Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We assessed the diagnostic utility of the Symptom Checklist-90-Revised (SCL-90-R) in a sample of adolescent inpatients. In Part 1 (n = 79), convergent and discriminant validity were demonstrated for SCL-90-R scales measuring depression and paranoid ideation. Canonical correlation showed that SCL-90-R scales tapped two dimensions of adolescent psychopathology, a primary dimension of dysphoria and a secondary dimension of anger and mistrust. In Part 2 (n = 50), adolescents diagnosed as having major depression showed significant elevations on scales measuring depression, anxiety, and obsessive-compulsive features. Although several scales had high diagnostic specificity for major depression and conduct disorder, sensitivity was low.
 ...
PMID:Utility of the SCL-90-R with depressed and conduct-disordered adolescent inpatients. 148 8

In this study was compared the mental health status of 47 multiple sclerosis patients with silver/mercury tooth fillings (amalgams) to that of 50 patients with their fillings removed. On the Beck Depression Inventory the multiple sclerosis subjects with amalgams suffered significantly more depression while their scores on the State-Trait Anger Expression Inventory indicated the former group also exhibited significantly more anger. On the SCL-90 Revised, subjects with amalgam fillings had significantly more symptoms of depression, hostility, psychotism, and were more obsessive-compulsive than the patients with such fillings removed. On a questionnaire containing 18 mental health symptoms multiple sclerosis subjects with amalgam fillings reported a history of 43% more symptoms than those without amalgam fillings over the past 12 months. These data suggested that the poorer mental health status exhibited by multiple sclerosis subjects with dental amalgam fillings may be associated with mercury toxicity from the amalgam.
 ...
PMID:A comparison of mental health of multiple sclerosis patients with silver/mercury dental fillings and those with fillings removed. 149 84

In order to examine the relationship of self-rated inhibited anger to somatization, the authors administered several self-rating scales, including the SCL-90 and a Likert scale pertaining to inhibited anger, to psychiatric patients and family practice patients of both sexes. In a linear stepwise regression, depression predicted inhibited anger in all four groups. Previous studies have reported an association of inhibited anger and somatization; the present study suggests that depression is the link between the two in the majority of patients. The relationship of inhibited anger to depression may have implications for psychotherapy.
 ...
PMID:Self-rated inhibited anger, somatization and depression. 151 17

We directly compared scores on the self-rated Beck Depression Inventory with two other common rating scales that assess a wider range of psychopathology, including depression, the self-rated Symptom Check List-90--R (SCL-90--R), and the clinician-rated Brief Psychiatric Rating Scale for 71 inpatients who suffered from depression (n = 50) and other disorders. All measures of depression showed robust correlations among themselves. The self-rated scales correlated better between themselves than with the clinician-rated scale. Since the SCL-90--R assesses depression as well as the Beck inventories, is also a self-report instrument, yet provides a richer description of psychopathology with little extra effort, it may have some advantage over the latter.
 ...
PMID:Comparison of three depression rating scales. 152 63

The HRSD, HRSA, SCL-90 scales were psychometrically investigated in a cross-national sample of patients with varieties of non-psychotic symptoms of anxiety and depression. Across the cultural backgrounds the scores obtained from the original versions of these scales are not sufficient statistics. However, latent structure analysis has identified homogeneous subscales for depression (the HRSD) and for discomfort (an SCL subscale). High concurrent validity was found between the subscales of depression, anxiety and discomfort. In international research, inhomogeneity among scale items can be confounded with group differences which are usually ascribed to drug differences.
 ...
PMID:The Hamilton scales and the Hopkins Symptom Checklist (SCL-90). A cross-national validity study in patients with panic disorders. 152 Nov 18

The symptomatology of 15 borderline (BDL) depressed and 45 non-BDL depressed consecutive inpatients was assessed using the Hamilton depression scale (HAM-D) and the 90-item Symptoms Checklist (SCL-90) self-rating questionnaire. No significant differences were found in the total scorings of the two instruments in the two groups of patients. However, while non-BDL depressive rated significantly higher in items related to melancholic forms of depression, BDL depressives showed less specific symptoms, and the persistence, or possibly the magnification, of their maladaptive personologic structure. Two discriminant analyses, performed on the ratings at the HAM-D and SCL-90 of the two groups of patients, suggested that although the total degree of severity may be the same, the depressive episodes of BDL patients are qualitatively different from those of patients with less maladaptive personologic traits.
 ...
PMID:The nature of depression in borderline depressed patients. 154 97

