monkeys were used in the study. Vital physiological functions were continuously recorded as were changes in the blood coagulation system and any tissue damage produced by the venom at the site of envenomation. For the intravenous administration of the venom, lyophilized venom was obtained by "milking" each of the live specimens used in the study. Actual envenomation was accomplished by grasping the poisonous reptile and allowing the snake to strike the shaved exposed gluteal muscle of the anesthetized animal. Venom from the snakes of the family Viperidae produced death in an average of 3 hours. The average lethal dose was 1.13 mg/kg.
Depression
of first and second stage clotting factors was observed with these venoms as well as a decrease in fibrinogen levels and in platelet counts. Findings suggestive of intravascular coagulation were also observed with moderate hemolysis of the formed elements. Some local hemorrhage was seen at the site of envenomation. Venom from the Elapidae family of snakes produced death at an average of 1.7 hours. The average lethal dose was 0.70 mg/kg. Death appeared to be primarily due to respiratory paralysis following blockade at the neuromuscular junction. Only moderate hemolysis was seen with these venoms. No intravascular coagulation or tissue damage was seen. The venom of the family Hydrophidae consistently produced death in less than 30 minutes.(ABSTRACT TRUNCATED AT 250 WORDS)
Mil
Med 1992 Apr
PMID:1991 Sir Henry Wellcome Medal and Prize recipient. Medical studies of the poisonous land and sea snakes found in and around Saudi Arabia. 847 21
The purpose of this pilot study was to describe the 3-year experience of ambulatory medical care provided by one family physician in an Army community hospital. Data collected at each outpatient visit included the patient's age, race, gender, problems actively addressed, and procedures. There were 7,895 outpatient visits, representing 3,665 patients and 2,292 families. Of the 13,158 problems recorded, the 10 most frequent were pregnancy care, general medical examination, alcohol and tobacco use, hypertension,
depression
/anxiety, contraception, otitis media, acute upper respiratory infection, vaginitis, and headache. Further studies should be done to validate this pilot study.
Mil
Med 1992 Nov
PMID:The content of outpatient family practice care in an Army community hospital: one physician's three-year experience. 147 Mar 54
Psychiatric interviews were conducted with 55 male Army HIV+ patients. These soldiers were diagnosed in an early stage of HIV, and were not clinically demented. Sixty-four percent were given diagnoses of a depressive disorder by a psychiatrist, while 42% self-reported
depression
. Fifty-five percent had a history of suicidal thoughts since their diagnosis of HIV, but only one soldier was actively suicidal. Half said that they followed a more healthy lifestyle since their diagnoses. Factors associated with a high rate of
depression
included being divorced, of Hispanic origin, having other medical problems, or a history of mental illness. Not telling friends and family, or feeling a lack of support from them or the military, was also significantly correlated with
depression
.
Mil
Med 1992 Jul
PMID:Depression and support systems in male army HIV+ patients. 152 68
This study examined 100 randomly selected medical charts of Israeli psychiatric casualties of the 1982 Lebanon War in order to determine the clinical picture of combat stress reaction as recorded by clinicians on the battlefield. We found nine categories of symptoms. The most prevalent clinical picture (48% of cases) was polymorphic, followed by anxiety (13%) and labile states (11%). Only 41% of cases were mono-symptomatic and stable. Examination of the polymorphic and labile clinical pictures revealed that the most prominent symptomatology was anxiety and
depression
. In the labile states, the most widespread beginning symptom was anxiety and the most prevalent end state was found to be
depression
. These findings are discussed in light of reports from other wars.
Mil
Med 1991 Apr
PMID:The clinical picture of acute combat stress reaction among Israeli soldiers in the 1982 Lebanon War. 203 Aug 42
An analysis from the Finnish East and West Cohort of the Seven Countries Study tested the hypothesis that front line service during modern warfare is associated with
depression
later in life. World War Two-era Finnish combat veterans were compared to Finnish veterans who were non-combatants. Both groups were followed from 1959 to 1984. Dependent variables were the Zung
depression
scale and other measures of psychosocial adaptation and mental health. Analysis of variance of Zung scores by combat exposure was close to statistical significance (p = 0.0501). Even if statistical significance had been reached, it is felt that the absolute magnitude of the differences between the populations appear quite trivial. A significant association was found for those who had participated in over nine battles and when grouping
depression
, sleeplessness, paranoia, hallucinations, schizophrenia, and other mental illness into the general category of any mental illness (O.R. = 4.414; 95% C.I. = 1.113, 17.503). This seems to support the residual stress hypothesis pertaining to modern combat exposure.
