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Query: UMLS:C0011570 (depression)
 172,036 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Recent prospective studies suggest that thyroid state plays a role in affective disorders. A lack of thyroid hormones can lower the threshold for depression; an excess can contribute to a state of tense dysphoria. Thyroid function in some persons also appears to influence the course of affective disorders. Adequate mobilization of thyroid hormones favors recovery from depression; excess mobilization increases the risk of mania in vulnerable individuals. Although other mechanisms may be involved, evidence suggests that the modulation by thyroid hormones of the beta-adrenergic receptor response to catecholamines may contribute to these effects. Norepinephrine stimulates such receptors; thyroid hormones increase their ability to receive stimulation. The plausibility of such interactions between catecholamines and thyroid hormones occurring in the CNS is strengthened by their common origin in the amino acid tyrosine and by their synergism in many metabolic processes.
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PMID:A hypothesis of thyroid-catecholamine-receptor interaction. Its relevance to affective illness. 625 96

Two epidemiological surveys of suicidal ideation were conducted among adolescents, aged 15-18, in France and the Canadian province of Quebec. The results suggest that, in both countries, suicidal ideation was linked to drug use (especially tobacco, illicit drugs, and psychotropic medicine), nonspecific somatic complaints (especially tiredness, sleep difficulties, depression, and feeling tense), a lack of self-esteem (pessimism, instability, boredom), and dissatisfaction with family relationships. There was no relationship between suicidal ideation and sports activities in either country. The implications for prevention are discussed.
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PMID:Suicidal thoughts among adolescents: an intercultural approach. 823 50

Fifty-eight outpatients with panic disorder (PD) were examined to determine their clinical features in comparison with a cohort of 52 patients with generalised anxiety disorder (GAD). Both groups were of comparable age, sex, educational level, marital status and ethnicity. PD patients were more likely to complain of palpitations, breathlessness, chest pain, numbness, choking sensations and especially fear of dying. GAD patients tended to complain of feeling tense, insomnia, headaches, weakness, restlessness and muscle aches. PD patients had greater comorbidity especially with agoraphobia and depression. Contrary to other reports, there were more males than females in both groups but alcohol dependence and suicide attempts were relatively rare. PD symptoms seemed more distressing, caused more social and occupational disruption, led to more requests for medical investigations and earlier psychiatric consultations. These factors seemed to suggest that panic disorder is a more severe illness than generalised anxiety disorder.
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PMID:Panic disorder in Singapore: clinical features and comparisons with generalised anxiety disorder. 920 72

Preliminary study of the psychologic adjustment of watermen with exposure to Pfiesteria piscicida was conducted on watermen with the most severe exposures and their occupationally matched controls. Participants in the exposed group were seven symptomatic recreational and commercial fishermen who had direct exposure to the Pocomoke River or other estuarial waters on Maryland's Eastern Shore before, during, and/or after periods of documented fish kills and Pfiesteria activity. The control group included eight commercial fishermen who worked on the ocean side of the Eastern Shore and had no reported exposure to estuaries with documented Pfiesteria activity. Both exposed symptomatic and nonexposed watermen completed the Profile of Mood States to assess depression, anxiety, and other relevant mood states as part of their participation in the larger investigation of the human health effects of Pfiesteria piscicida. Preliminary results suggest that both exposed symptomatic and nonexposed watermen are psychologically healthy and exhibit what psychologists refer to as the classic Iceberg Mood Profile. The Iceberg Profile is characterized by endorsement of symptoms suggestive of high energy, enthusiasm and positive mood (e.g., lively, active, energetic, cheerful, vigorous, etc.) and relative minimization of symptoms suggestive of negative or depressed mood (e.g., tense, anxious, restless, grouchy, forgetful). Therefore, the Pfiesteria-related symptom complex documented in the exposed watermen cannot be explained by functional or psychiatric factors and is probably due to exposure.
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PMID:Psychologic adjustment of watermen with exposure of Pfiesteria piscicida. 960 Nov 99

The association between mental health disorders beginning in adolescence and disorders in early adulthood is increasingly acknowledged. The mental health of adolescents has not been studied in the eastern area of Taiwan, where the mortality of teenagers is highest in Taiwan. The purpose of this study was to assess psychiatric symptoms among senior high school students in Hualien City, and to identify their associated factors. A total of 1,195 students were selected, via a stratified cluster sampling method, from nine high schools in Hualien City. A self-administered questionnaire was used to assess students' demographic characteristics, neurotic traits, perceived daily-life stress, social support, and psychiatric symptoms. There were 1,141 valid responses. From principal components analysis, depression-anxiety, impulsivity-paranoia, and psychoticism-obsession were found to be the most common self-rated psychiatric symptoms. About 70% of the students felt blue, 48.2% reported urges to injure someone, and 25% felt tense. Overall, about 5% to 10% of high school students had severe psychiatric symptoms. Stress from schoolwork, peer relationships, and neurotic traits were important predictors of psychiatric symptoms. The findings of this study imply that screening for psychiatric symptoms at senior high schools is essential for improving the mental health of students. The mental health care of adolescents should be school-based and in collaboration with medical professionals. Life skills must be taught at school.
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PMID:Self-rated psychiatric symptoms and their correlates among senior high school students in Hualien City. 979 26