This article presents the results of a comparison between the validity of the SCL anxiety, phobic anxiety and depression scales and the GHQ-28 anxiety-/insomnia and severe depression scales in a psychiatric outpatient population. Validity was studied at a categorical level with DSM-III diagnosis, and at a dimensional level with a prototypical anxiety and a prototypical depression scale. The SCL anxiety and depression scales and the GHQ depression scale all showed good convergent and divergent validity, however the GHQ anxiety/insomnia scale showed neither convergent nor divergent validity. It is concluded that as a screening instrument, the relative shortness of the GHQ-28 is a considerable advantage over the SCL-90. However, the GHQ-12 may be an even better alternative. As a multi dimensional measure of psychopathology, the SCL-90 is to be preferred, because it covers more dimensions. If one is interested in anxiety, the SCL-90 also seems the better choice.
 ...
PMID:Validity of the GHQ and SCL anxiety and depression scales: a comparative study. 157 83

The Zurich prospective epidemiological study included 591 twenty-year old subjects. At age twenty-eight, 457 of these people (228 males, 234 females) were re-examined and 415 of them at age thirty (197 males, 218 females). The DSM III-R definition of hypomania was modified. We found the following prevalences: 1.7% with hypomania, 3% with bipolar syndromes, 18.6% with major depression (including mood disorders) and 12.3% with short recurrent depression. Compared to male subjects, the risk of major depression was twice as high in female subjects but was roughly the same for the other groups. The study compares three groups of subjects: subjects with hypomania (UM), bipolar subjects (BP) and unipolar depression. Considerable differences were found depending on the levels of treatment, positive family histories for depression or hypomania and attempted suicides. The results show that the distinction between a subject with hypomania and a bipolar subjects is not clear. The ratings of the Hopkins Symptom Checklist scales (SCL 90-R), and of the FPI personality test (Fahrenberg et al., 1973) are presented and discussed. 12.7% of major depression cases were bipolar and 8.3% of short depressions were recurrent. In this sample of normal Swiss population, the ratio of bipolar to unipolar syndromes was approximately 1:5.
 ...
PMID:[Hypomania. Apropos of a cohort of young patients]. 160 Sep

Twenty women with bulimia nervosa (BN) and 20 women with obsessive-compulsive disorder (OCD) were compared on responses to the Minnesota Multiphasic Personality Inventory (MMPI), Symptom Checklist-90-Revised (SCL-90-R), and the Beck Depression Inventory (BDI). Multivariate analyses showed no significant differences between bulimic and OCD women on the MMPI, although a greater number of bulimic women showed significant elevations on several of the clinical scales. Analyses of SCL-90-R profiles indicated higher scores on somatization, interpersonal sensitivity, and psychoticism in the BN sample. Bulimic women did not differ significantly from OCD women on either obsessive-compulsive measures or other measures of anxiety. Similarities and differences in symptom profiles between these two groups are discussed, as well as their implications for alternative treatment approaches for BN.
 ...
PMID:Comparative psychopathology of women with bulimia nervosa and obsessive-compulsive disorder. 164 68

Psychological correlates of peptic ulcer were assessed in a group of volunteer patients whose ulcers were identified by endoscopy. Logistic regression analysis and "t" test indicates that the peptic ulcer patients studied had higher "neuroticism" scores on EPQ, more life events experienced in the year previous to the investigation (on the revised Holmes' Social Readjustment Rating Scale), more severe symptoms on SCL-90, and lower social support scores on the Social Support Rating Scale than matched controls. The most frequently reported SCL-90 symptoms were anxiety, depression, somatization and obsession. The relationship between the occurrence of peptic ulcer and the characteristics of personality, life events, social support and psychological health level is discussed.
 ...
PMID:[Psychologic correlates in peptic ulcer]. 175 80


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>