Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0011570 (
depression
)
172,036
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A study was made of migration activity (MA) of peritoneal macrophages of Syrian hamsters after
depression
of their antitumor natural resistance (NR) induced by injection by heat-inactivated tumor cells. The MA and
depression
of NR were most pronounced between day 14 and day 20 after inoculation of the animals with inactivated tumor cells of E-1 and
STHE
-LM8 tumor cells. Inoculation of the hamsters with heat-inactivated tumor cells of another strain (parenteral
STHE
) did not induce NR
depression
or enhanced MA of peritoneal macrophages of the treated animals. It is concluded that
depression
of antitumor NR essential for tumor induction and growth is apparently connected with alterations in the functional activity of macrophages, possibly with their suppressor activity.
...
PMID:[Migration activity of peritoneal exudate cells of Syrian hamsters at different times after suppression of their natural resistance to tumors]. 405 20