Depression is common in patients with stroke and other neurological conditions. Accurate assessment and diagnosis is critical in understanding the causes of mood disturbance in these patients and in establishing effective treatments. Examination of mood states, however, is difficult in patients with aphasia, impaired emotional expression, and other communication and cognitive difficulties. Most standardized measures of mood are inappropriate for this population due to the instruments' linguistic, attention, and other cognitive demands. The Visual Analog Mood Scales (VAMS) are psychometrically sound measures, developed specifically for neurologically impaired patients in general and aphasic patients in particular. These very brief scales assess eight mood states: sad, happy, tense, afraid, tired, energetic, confused, and angry. The utility of these scales in clinical practice is presented, as are specific recommendations and guidelines for the assessment of mood in patients with aphasia and other communication deficits.
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PMID:Assessment of mood states in aphasia. 1010 Mar 75

In today's healthcare environment, characterized by downsizing, restructuring, mergers, and acquisitions, organizational cultures and employees are experiencing rapid--and often tense--changes. Ritual can facilitate change by acknowledging it and allowing the grieving process to take its course. The success of an organizational culture change can depend on whether the organization and its members have been given an opportunity to grieve. Until they grieve their losses, people cannot embrace the new. Organizational leaders who have survived downsizing must come to grips with their own survivor status first and then lead others in the organization through the current painful but irrevocable shift in their relationship to the organization. The use of ritual helps organizational survivors see the connection between the grieving process and their survivor symptoms of denial, anger, depression, guilt, fear, insecurity, anxiety, and uncertainty. A good ritual should allow those present to rise above barriers that separate, worries that overburden, and blindness that limits and to gather as one with God. As a rule, a good ritual is participative and recognizes the audience's diversity. The ritual should not just address those present but invite them to act, pray, or sing. Ritual is an important way to provide a structure that allows people to express their emotions. For leaders, it can be a visible way to acknowledge grief and show support for organizational members. For ritual to have any meaning, key leaders need to be present and perhaps have a role in the creation and enactment of the ritual.
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PMID:Ritual's role in profound change. 1014 60

Mood disorders are common in patients with neurodegenerative disease. Accurate diagnosis and assessment of mood changes are a crucial requirement for establishing reliable correlations with functional neuroanatomical changes, investigating their causes, and establishing effective treatment strategies. However, differential diagnosis of mood disorders is difficult in elderly patients with aphasia, impaired emotional expression, and other cognitive and neurobehavioral impairments. Although specific assessment of internal mood state would improve diagnostic accuracy, most standardized measures of mood are not appropriate for this population. The Visual Analog Mood Scales (VAMS) are valid, standardized measures, developed specifically for neurologically impaired patients, which assess eight moods: sad, happy, tense, afraid, tired, energetic, confused, and angry. The utility of these very brief scales is presented, as are specific recommendations and guidelines for the diagnosis of depression and other mood disorders in patients with neurodegenerative disease, such as dementia, Parkinson's disease, and stroke.
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PMID:Assessment of Mood States in Neurodegenerative Disease: Methodological Issues and Diagnostic Recommendations. 1032 Apr 34

The paper describes symptoms of mixed depressive and anxiety disorder (ICD-10). The study was carried out in three medical dispensaries: two psychiatric (42 persons) and one primary care (62 persons). Patients with or without anxiety and depressive symptoms were included. Exclusion criteria was: psychoactive substance abuse, physical diseases affecting mental state, and mental disorders other than anxiety or mood disorders. A total of 104 patients (65 women and 39 men in mean age of 41.1 years) were inquired with General Health Questionnaire (GHQ-30), Global Assessment of Functioning (GAF) and diagnostic questionnaire based on Schedules for Clinical Assessment in Neuropsychiatry, Version 2.0. There was no pattern of symptoms specific for mixed disorder that could be a basis for operational criteria. The most frequent were symptoms of generalised anxiety disorder (GAD), depression and dysthymia. The most specific symptoms, selected using discriminant analysis were: (1) difficulty in concentrating, (2) feeling mentally tense, (3) feeling of hopelessness or despair, (4) shortening of breath, (5) lowered mood, (6) feeling dizzy, unsteady, faint, or light headed; (7) early waking up, (8) nightmares, (9) dry mouth, (10) hot flushes or cold chills, (11) frequent tearfulness. The results contribute to the concept that mixed depression and anxiety disorder is closely related to generalised anxiety disorder (GAD).
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PMID:[Symptoms profile of mixed anxiety and depressive disorder]. 1184 6

The present study investigated the relationships between mental health (measured by the General Health Questionnaire--6 factors: General Illness, Somatic Symptoms, Sleep Disturbance, Social Dysfunction, Anxiety and Dysphoria, Suicidal Depression), coping styles (two strategies: Cognitive centered, Emotional centered), and mood (Tense Arousal, Energetic Arousal). 96 students answered questionnaires before their semester test which was a stressor. Analysis showed that (1) Tense Arousal scores correlated positively with overall General Health scores and all General Health factor scores, and Energetic Arousal scores correlated negatively with overall General Health scores and all General Health factor scores except one; (2) Anxiety and Dysphoria scores predicted Tense Arousal scores the best of General Health factor scores, while both Social Dysfunction scores and General Illness scores predicted Energetic Arousal scores. (3) Participants with high Energetic Arousal scores used a Cognitive centered coping strategy much more than an Emotional centered coping strategy. That is, people with low Energetic Arousal scores seem to use the Emotional centered coping strategy and have anxiety/dysphoria, while people with high Energetic Arousal scores seem to use a Cognitive centered coping strategy and have good health and social activity. These results suggest that there are small but significant relationships among mental health, coping styles, and mood.
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PMID:Relationships among mental health, coping styles, and mood. 1206 3


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