Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We reported a 61-year-old woman who developed the associated movements in oculomotor muscles after the clipping of the IC-PC aneurysm which had produced the oculomotor palsy. It has generally been assumed that the phenomenon is the result of an aberrant regeneration of oculomotor nerve fibers. The sign of the aberrant regeneration may include any of the following: Pseudovon Graefe sign: retraction and elevation of the lid on downward gaze. Gaze lid dyskinesis: elevation of the involved lid on adduction of the eye. Inability to elevate or depress the globe: the globe neither elevates nor depress in up or down gaze. Retraction of the globe: the globe can be seen to retract on vertical movement. Adduction of the involved eye on attempted depression or elevation. Pseudo-Argyll Robertson pupil: the dilated pupil will not react to light but will contract when the medial rectus, inferior rectus, or elevators of the eye are stimulated. Monocular optokinetic response: in testing the vertical optokinetic response, the normal eye responds as usual but the affected eye either remains stationary or will show a slight horizontal nystagmus. All but category 4 were noted in our case.
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PMID:[Case of cerebral aneurysm producing the aberrant regeneration of the oculomotor nerve]. 649 21

We describe three patients with aberrant regeneration of the third nerve secondary to traumatic brain injury. The full blown features of the syndrome include horizontal gaze-eyelid synkinesis, pseudo-Graefe sign, limitation of elevation and depression of the eye with retraction of the globe on attempted vertical movements, adduction of the involved eye on attempted elevation or depression, pseudo-Argyll Robertson pupil and absent vertical optokinetic response. The 'misdirection' incidence in our study is 15%.
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PMID:Aberrant regeneration of the third nerve. 1119 20