Mil
Med 1991 May
PMID:Depression late after combat: a follow-up of Finnish World War Two veterans from the seven countries east-west cohort. 205 71
Dependent medical care at Army expense or at Army facilities during World War II was offered only on an emergency basis and at the discretion of the facility commanding officer. This had been the practice since 1884 when such care was specifically authorized by Congressional appropriation. Mobilization in 1898 and 1917 had brought a large number of state militiamen or inductees into the army--men who could leave their families behind. When mobilization began again in 1940, it was thought that a similar procedure would be followed. Events, however, overwhelmed the system as commanders of Army bases faced large numbers of young, pregnant wives who had followed their husbands. This had happened, in part, because of the dislocations of the Great
Depression
and, in part, because the wives of military inductees hoped to find work close to where their husbands were stationed. Although dependent medical care was not increased in proportion to the numbers of new dependents brought in by the war mobilization, medical care was provided for the four lower grades under the Emergency Maternity and Infant Care section of the Social Security Act of 1935. Subsequent to World War II and the experience of the Korean War, Congress saw it fit to specifically authorize medical care for dependents of military personnel as part of the soldiers' terms of employment, as a device to stimulate retention in service of both soldiers and doctors. In 1956 the United States Congress established the right at law of military dependents to medical care as specified in the Dependents' Medical Care Act.(ABSTRACT TRUNCATED AT 250 WORDS)
Mil
Med 1990 Feb
PMID:Military dependent medical care during World War II. 210 46
The prisoner of war (POW) experience is greatly influenced by the environmental and sociocultural factors of the particular captivity setting. Among the most important coping mechanisms are communication, maintenance of military social structure, and personality flexibility. Following repatriation some former POWs develop psychiatric disorders, most commonly 1) medico-psychiatric disorders due to illness, physical trauma, or nutritional deficit, 2) post-traumatic stress disorder, 3) adjustment disorder, 4)
depression
, 5) anxiety disorders, 6) substance use disorders, and 7) family problems. The severity of captivity and the presence or absence of social supports during and after the POW experience play major roles in the recovery or illness that may occur after repatriation.
Mil
Med 1990 Apr
PMID:The prisoner of war. 211 Mar 41
The present study examines the differences in the presentation of psychopathology between active duty military and veteran patients enrolled in alcohol rehabilitation programs. The Millon Clinical Multiaxial Inventory was used to assess personality disorders, clinical syndromes, and substance abuse. Most veterans were seen as having avoidant and dependent personality disorders as well as a great deal of anxiety and
depression
. Forty-seven percent were above cutoff scores for alcohol abuse. Air Force patients were predominantly narcissistic and antisocial with much less distress. Only 9% were classified psychometrically as abusers. The results indicate that not only are veteran alcoholics more chronic but that active-duty alcohol abusers are underreporting abuse and care must be used in their assessment.
Mil
Med 1990 Jul
PMID:Active-duty and veteran alcoholics: differences in psychopathology presentation. 212 74
Barbiturate anesthesia for cesarean section was well described by Kosaka almost 20 years ago. However, light balanced anesthesia has become the unofficial standard general anesthesia for cesarean section in this country. This light anesthetic technique could be catastrophic in the patient with raised intracranial pressure. The dilemma posed by cesarean section of a young woman with posterior fossa brain tumor led us to revive use of Kosaka's higher doses of thiobarbiturate. Together with regional and topical anesthesia of the larynx and trachea, this method resulted in stable maternal hemodynamics without resulting in neonatal
depression
.
Mil
Med 1989 Jun
PMID:Cesarean section in a patient with brain tumor: a clinical report. 249 72
Camptocormia, a sustained forward flexion of the trunk of functional origin, is relatively rare in peace time. It is usually attributed to the dynamics of conversion or psychophysiologic disorder. The association of camptocormia with
depression
of significant proportions has not been recorded elsewhere. A case report of such a problem in a Navy enlistee during peace time is presented. Treatment with antidepressants and supportive psychotherapy is advocated as a first step when
depression
occurs in patients with camptocormia.
Mil
Med 1989 Jul
PMID:Camptocormia and depression: a case report. 252 41
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